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Glioblastoma Multiforme of the Conus Medullaris in a Child: Description of a Case and Literature Review

Alessandro Stecco, Claudia Quirico, Amelia Giampietro, Giuseppe Sessa, Renzo Boldorini and Alessandro Carriero
American Journal of Neuroradiology September 2005, 26 (8) 2157-2160;
Alessandro Stecco
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Claudia Quirico
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Amelia Giampietro
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Giuseppe Sessa
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Renzo Boldorini
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Alessandro Carriero
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    Fig 1.

    A–C, Fast spin-echo T2-weighted sagittal acquisition (A) shows a hyperintense and homogeneous mass at the T12 level, involving the conus and the epicomus, with a diffuse aspect and without a clear cleavability plane. Spin-echo T1-weighted sagittal (B) and coronal (postgadolinium) (C) acquisitions show a hypointense lesion with a mild patchy nodular enhancement of the upper portion, associated with a faint enhancement along the pial surface.

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    Fig 2.

    A–C, Nine-month follow-up after surgery. Fast spin-echo T2-weighted (A) and spin-echo T1-weighted (postgadolinium) (B) sagittal lumbar spine acquisitions show a local recurrence of the disease. Note the leptomeningeal spread (B, C) along the entire spinal canal, up to the posterior cerebral fossa (C).

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    Fig 3.

    Photomicrograph of histologic findings shows glioblastoma multiforme. Note high cellular attenuation, pleomorphism, and mitosis of neoplastic cells (hematoxylin and eosin, original magnification ×400).

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    Fig 4.

    Photomicrograph of histologic findings shows anti-Ki67 (MIB-one) antiserum indicating a high-proliferating index in neoplastic cells (immunoperoxidase, hematoxylin counterstaining, original magnification ×400).

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American Journal of Neuroradiology: 26 (8)
American Journal of Neuroradiology
Vol. 26, Issue 8
1 Sep 2005
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Cite this article
Alessandro Stecco, Claudia Quirico, Amelia Giampietro, Giuseppe Sessa, Renzo Boldorini, Alessandro Carriero
Glioblastoma Multiforme of the Conus Medullaris in a Child: Description of a Case and Literature Review
American Journal of Neuroradiology Sep 2005, 26 (8) 2157-2160;

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Glioblastoma Multiforme of the Conus Medullaris in a Child: Description of a Case and Literature Review
Alessandro Stecco, Claudia Quirico, Amelia Giampietro, Giuseppe Sessa, Renzo Boldorini, Alessandro Carriero
American Journal of Neuroradiology Sep 2005, 26 (8) 2157-2160;
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