Skip to main content
Advertisement

Main menu

  • Home
  • Content
    • Current Issue
    • Accepted Manuscripts
    • Article Preview
    • Past Issue Archive
    • Video Articles
    • AJNR Case Collection
    • Case of the Week Archive
    • Case of the Month Archive
    • Classic Case Archive
  • Special Collections
    • AJNR Awards
    • Low-Field MRI
    • Alzheimer Disease
    • ASNR Foundation Special Collection
    • Photon-Counting CT
    • View All
  • Multimedia
    • AJNR Podcasts
    • AJNR SCANtastic
    • Trainee Corner
    • MRI Safety Corner
    • Imaging Protocols
  • For Authors
    • Submit a Manuscript
    • Submit a Video Article
    • Submit an eLetter to the Editor/Response
    • Manuscript Submission Guidelines
    • Statistical Tips
    • Fast Publishing of Accepted Manuscripts
    • Graphical Abstract Preparation
    • Imaging Protocol Submission
    • Author Policies
  • About Us
    • About AJNR
    • Editorial Board
    • Editorial Board Alumni
  • More
    • Become a Reviewer/Academy of Reviewers
    • Subscribers
    • Permissions
    • Alerts
    • Feedback
    • Advertisers
    • ASNR Home

User menu

  • Alerts
  • Log in

Search

  • Advanced search
American Journal of Neuroradiology
American Journal of Neuroradiology

American Journal of Neuroradiology

ASHNR American Society of Functional Neuroradiology ASHNR American Society of Pediatric Neuroradiology ASSR
  • Alerts
  • Log in

Advanced Search

  • Home
  • Content
    • Current Issue
    • Accepted Manuscripts
    • Article Preview
    • Past Issue Archive
    • Video Articles
    • AJNR Case Collection
    • Case of the Week Archive
    • Case of the Month Archive
    • Classic Case Archive
  • Special Collections
    • AJNR Awards
    • Low-Field MRI
    • Alzheimer Disease
    • ASNR Foundation Special Collection
    • Photon-Counting CT
    • View All
  • Multimedia
    • AJNR Podcasts
    • AJNR SCANtastic
    • Trainee Corner
    • MRI Safety Corner
    • Imaging Protocols
  • For Authors
    • Submit a Manuscript
    • Submit a Video Article
    • Submit an eLetter to the Editor/Response
    • Manuscript Submission Guidelines
    • Statistical Tips
    • Fast Publishing of Accepted Manuscripts
    • Graphical Abstract Preparation
    • Imaging Protocol Submission
    • Author Policies
  • About Us
    • About AJNR
    • Editorial Board
    • Editorial Board Alumni
  • More
    • Become a Reviewer/Academy of Reviewers
    • Subscribers
    • Permissions
    • Alerts
    • Feedback
    • Advertisers
    • ASNR Home
  • Follow AJNR on Twitter
  • Visit AJNR on Facebook
  • Follow AJNR on Instagram
  • Join AJNR on LinkedIn
  • RSS Feeds

AJNR Awards, New Junior Editors, and more. Read the latest AJNR updates

Research ArticleBRAIN

Correlation of Early Dynamic CT Perfusion Imaging with Whole-Brain MR Diffusion and Perfusion Imaging in Acute Hemispheric Stroke

James D. Eastwood, Michael H. Lev, Max Wintermark, Clemens Fitzek, Daniel P. Barboriak, David M. Delong, Ting-Yim Lee, Tarek Azhari, Michael Herzau, Vani R. Chilukuri and James M. Provenzale
American Journal of Neuroradiology October 2003, 24 (9) 1869-1875;
James D. Eastwood
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Michael H. Lev
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Max Wintermark
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Clemens Fitzek
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Daniel P. Barboriak
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
David M. Delong
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Ting-Yim Lee
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Tarek Azhari
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Michael Herzau
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Vani R. Chilukuri
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
James M. Provenzale
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
  • Article
  • Figures & Data
  • Info & Metrics
  • Responses
  • References
  • PDF
Loading

Article Figures & Data

Figures

  • Tables
  • Fig 1.
    • Download figure
    • Open in new tab
    • Download powerpoint
    Fig 1.

    54-year-old man with right hemiparesis.

    A–D, Diffusion-weighted images (b = 1000 s/mm2) illustrate volume of abnormality. Three-dimensional volume of abnormality was found by summing the areas of abnormality on each section (arrows) and multiplying by section thickness. The same approach was used to compute volumes of MR perfusion abnormality.

  • Fig 2.
    • Download figure
    • Open in new tab
    • Download powerpoint
    Fig 2.

    Scatterplot compares extents of CBF abnormality on single-slice CT perfusion scans with their corresponding extent of CBF abnormality on multislice MR perfusion images. Kendall τ b correlation coefficient for comparison of extent of CT-CBF with extent of MR-CBF was 0.60 (P = .003).

