Skip to main content
Advertisement

Main menu

  • Home
  • Content
    • Current Issue
    • Accepted Manuscripts
    • Article Preview
    • Past Issue Archive
    • Video Articles
    • AJNR Case Collection
    • Case of the Week Archive
    • Case of the Month Archive
    • Classic Case Archive
  • Special Collections
    • Advancing NeuroMRI with High-Relaxivity Contrast Agents
    • AJNR Awards
    • Low-Field MRI
    • Alzheimer Disease
    • ASNR Foundation Special Collection
    • Photon-Counting CT
    • View All
  • Multimedia
    • AJNR Podcasts
    • AJNR SCANtastic
    • Trainee Corner
    • MRI Safety Corner
    • Imaging Protocols
  • For Authors
    • Submit a Manuscript
    • Submit a Video Article
    • Submit an eLetter to the Editor/Response
    • Manuscript Submission Guidelines
    • Statistical Tips
    • Fast Publishing of Accepted Manuscripts
    • Graphical Abstract Preparation
    • Imaging Protocol Submission
    • Author Policies
  • About Us
    • About AJNR
    • Editorial Board
    • Editorial Board Alumni
  • More
    • Become a Reviewer/Academy of Reviewers
    • Subscribers
    • Permissions
    • Alerts
    • Feedback
    • Advertisers
    • ASNR Home

User menu

  • Alerts
  • Log in

Search

  • Advanced search
American Journal of Neuroradiology
American Journal of Neuroradiology

American Journal of Neuroradiology

ASHNR American Society of Functional Neuroradiology ASHNR American Society of Pediatric Neuroradiology ASSR
  • Alerts
  • Log in

Advanced Search

  • Home
  • Content
    • Current Issue
    • Accepted Manuscripts
    • Article Preview
    • Past Issue Archive
    • Video Articles
    • AJNR Case Collection
    • Case of the Week Archive
    • Case of the Month Archive
    • Classic Case Archive
  • Special Collections
    • Advancing NeuroMRI with High-Relaxivity Contrast Agents
    • AJNR Awards
    • Low-Field MRI
    • Alzheimer Disease
    • ASNR Foundation Special Collection
    • Photon-Counting CT
    • View All
  • Multimedia
    • AJNR Podcasts
    • AJNR SCANtastic
    • Trainee Corner
    • MRI Safety Corner
    • Imaging Protocols
  • For Authors
    • Submit a Manuscript
    • Submit a Video Article
    • Submit an eLetter to the Editor/Response
    • Manuscript Submission Guidelines
    • Statistical Tips
    • Fast Publishing of Accepted Manuscripts
    • Graphical Abstract Preparation
    • Imaging Protocol Submission
    • Author Policies
  • About Us
    • About AJNR
    • Editorial Board
    • Editorial Board Alumni
  • More
    • Become a Reviewer/Academy of Reviewers
    • Subscribers
    • Permissions
    • Alerts
    • Feedback
    • Advertisers
    • ASNR Home
  • Follow AJNR on Twitter
  • Visit AJNR on Facebook
  • Follow AJNR on Instagram
  • Join AJNR on LinkedIn
  • RSS Feeds

AJNR Awards, New Junior Editors, and more. Read the latest AJNR updates


Improved Turnaround Times | Median time to first decision: 12 days

Research ArticleBrain

Giant Tumefactive Perivascular Spaces

Karen L. Salzman, Anne G. Osborn, Paul House, J. Randy Jinkins, Adam Ditchfield, James A. Cooper and Roy O. Weller
American Journal of Neuroradiology February 2005, 26 (2) 298-305;
Karen L. Salzman
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Anne G. Osborn
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Paul House
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
J. Randy Jinkins
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Adam Ditchfield
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
James A. Cooper
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Roy O. Weller
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
  • Article
  • Figures & Data
  • Info & Metrics
  • Responses
  • References
  • PDF
Loading

