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Improved Turnaround Times | Median time to first decision: 12 days

OtherBRAIN

Prominent Perivenular Spaces in Multiple Sclerosis as a Sign of Perivascular Inflammation in Primary Demyelination

Yulin Ge, Meng Law, Joseph Herbert and Robert I. Grossman
American Journal of Neuroradiology October 2005, 26 (9) 2316-2319;
Yulin Ge
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Meng Law
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Joseph Herbert
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Robert I. Grossman
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    Fig 1.

    “Prominent perivenular spaces” sign in a 43-year-old patient with multiple sclerosis. (A) Proton attenuation image (TR/TE, 7900/17) shows a widening perivenular space as stringlike hyperintensity (arrows) projecting radially from 2 small multiple sclerosis lesions following the course and configuration of deep venular structures. (B) FLAIR MR image (TR/TE/TI, 9010/92/2500) shows the increased intensity (arrows) (not cerebrospinal fluid intensity) within these prominent perivenular spaces. (C) Enhanced T1-weighted image (TR/TE, 600/27) shows an enhancing vein (arrow) in one lesion. (D) Proton attenuation image shows another lesion (arrow) with this prominent perivenular spaces sign.

  • Fig 2.
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    Fig 2.

    (A) “Prominent perivenular space” sign (arrow) follows the central course of the veins along which the lesions spread on T2-weighted image (TR/TE, 7900/119) in a 51-year-old patient. (B) Prominent perivenular spaces sign (arrow) without apparent association with lesions on T2-weighted image in a 33-year-old patient.

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    Fig 3.

    Schematic drawing illustrates the perivenular inflammatory infiltrates that cause lesion formation and enlarged perivenular spaces in multiple sclerosis. The prominent perivenular spaces can be with (bottom vessel) or without (top vessel) lesion association.

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American Journal of Neuroradiology: 26 (9)
American Journal of Neuroradiology
Vol. 26, Issue 9
1 Oct 2005
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Prominent Perivenular Spaces in Multiple Sclerosis as a Sign of Perivascular Inflammation in Primary Demyelination
Yulin Ge, Meng Law, Joseph Herbert, Robert I. Grossman
American Journal of Neuroradiology Oct 2005, 26 (9) 2316-2319;
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Cite this article
Yulin Ge, Meng Law, Joseph Herbert, Robert I. Grossman
Prominent Perivenular Spaces in Multiple Sclerosis as a Sign of Perivascular Inflammation in Primary Demyelination
American Journal of Neuroradiology Oct 2005, 26 (9) 2316-2319;

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