Research ArticleBrain
Giant Tumefactive Perivascular Spaces
Karen L. Salzman, Anne G. Osborn, Paul House, J. Randy Jinkins, Adam Ditchfield, James A. Cooper and Roy O. Weller
American Journal of Neuroradiology February 2005, 26 (2) 298-305;
Karen L. Salzman
Anne G. Osborn
Paul House
J. Randy Jinkins
Adam Ditchfield
James A. Cooper

References
- ↵
- ↵Song CJ, Kim JH, Kier EL, Bronen RA. MR imaging and histologic features of subinsular bright spots on T2–weighted MR images: Virchow-Robin spaces of the extreme capsule and insular cortex. Radiology 2000;214:671–677
- ↵Pollock H, Hutchings M, Weller RO, Zhang ET. Perivascular spaces in the basal ganglia of the human brain: their relationship to lacunes. J Anat 1997;191:337–346
- ↵Heier LA, Bauer CJ, Schwartz L, et al. Large Virchow-Robin spaces: MR –clinical correlation. AJNR Am J Neuroradiol 1989;10:929–936
- ↵
- ↵
- ↵Homeyer P, Cornu P, Lacomblez L, et al. A special form of cerebral lacunae: expanding lacunae. J Neurol Neurosurg Psychiatr 1996;61:200–202
- ↵Jungreis CA, Kanal E, Hirsch WL, et al. Normal perivascular spaces mimicking lacunar infarction: MR imaging. Radiology 1988;169:101–102
- ↵Ogawa R, Okudera T, Fukasawa H, et al. Unusual widening of Virchow-Robin spaces: MR appearance. AJNR Am J Neuroradiol 1995;16:1238–1242
- ↵Poirier J, Barbizet J, Gaston A, Meyrignac C. Thalamic dementia. Expansive lacunae of the thalamo-paramedian mesencephalic area. Hydrocephalus caused by stenosis of the aqueduct of Sylvius. Rev Neurol (Paris) 1983;139:349–358
- ↵Poirier J, Gray F, Gherardi R, Derouesné C. Cerebral lacunae. A new neuropathological classification. J Neuropathol Exp Neurol 1985;44:312
- ↵
- ↵Benhaìem-Sigaux N, Gray F, Gherardi R, et al. Expanding cerebellar lacunae due to dilatation of the perivascular space associated with Binswanger’s subcortical arteriosclerotic encephalopathy. Stroke 1987;18:1087–1092
- ↵Demaerel P, Wilms G, Baert AL. Widening of Virchow-Robin spaces [letter]. AJNR Am J Neuroradiol 1996;17:800–801
- ↵Vital C, Julian J. Widespread dilatation of perivascular spaces: A leukoencephalopathy causing dementia. Neuroradiology 1997;48:1310–1313
- ↵Fénelon G, Gray F, Wallays C, et al. Parkinsonism and dilatation of the perivascular spaces (état criblé) of the striatum: A clinical magnetic resonance imaging and pathological study. Movement Disorders 1995;10:754–760
- ↵Yetkin FZ, Fischer ME, Papke RA, Haughton VM. Focal hyperintensities in cerebral white matter on MR images of asymptomatic volunteers: correlation with social and medical histories. Am J Roentgenol 1993;161:855–858
- ↵Bokura H, Kobayashi S, Yamaguchi S. Distinguishing silent lacunar infarction from enlarged Virchow-Robin spaces: a magnetic resonance imaging and pathological study. J Neurol 1998;245:116–22
- ↵Mascalchi M, Salvi F, Gordano U, et al. Expanding lacunae causing triventricular hydrocephalus. Report of two cases. J Neurosurg 1999;91:669–674
- ↵Komiyama M, Yasui T, Izumi T. Magnet resonance imaging features of unusually dilated Virchow-Robin spaces—two case reports. Neurol Med Chir 1998;38:161–164
- ↵
- ↵Gerard G, Weisberg LA. MRI periventricular lesions in adults. Neurology 1986;36:998–1001
- ↵Drayer BP. Imaging of the aging brain. Part I. Normal findings Radiology 1988;166:785–796
- ↵Awad IA, Johnson PC, Spetzler RF, Hodak JA. Incidental subcortical lesions identified on magnetic resonance imaging in the elderly II. Postmortem pathological correlations. Stroke 1986;17:1090–1097
- Elster AD, Richardson DN. Focal high signal on MR scans of the midbrain caused by enlarged perivascular spaces: MR-pathologic correlation. AJR Am J Roentgenol 1991;156:157–160
- ↵Braffman BH, Zimmerman RA, Trojanowski JQ, Gonatas NK, Hickey WF, Schlaepfer WW. Brain MR: pathologic correlation with gross and histopathology. 1. Lacunar infarction and Virchow-Robin spaces. AJR Am J Roentgenol 1988;151:551–558
- ↵
- ↵Fazekas F, Kleinert R, Roob G, et al. Histopathologic analysis of foci of signal loss on gradient-echo T2*-weighted MR images in patients with spontaneous intracerebral hemorrhage: Evidence of microangiopathy-related microbleeds. AJNR Am J Neuroradiol 1999;20:637–642
- ↵Derouesné C, Gray F, Escourolle R, Castaigne P. ‘Expanding cerebral lacunae’ in a hypertensive patient with normal pressure hydrocephalus. Neuropath Appl Neurobiol 1987;13:309–320
- ↵Weller RO. Pathology of cerebrospinal fluid and interstitial fluid of the CNS: significance for Alzheimer disease, prion disorders and multiple sclerosis. J Neuropathol Exp Neurol 1998;57:885–894
- ↵Weller RO, Massey A, Newman TA, Hutchings M, Kuo YM, Roher AE. Cerebral amyloid angiopathy: amyloid beta accumulates in putative interstitial fluid drainage pathways in Alzheimer’s disease. Am J Pathol 1998;153:725–733
- ↵Preston SD, Steart PV, Wilkinson A, Nicoll JAR, Weller RO. Capillary and arterial cerebral amyloid angiopathy in Alzheimer’s disease: defining the perivascular route for the elimination of amyloid beta from the human brain. Neuropathol Appl Neurobiol 2003;29:106–117
- ↵Roher AE, Kuo YM, Esh C, et al. Cortical and Leptomeningeal Cerebro-Vascular Amyloid and White Matter Pathology in Alzheimer’s Disease. Molecular Medicine 2003;9:112–122
- ↵Sato N, Sze G, Awad I, et al. Parenchymal perianeurysmal cystic changes in the brain: Report of five cases. Radiology 200;215:229–233
- ↵Osborn AG. Brain Digital Teaching File. Salt Lake City: Advanced Medical Imaging Reference Systems;2003
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Karen L. Salzman, Anne G. Osborn, Paul House, J. Randy Jinkins, Adam Ditchfield, James A. Cooper, Roy O. Weller
Giant Tumefactive Perivascular Spaces
American Journal of Neuroradiology Feb 2005, 26 (2) 298-305;
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