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Research ArticleNeurointervention

Prospective Analysis of Cerebral Infarction After Carotid Endarterectomy and Carotid Artery Stent Placement by Using Diffusion-Weighted Imaging

Hong Gee Roh, Hong Sik Byun, Jae Wook Ryoo, Dong Gyu Na, Won-Jin Moon, Byung Boong Lee and Dong-Ik Kim
American Journal of Neuroradiology February 2005, 26 (2) 376-384;
Hong Gee Roh
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Hong Sik Byun
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Jae Wook Ryoo
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Dong Gyu Na
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Won-Jin Moon
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Byung Boong Lee
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Dong-Ik Kim
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    Fig 1.

    Case of a 65-year-old man with symptomatic moderate stenosis (49%) of the left carotid bifurcation.

    A–C, Pre-CEA angiogram (A), pre-CEA DW image (B), and post-CEA DW image. Post-CEA DW image demonstrates a single, new, small hyperintensity (arrow) in the left striatocapsule near the small old lacune. This lesion was silent.

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    Fig 2.

    Case of a 68-year-old man with severe stenosis (91%) of the right ICA, who claimed severe unilateral headache after the third post-CEA day.

    A–D, Pre-CEA angiogram (A), post-CEA T2-weighted MR image (B), post-CEA DW image (C), and post-CEA gradient-echo MR image (D). Post-CEA MR images show severe vasogenic edema with focal hemorrhage (arrow) in the right cerebral hemisphere.

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    Fig 3.

    Case of a 58-year-old man with symptomatic moderate stenosis (69%) of the right ICA.

    A–D, Pre-CAS angiogram (A), pre-CAS DW image (B), post-CAS angiogram (C), post-CAS DW image (D). Post-CAS DW image demonstrates several small hyperintensities in the right cerebral hemisphere including the striatocapsule. Mild left-sided weakness and visual field defect occurred after CAS.

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    TABLE 1:

    Baseline characteristics of the treatment groups

    CharacteristicCEA Procedures (n = 26)CAS Procedures (n = 22)
    Age (y), mean (range)64.9 (48–77)61.5 (37–80)
    Sex, no (%)
        Male22 (92)*20 (100)*
        Female2 (8)0 (0)
    Presenting symptom, no. (%)
        Transient ischemic attack and/or amaurosis fugax5 (19)3 (14)
        Cerebral and/or retinal infarction14 (54)15 (68)
        Asymptomatic7 (27)4 (18)
    Pretreatment carotid artery
        Ipsilateral stenosis, no. (%)
            Mean percentage stenosis ± SD77.9 ± 13.276.3 ± 14.0
            Moderate (40–70%)7 (27)8 (36)
            Severe (>70%)19 (73)14 (64)
        Ipsilateral plaque ulceration, no. (%)21 (80)18 (82)
        Contralateral stenosis, no. (%)
            Mean percentage stenosis ± SD20.4 ± 30.559.2 ± 42.1
            None or <20% stenosis17 (62)6 (27)
            Mild (20–40%)4 (15)1 (4)
            Moderate (40–70%)3 (12)3 (14)
            Severe (>70%)2 (8)4 (18)
            Occlusion1 (4)8 (36)
    • * Two patients underwent bilateral CEA and two patients underwent bilateral CAS.

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    TABLE 2:

    Posttreatment results in the two groups

    Posttreatment ResultCEA (n = 26)CAS (n = 22)
    Unchanged DW image25 (96)14 (64)
    New hyperintensity on DW image1 (4)8 (36)
    Symptomatic hyperintensity on DW image0 of 1 (0)2 of 8 (25)
    Neurological and/or visual deficit1 (4)3 (14)
    Nonischemic complication5 (19)0 (0)
    Total symptomatic complications5 (19)3 (14)
    • Note.—Data are number (%) of procedures.

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    TABLE 3:

    Rate of new hyperintensity on DW image according to the angiographic variables

    Angiographic VariablesCEA (n = 26)CAS (n = 22)
    Ipsilateral ICA stenosis
        Severe0 (0 of 19)29 (4 of 14)
        Moderate1 (1 of 7)50 (4 of 8)
    Contralateral ICA stenosis
        Occlusion or severe33 (1 of 3)33 (4 of 12)
        Normal to moderate0 (0 of 23)40 (4 of 10)
        Ipsilateral ICA plaque ulcer
        Present5 (1 of 21)33 (6 of 18)
        Absent0 (0 of 5)50 (2 of 4)
    • Note.—Data are percentage (number) of procedures in which a new hyperintensity was noted for that angiograpic variable.

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American Journal of Neuroradiology: 26 (2)
American Journal of Neuroradiology
Vol. 26, Issue 2
1 Feb 2005
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Cite this article
Hong Gee Roh, Hong Sik Byun, Jae Wook Ryoo, Dong Gyu Na, Won-Jin Moon, Byung Boong Lee, Dong-Ik Kim
Prospective Analysis of Cerebral Infarction After Carotid Endarterectomy and Carotid Artery Stent Placement by Using Diffusion-Weighted Imaging
American Journal of Neuroradiology Feb 2005, 26 (2) 376-384;

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Prospective Analysis of Cerebral Infarction After Carotid Endarterectomy and Carotid Artery Stent Placement by Using Diffusion-Weighted Imaging
Hong Gee Roh, Hong Sik Byun, Jae Wook Ryoo, Dong Gyu Na, Won-Jin Moon, Byung Boong Lee, Dong-Ik Kim
American Journal of Neuroradiology Feb 2005, 26 (2) 376-384;
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Cited By...

  • Ischemic cerebral lesions after Carotid Stenting versus Carotid Endarterectomy: A Systematic review and Meta-Analysis
  • Safety and Efficacy of Remote Ischemic Preconditioning in Patients With Severe Carotid Artery Stenosis Before Carotid Artery Stenting: A Proof-of-Concept, Randomized Controlled Trial
  • New Ischemic Brain Lesions on Diffusion-Weighted MRI after Carotid Artery Stenting with Filter Protection: Frequency and Relationship with Plaque Morphology
  • Proximal Embolic Protection: A "Game Changer" for Carotid Stents
  • New Brain Lesions After Carotid Stenting Versus Carotid Endarterectomy: A Systematic Review of the Literature
  • Incidence of New Brain Lesions After Carotid Stenting With and Without Cerebral Protection
  • Silent Cerebral Ischemia Detected With Diffusion-Weighted Imaging in Patients Treated With Protected and Unprotected Carotid Artery Stenting
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