  • Fig 3.
    • Download figure
    • Open in new tab
    • Download powerpoint
    Fig 3.

    90-year-old woman with acute right hemiparesis and aphasia 2 hours before imaging.

    A, CT perfusion CBV map shows well-circumscribed area of very low CBV (arrows).

    B, MR perfusion CBV map. Correlation of volume of MR-CBV abnormality with area of CT-CBV abnormality approached statistical significance in our study.

    C, CT perfusion CBF map shows a larger abnormality than seen on the CBV map. CBF in the range of 0–10 mL/100 g/min is displayed as blue (arrows).

    D, MR perfusion CBF map with areas of low relative CBF (< 50%) displayed as blue (arrows). Good correlation was found in our study between extents of 2D CT-CBF abnormality and 3D MR-CBF abnormality.

    E, CT perfusion MTT map shows the largest extent of abnormality. Values of MTT greater than 6 seconds are displayed as red (arrows).

    F, MR MTT map. Good correlation was found in our study between 2D CT-MTT abnormalities and 3D MR-MTT abnormalities (arrows).

    G, Diffusion-weighted MR image (b = 1000 s/mm2) obtained 4 hours after symptom onset through the basal ganglia shows abnormality in the left frontal lobe (arrows). Good correlation was found in our study between extent of CT-CBV abnormality and extent of diffusion-weighted abnormality. Good correlation was also found with extents of MR-CBV and MR-MTT abnormalities.

Tables

  • Figures
  • Statistical correlation of extents of CT and MR perfusion abnormalities with extent of initial abnormality on diffusion-weighted images

    Perfusion ParameterCorrelation Coefficient*P Value
    CT-CBV0.47.02
    CT-CBF0.38.05
    CT-MTT0.32.11
    MR-CBV0.69.001
    MR-CBF0.41.04
    MR-MTT0.67.002
    • * Kendall τ b correlation coefficients.

PreviousNext
Back to top

In this issue

American Journal of Neuroradiology: 24 (9)
American Journal of Neuroradiology
Vol. 24, Issue 9
1 Oct 2003
  • Table of Contents
  • Index by author
Advertisement
Print
Download PDF
Email Article

Thank you for your interest in spreading the word on American Journal of Neuroradiology.

NOTE: We only request your email address so that the person you are recommending the page to knows that you wanted them to see it, and that it is not junk mail. We do not capture any email address.

Enter multiple addresses on separate lines or separate them with commas.
Correlation of Early Dynamic CT Perfusion Imaging with Whole-Brain MR Diffusion and Perfusion Imaging in Acute Hemispheric Stroke
(Your Name) has sent you a message from American Journal of Neuroradiology
(Your Name) thought you would like to see the American Journal of Neuroradiology web site.
CAPTCHA
This question is for testing whether or not you are a human visitor and to prevent automated spam submissions.
Cite this article
James D. Eastwood, Michael H. Lev, Max Wintermark, Clemens Fitzek, Daniel P. Barboriak, David M. Delong, Ting-Yim Lee, Tarek Azhari, Michael Herzau, Vani R. Chilukuri, James M. Provenzale
Correlation of Early Dynamic CT Perfusion Imaging with Whole-Brain MR Diffusion and Perfusion Imaging in Acute Hemispheric Stroke
American Journal of Neuroradiology Oct 2003, 24 (9) 1869-1875;

Citation Manager Formats

  • BibTeX
  • Bookends
  • EasyBib
  • EndNote (tagged)
  • EndNote 8 (xml)
  • Medlars
  • Mendeley
  • Papers
  • RefWorks Tagged
  • Ref Manager
  • RIS
  • Zotero
0 Responses
Respond to this article
Share
Bookmark this article
Correlation of Early Dynamic CT Perfusion Imaging with Whole-Brain MR Diffusion and Perfusion Imaging in Acute Hemispheric Stroke
James D. Eastwood, Michael H. Lev, Max Wintermark, Clemens Fitzek, Daniel P. Barboriak, David M. Delong, Ting-Yim Lee, Tarek Azhari, Michael Herzau, Vani R. Chilukuri, James M. Provenzale
American Journal of Neuroradiology Oct 2003, 24 (9) 1869-1875;
del.icio.us logo Twitter logo Facebook logo Mendeley logo
  • Tweet Widget
  • Facebook Like
  • Google Plus One

Jump to section

  • Article
    • Abstract
    • Methods
    • Image Analysis
    • Statistical Methods
    • Results
    • Discussion
    • Conclusion
    • Footnotes
    • References
  • Figures & Data
  • Info & Metrics
  • Responses
  • References
  • PDF

Related Articles

  • No related articles found.
  • PubMed
  • Google Scholar

Cited By...