References

  1. ↵
    Ozturk MH, Aydingoz U. Comparison of MR signal intensities of cerebral perivascular (Virchow-Robin) and subarachnoid spaces. J Comput Assist Tomogr 2002;26:902–904
    CrossRefPubMed
  2. ↵
    Song CJ, Kim JH, Kier EL, Bronen RA. MR imaging and histologic features of subinsular bright spots on T2–weighted MR images: Virchow-Robin spaces of the extreme capsule and insular cortex. Radiology 2000;214:671–677
    PubMedWeb of Science
  3. ↵
    Pollock H, Hutchings M, Weller RO, Zhang ET. Perivascular spaces in the basal ganglia of the human brain: their relationship to lacunes. J Anat 1997;191:337–346
  4. ↵
    Heier LA, Bauer CJ, Schwartz L, et al. Large Virchow-Robin spaces: MR –clinical correlation. AJNR Am J Neuroradiol 1989;10:929–936
    Abstract/FREE Full Text
  5. ↵
    Shiratori K, Mrowka M, Toussaint A, Spalke G, Bien S. Extreme, unilateral widening of Virchow-Robin spaces: case report. Neuroradiology 2002;44:990–992
    CrossRefPubMed
  6. ↵
    Kanamalla US, Calabro F, Jinkins JR. Cavernous dilatation of mesencephalic Virchow-Robin spaces with obstructive hydrocephalus. Neuroradiology 2000;42:881–884
    CrossRefPubMed
  7. ↵
    Homeyer P, Cornu P, Lacomblez L, et al. A special form of cerebral lacunae: expanding lacunae. J Neurol Neurosurg Psychiatr 1996;61:200–202
    Abstract/FREE Full Text
  8. ↵
    Jungreis CA, Kanal E, Hirsch WL, et al. Normal perivascular spaces mimicking lacunar infarction: MR imaging. Radiology 1988;169:101–102
    PubMedWeb of Science
  9. ↵
    Ogawa R, Okudera T, Fukasawa H, et al. Unusual widening of Virchow-Robin spaces: MR appearance. AJNR Am J Neuroradiol 1995;16:1238–1242
    Abstract
  10. ↵
    Poirier J, Barbizet J, Gaston A, Meyrignac C. Thalamic dementia. Expansive lacunae of the thalamo-paramedian mesencephalic area. Hydrocephalus caused by stenosis of the aqueduct of Sylvius. Rev Neurol (Paris) 1983;139:349–358
    PubMed
  11. ↵
    Poirier J, Gray F, Gherardi R, Derouesné C. Cerebral lacunae. A new neuropathological classification. J Neuropathol Exp Neurol 1985;44:312
  12. ↵
    Ugawa Y, Shirouzu I, Terao Y, et al. Physiological analyses of a patient with extreme widening of Virchow-Robin spaces. J Neurol Sci 1998;159:25–27
    CrossRefPubMed
  13. ↵
    Benhaìem-Sigaux N, Gray F, Gherardi R, et al. Expanding cerebellar lacunae due to dilatation of the perivascular space associated with Binswanger’s subcortical arteriosclerotic encephalopathy. Stroke 1987;18:1087–1092
    Abstract/FREE Full Text
  14. ↵
    Demaerel P, Wilms G, Baert AL. Widening of Virchow-Robin spaces [letter]. AJNR Am J Neuroradiol 1996;17:800–801
    FREE Full Text
  15. ↵
    Vital C, Julian J. Widespread dilatation of perivascular spaces: A leukoencephalopathy causing dementia. Neuroradiology 1997;48:1310–1313
  16. ↵
    Fénelon G, Gray F, Wallays C, et al. Parkinsonism and dilatation of the perivascular spaces (état criblé) of the striatum: A clinical magnetic resonance imaging and pathological study. Movement Disorders 1995;10:754–760
  17. ↵
    Yetkin FZ, Fischer ME, Papke RA, Haughton VM. Focal hyperintensities in cerebral white matter on MR images of asymptomatic volunteers: correlation with social and medical histories. Am J Roentgenol 1993;161:855–858
    PubMedWeb of Science
  18. ↵
    Bokura H, Kobayashi S, Yamaguchi S. Distinguishing silent lacunar infarction from enlarged Virchow-Robin spaces: a magnetic resonance imaging and pathological study. J Neurol 1998;245:116–22
