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Research ArticleNeurointervention

Guglielmi Detachable Coils versus Matrix Coils: A Comparison of the Immediate Posttreatment Results of the Embolization of 364 Cerebral Aneurysms in 307 Patients: A Single-Center, Single-Surgeon Experience

V. Katsaridis, C. Papagiannaki and C. Violaris
American Journal of Neuroradiology October 2006, 27 (9) 1841-1848;
V. Katsaridis
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C. Papagiannaki
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C. Violaris
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Article Figures & Data

Tables

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    Table 1:

    Patient characteristics

    GDCsMatrix CoilsTotal
    Patients (%)187 (60.9)120 (39.1)307
    Age, mean (range)52.4 ± 13.9 (21–80)52 ± 12 (20–79)52.8 (20–80)
    Sex, M/F96/9161/59157/150
    With ruptured aneurysm (%)160 (85.6)100 (83.3)260 (84.7)
        Hunt and Hess grades I–III121 (75.6)56 (56)177 (68.1)
        Hunt and Hess grades IV–V39 (24.4)44 (44)83 (31.9)
        ICH34 (21.25)20 (20)54 (20.8)
        ICH removal11 (6.9)13 (13)24 (9.2)
        Post-SAH hydrocephalus38 (23.8)23 (23)61 (23.5)
    With unruptured aneurysm (%)27 (14.4)20 (16.7)47 (15.3)
    With multiple aneurysms (%)28 (15)22 (18.3)50 (16.3)
        ×218 (9.6)13 (10.8)31 (10.1)
        ×38 (4.3)3 (2.5)11 (3.6)
        ×404 (3.3)4 (1.3)
        ×51 (0.5)2 (1.7)3 (1)
        ×61 (0.5)01 (0.3)
    • Note:—GDC indicates Gugliemi detachable coil; ICH, intracerebral hematoma; SAH, subarachoid hemorrhage.

    • View popup
    Table 2:

    Characteristics of aneurysms treated

    GDCsMatrix CoilsTotal
    Aneurysms harbored230159389
    Embolized aneurysms (%)219 (95.2)145 (91.2)364 (93.6)
    Nonembolized aneurysms (%)11 (4.8)14 (8.8)25 (6.4)
        Wide neck6 (54.6)4 (28.6)10 (40)
        Branch from sac4 (36.4)3 (21.4)7 (28)
        Severe condition1 (9.1)7 (50)8 (32)
    Ruptured160 (73.1)100 (69)260 (71.4)
    Unruptured59 (26.9)45 (31)104 (28.6)
    Anterior circulation (%)198 (90.4)134 (92.4)332 (91.2)
        ICA71 (32.4)54 (37.2)125 (34.3)
        AcomA65 (29.7)49 (33.8)114 (31.3)
        MCA47 (21.5)23 (15.9)70 (19.2)
        ACA15 (6.9)8 (5.5)23 (6.3)
    Posterior circulation (%)21 (9.6)11 (7.6)32 (8.8)
        BA14 (6.4)6 (4.1)20 (5.5)
        VA5 (2.3)4 (2.8)9 (2.5)
        PCA1 (0.5)01 (0.3)
        PICA1 (0.5)1 (0.7)1 (0.3)
    Aneurysm size, mean ± SD5.8 ± 1.35.3 ± 1.15.7 ± 1.0
    (range) (mm)(2–26)(2–25)(2–26)
    Neck size, mean ± SD2.3 ± 0.42.7 ± 0.52.6 ± 0.4
    (range) (mm)(1–5)(1–6)(1–6)
    • Note:—GDC indicates Gugliemi detachable coil; ICA, internal carotid artery; AcomA, anterior communicating artery; MCA, middle cerebral artery; ACA, anterior cerebral artery; BA, basilar artery; VA, vertebral artery; PCA, posterior cerebral artery; PICA, posterior inferior cerebral artery.

    • View popup
    Table 3:

    Angiographic results

    GDCsMatrix CoilsTotal
    Aneurysms coiled219145364
    Total occlusion, 95–100% (%)196 (89.5)128 (88.3)324 (89)
    Near-total occlusion 90–94% (%)14 (6.4)15 (10.3)29 (8)
    Incomplete occlusion < 90%(%)9 (4.1)2 (1.4)11 (3)
    Vasospasm detected (%)67/16061/100128/260
    (41.9)(61)49.2)
    Improvement with papervine (%)42/6741/6183/128
    (62.7)(67.2)(64.8)
    Angioplasty (%)13/1604/10017/260
    (8.1)(4)(6.5)
    Angioplasty successful (%)12/134/416/17
    (92.3)(100)(94.1)
    • Note:—GDC indicates Gugliemi detachable coil.