  • Rescan Time Delays in Ischemic Stroke Imaging: A Retrospective Observation and Analysis of Causes and Clinical Impact
  • Early Basal Ganglia Hyperperfusion on CT Perfusion in Acute Ischemic Stroke: A Marker of Irreversible Damage?
  • Comparison of Computed Tomographic and Magnetic Resonance Perfusion Measurements in Acute Ischemic Stroke: Back-to-Back Quantitative Analysis
  • Diagnostic value of CT perfusion imaging for parotid neoplasms
  • Perfusion Deficits Detected by Arterial Spin-Labeling in Patients with TIA with Negative Diffusion and Vascular Imaging
  • CT perfusion-guided patient selection for endovascular recanalization in acute ischemic stroke: a multicenter study
  • Dramatically Reducing Imaging-to-Recanalization Time in Acute Ischemic Stroke: Making Choices
  • Cerebral Blood Flow Is the Optimal CT Perfusion Parameter for Assessing Infarct Core
  • Perfusion CT in Acute Ischemic Stroke: A Qualitative and Quantitative Comparison of Deconvolution and Maximum Slope Approach
  • Evaluation of CT Perfusion in the Setting of Cerebral Ischemia: Patterns and Pitfalls
  • A Comparison of Computed Tomography Perfusion-Guided and Time-Guided Endovascular Treatments for Patients With Acute Ischemic Stroke
  • Identification of Infarct Core and Penumbra in Acute Stroke Using CT Perfusion Source Images
  • Recommendations for Imaging of Acute Ischemic Stroke: A Scientific Statement From the American Heart Association
  • Perfusion CT in Patients with Acute Ischemic Stroke Treated with Intra-Arterial Thrombolysis: Predictive Value of Infarct Core Size on Clinical Outcome
  • Management of Stroke in Infants and Children: A Scientific Statement From a Special Writing Group of the American Heart Association Stroke Council and the Council on Cardiovascular Disease in the Young
  • Reproducibility of Quantitative CT Brain Perfusion Measurements in Patients with Symptomatic Unilateral Carotid Artery Stenosis
  • Identification of Penumbra and Infarct in Acute Ischemic Stroke Using Computed Tomography Perfusion-Derived Blood Flow and Blood Volume Measurements
  • Perfusion-CT Assessment of Infarct Core and Penumbra: Receiver Operating Characteristic Curve Analysis in 130 Patients Suspected of Acute Hemispheric Stroke
  • Visual evaluation of perfusion computed tomography in acute stroke accurately estimates infarct volume and tissue viability
  • Comparative Overview of Brain Perfusion Imaging Techniques
  • Comparison of Perfusion Computed Tomography and Computed Tomography Angiography Source Images With Perfusion-Weighted Imaging and Diffusion-Weighted Imaging in Patients With Acute Stroke of Less Than 6 Hours' Duration
  • Crossref
  • Google Scholar

This article has not yet been cited by articles in journals that are participating in Crossref Cited-by Linking.

More in this TOC Section

  • Enhanced Axonal Metabolism during Early Natalizumab Treatment in Relapsing-Remitting Multiple Sclerosis
  • SWI or T2*: Which MRI Sequence to Use in the Detection of Cerebral Microbleeds? The Karolinska Imaging Dementia Study
  • Progression of Microstructural Damage in Spinocerebellar Ataxia Type 2: A Longitudinal DTI Study
Show more BRAIN

Similar Articles

Advertisement

Indexed Content

  • Current Issue
  • Accepted Manuscripts
  • Article Preview
  • Past Issues
  • Editorials
  • Editor's Choice
  • Fellows' Journal Club
  • Letters to the Editor
  • Video Articles

Cases

  • Case Collection
  • Archive - Case of the Week
  • Archive - Case of the Month
  • Archive - Classic Case

More from AJNR

  • Trainee Corner
  • Imaging Protocols
  • MRI Safety Corner
  • Book Reviews

Multimedia

  • AJNR Podcasts
  • AJNR Scantastics

Resources

  • Turnaround Time
  • Submit a Manuscript
  • Submit a Video Article
  • Submit an eLetter to the Editor/Response
  • Manuscript Submission Guidelines
  • Statistical Tips
  • Fast Publishing of Accepted Manuscripts
  • Graphical Abstract Preparation
  • Imaging Protocol Submission
  • Evidence-Based Medicine Level Guide
  • Publishing Checklists
  • Author Policies
  • Become a Reviewer/Academy of Reviewers
  • News and Updates

About Us

  • About AJNR
  • Editorial Board
  • Editorial Board Alumni
  • Alerts
  • Permissions
  • Not an AJNR Subscriber? Join Now
  • Advertise with Us
  • Librarian Resources
  • Feedback
  • Terms and Conditions
  • AJNR Editorial Board Alumni

American Society of Neuroradiology

  • Not an ASNR Member? Join Now

© 2025 by the American Society of Neuroradiology All rights, including for text and data mining, AI training, and similar technologies, are reserved.
Print ISSN: 0195-6108 Online ISSN: 1936-959X

Powered by HighWire