    CrossRefPubMedWeb of Science
  19. ↵
    Mascalchi M, Salvi F, Gordano U, et al. Expanding lacunae causing triventricular hydrocephalus. Report of two cases. J Neurosurg 1999;91:669–674
    PubMed
  20. ↵
    Komiyama M, Yasui T, Izumi T. Magnet resonance imaging features of unusually dilated Virchow-Robin spaces—two case reports. Neurol Med Chir 1998;38:161–164
  21. ↵
    Sawada M, Nishi S, Hashimoto N. Unilateral appearance of markedly dilated Virchow-Robin spaces. Clin Radiol 1999;54:334–336
    CrossRefPubMed
  22. ↵
    Gerard G, Weisberg LA. MRI periventricular lesions in adults. Neurology 1986;36:998–1001
    Abstract/FREE Full Text
  23. ↵
    Drayer BP. Imaging of the aging brain. Part I. Normal findings Radiology 1988;166:785–796
  24. ↵
    Awad IA, Johnson PC, Spetzler RF, Hodak JA. Incidental subcortical lesions identified on magnetic resonance imaging in the elderly II. Postmortem pathological correlations. Stroke 1986;17:1090–1097
    Abstract/FREE Full Text
  25. Elster AD, Richardson DN. Focal high signal on MR scans of the midbrain caused by enlarged perivascular spaces: MR-pathologic correlation. AJR Am J Roentgenol 1991;156:157–160
    PubMed
  26. ↵
    Braffman BH, Zimmerman RA, Trojanowski JQ, Gonatas NK, Hickey WF, Schlaepfer WW. Brain MR: pathologic correlation with gross and histopathology. 1. Lacunar infarction and Virchow-Robin spaces. AJR Am J Roentgenol 1988;151:551–558
    PubMedWeb of Science
  27. ↵
    Adachi M, Hosoya T, Haku T, Yamaguchi K. Dilated Virchow-Robin spaces: MRI pathological study. Neuroradiology 1998;40:27–31
    CrossRefPubMed
  28. ↵
    Fazekas F, Kleinert R, Roob G, et al. Histopathologic analysis of foci of signal loss on gradient-echo T2*-weighted MR images in patients with spontaneous intracerebral hemorrhage: Evidence of microangiopathy-related microbleeds. AJNR Am J Neuroradiol 1999;20:637–642
    Abstract/FREE Full Text
  29. ↵
    Derouesné C, Gray F, Escourolle R, Castaigne P. ‘Expanding cerebral lacunae’ in a hypertensive patient with normal pressure hydrocephalus. Neuropath Appl Neurobiol 1987;13:309–320
    PubMed
  30. ↵
    Weller RO. Pathology of cerebrospinal fluid and interstitial fluid of the CNS: significance for Alzheimer disease, prion disorders and multiple sclerosis. J Neuropathol Exp Neurol 1998;57:885–894
    CrossRefPubMedWeb of Science
  31. ↵
    Weller RO, Massey A, Newman TA, Hutchings M, Kuo YM, Roher AE. Cerebral amyloid angiopathy: amyloid beta accumulates in putative interstitial fluid drainage pathways in Alzheimer’s disease. Am J Pathol 1998;153:725–733
    PubMedWeb of Science
  32. ↵
    Preston SD, Steart PV, Wilkinson A, Nicoll JAR, Weller RO. Capillary and arterial cerebral amyloid angiopathy in Alzheimer’s disease: defining the perivascular route for the elimination of amyloid beta from the human brain. Neuropathol Appl Neurobiol 2003;29:106–117
    CrossRefPubMedWeb of Science
  33. ↵
    Roher AE, Kuo YM, Esh C, et al. Cortical and Leptomeningeal Cerebro-Vascular Amyloid and White Matter Pathology in Alzheimer’s Disease. Molecular Medicine 2003;9:112–122
    PubMedWeb of Science
  34. ↵
    Sato N, Sze G, Awad I, et al. Parenchymal perianeurysmal cystic changes in the brain: Report of five cases. Radiology 200;215:229–233
  35. ↵
    Osborn AG. Brain Digital Teaching File. Salt Lake City: Advanced Medical Imaging Reference Systems;2003
PreviousNext
Back to top