    • View popup
    Table 4:

    Procedural complications, clinical significance, and procedure-related mortality and morbidity

    GDCsMatrix CoilsTotal
    Complications38/194 (19.6)*19/123 (15.6)57/317 (18)
    Mortality7/187 (3.7)3/120 (2.5)10/307 (3.3)
    Morbidity5/187 (2.7)2/120 (1.7)7/307 (2.3)
    Aneurysm rupture13/194 (6.7)6/123 (4.9)19/317 (6)
        Mortality3/187 (1.6)1/120 (0.8)4/307 (1.3)
        Morbidity1/187 (0.5)1/120 (0.8)2/307 (0.7)
    Thromboembolic11/194 (5.7)7/123 (5.7)18/317 (5.7)
        Mortality2/187 (1.1)1/120 (0.8)3/307 (1)
        Morbidity2/187 (1.1)1/120 (0.8)3/307 (1)
    Parent artery occlusion3/194 (1.6)1/123 (0.8)4/317 (1.3)
        Mortality1/187 (0.5)01/307 (0.3)
        Morbidity1/187 (0.5)01/307 (0.3)
    Loop prolapse4/194 (2.1)3/123 (2.4)7/317 (2.2)
        Mortality01/120 (0.8)1/307 (0.3)
        Morbidity1/187 (0.5)01/307 (0.3)
    Coil breakage4/194 (2.1)04/317 (1.3)
        Mortality000
        Morbidity000
    Hemorhage following angioplasty1/194 (0.5)01/317 (0.3)
        Mortality1/187 (0.5)01/307 (0.3)
        Morbidity000
    ICA dissection2/194 (1)2/123 (1.6)4/317 (1.3)
        Mortality000
        Morbidity000
    • Note:—GDC indicates Gugliemi detachable coil; ICA, internal carotid artery.

    • * Values in parentheses are percentages.

    • View popup
    Table 5:

    Clinical outcome

    GDCMatrix CoilsTotal
    Total patients187120307
        mRS 0–2133 (71.1)*77 (64.2)210 (68.4)
        mRS-3–520 (10.7)18 (15)38 (12.4)
    Death34 (18.2)25 (20.8)59 (19.2)
    Unruptured aneurysm patients272047
        mRS 0–225 (92.6)19 (95)44 (93.6)
        mRS-3–52 (7.4)1 (5)3 (6.4)
        Death000
    Ruptured aneurysm patients160100260
        mRS 0–2108 (67.5)58 (58)166 (63.9)
        mRS-3 dN518 (11.3)17 (17)35 (13.5)
        Death34 (21.3)25 (25)59 (22.7)
    Hunt and Hess grades I–III12156177
        mRS 0–2100 (82.6)48 (85.7)148 (81.9)
        mRS 3–513 (10.7)4 (7.1)17 (9.6)
        Death8 (6.6)4 (7.1)12 (6.8)
    Hunt and Hess grades IV–V394483
        mRS 0–28 (20.5)10 (22.7)18 (21.7)
        mRS 3–55 (12.8)13 (29.6)18 (21.7)
        Death26 (66.7)21 (47.7)47 (66.6)
    • Note:—GDC indicated Gugliemi detachable coil; mRS, modified Rankin Scale.

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American Journal of Neuroradiology: 27 (9)
American Journal of Neuroradiology
Vol. 27, Issue 9
October 2006
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V. Katsaridis, C. Papagiannaki, C. Violaris
Guglielmi Detachable Coils versus Matrix Coils: A Comparison of the Immediate Posttreatment Results of the Embolization of 364 Cerebral Aneurysms in 307 Patients: A Single-Center, Single-Surgeon Experience
American Journal of Neuroradiology Oct 2006, 27 (9) 1841-1848;

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Guglielmi Detachable Coils versus Matrix Coils: A Comparison of the Immediate Posttreatment Results of the Embolization of 364 Cerebral Aneurysms in 307 Patients: A Single-Center, Single-Surgeon Experience
V. Katsaridis, C. Papagiannaki, C. Violaris
American Journal of Neuroradiology Oct 2006, 27 (9) 1841-1848;
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