In this issue

American Journal of Neuroradiology: 26 (2)
American Journal of Neuroradiology
Vol. 26, Issue 2
1 Feb 2005
  • Table of Contents
  • Index by author
Advertisement
Print
Download PDF
Email Article

Thank you for your interest in spreading the word on American Journal of Neuroradiology.

NOTE: We only request your email address so that the person you are recommending the page to knows that you wanted them to see it, and that it is not junk mail. We do not capture any email address.

Enter multiple addresses on separate lines or separate them with commas.
Giant Tumefactive Perivascular Spaces
(Your Name) has sent you a message from American Journal of Neuroradiology
(Your Name) thought you would like to see the American Journal of Neuroradiology web site.
CAPTCHA
This question is for testing whether or not you are a human visitor and to prevent automated spam submissions.
Cite this article
Karen L. Salzman, Anne G. Osborn, Paul House, J. Randy Jinkins, Adam Ditchfield, James A. Cooper, Roy O. Weller
Giant Tumefactive Perivascular Spaces
American Journal of Neuroradiology Feb 2005, 26 (2) 298-305;

Citation Manager Formats

  • BibTeX
  • Bookends
  • EasyBib
  • EndNote (tagged)
  • EndNote 8 (xml)
  • Medlars
  • Mendeley
  • Papers
  • RefWorks Tagged
  • Ref Manager
  • RIS
  • Zotero
0 Responses
Respond to this article
Share
Bookmark this article
Giant Tumefactive Perivascular Spaces
Karen L. Salzman, Anne G. Osborn, Paul House, J. Randy Jinkins, Adam Ditchfield, James A. Cooper, Roy O. Weller
American Journal of Neuroradiology Feb 2005, 26 (2) 298-305;
del.icio.us logo Twitter logo Facebook logo Mendeley logo
  • Tweet Widget
  • Facebook Like
  • Google Plus One

Jump to section

  • Article
    • Abstract
    • Methods
    • Results
    • Discussion
    • Conclusion
    • Footnotes
    • References
  • Figures & Data
  • Info & Metrics
  • Responses
  • References
  • PDF

Related Articles

  • No related articles found.
  • PubMed
  • Google Scholar

Cited By...

  • Giant Tumefactive Perivascular Spaces in a Patient Presenting With a First Seizure
  • Teaching NeuroImage: Traumatic Dissection of Lenticulostriate Arteries Within an Enlarged Perivascular Space
  • Quantitative MRI of Perivascular Spaces at 3T for Early Diagnosis of Mild Cognitive Impairment
  • Lacunar Infarcts, but Not Perivascular Spaces, Are Predictors of Cognitive Decline in Cerebral Small-Vessel Disease
  • Perivascular Spaces in Old Age: Assessment, Distribution, and Correlation with White Matter Hyperintensities
  • The structure of the perivascular compartment in the old canine brain: a case study
  • Tumefactive perivascular spaces: a rare incidental finding
  • Brain Perivascular Spaces as Biomarkers of Vascular Risk: Results from the Northern Manhattan Study
  • Hydrocephalus due to extreme dilation of Virchow-Robin spaces
  • Subcortical Cystic Lesions within the Anterior Superior Temporal Gyrus: A Newly Recognized Characteristic Location for Dilated Perivascular Spaces
  • Obstructive hydrocephalus due to cavernous dilation of Virchow-Robin spaces
  • Neuropathological Correlates of Temporal Pole White Matter Hyperintensities in CADASIL
  • Acute mesencephalic stroke associated with dilated cystic perivascular spaces
  • Crossref
  • Google Scholar

This article has not yet been cited by articles in journals that are participating in Crossref Cited-by Linking.

More in this TOC Section

  • Usefulness of Quantitative Susceptibility Mapping for the Diagnosis of Parkinson Disease
  • White Matter Alterations in the Brains of Patients with Active, Remitted, and Cured Cushing Syndrome: A DTI Study
  • Qualitative and Quantitative Analysis of MR Imaging Findings in Patients with Middle Cerebral Artery Stroke Implanted with Mesenchymal Stem Cells
Show more Brain

Similar Articles

Advertisement

Indexed Content

  • Current Issue
  • Accepted Manuscripts
  • Article Preview
  • Past Issues
  • Editorials
  • Editor's Choice
  • Fellows' Journal Club
  • Letters to the Editor
  • Video Articles

Cases

  • Case Collection
  • Archive - Case of the Week
  • Archive - Case of the Month
  • Archive - Classic Case

More from AJNR

  • Trainee Corner
  • Imaging Protocols
  • MRI Safety Corner
  • Book Reviews

Multimedia

  • AJNR Podcasts
  • AJNR Scantastics

Resources

  • Turnaround Time
  • Submit a Manuscript
  • Submit a Video Article
  • Submit an eLetter to the Editor/Response
  • Manuscript Submission Guidelines
  • Statistical Tips
  • Fast Publishing of Accepted Manuscripts
  • Graphical Abstract Preparation
  • Imaging Protocol Submission
  • Evidence-Based Medicine Level Guide
  • Publishing Checklists
  • Author Policies
  • Become a Reviewer/Academy of Reviewers
  • News and Updates

About Us

  • About AJNR
  • Editorial Board
  • Editorial Board Alumni
  • Alerts
  • Permissions
  • Not an AJNR Subscriber? Join Now
  • Advertise with Us
  • Librarian Resources
  • Feedback
  • Terms and Conditions
  • AJNR Editorial Board Alumni

American Society of Neuroradiology

  • Not an ASNR Member? Join Now

© 2025 by the American Society of Neuroradiology All rights, including for text and data mining, AI training, and similar technologies, are reserved.
Print ISSN: 0195-6108 Online ISSN: 1936-959X

Powered by HighWire