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Improved Turnaround Times | Median time to first decision: 12 days

OtherNeurointervention

Successful Treatment of Cerebral Vasospasm by Use of Transdermal Nitroglycerin Ointment (Nitropaste)

Walter S. Lesley, Al Lazo, John C. Chaloupka and John B. Weigele
American Journal of Neuroradiology June 2003, 24 (6) 1234-1236;
Walter S. Lesley
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Al Lazo
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John C. Chaloupka
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John B. Weigele
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    Fig 1.

    Angiograms acquired in a 42-year-old female patient with a ruptured right supraclinoid ICA aneurysm.

    A, Angiogram obtained 10 days after subarachnoid hemorrhage reveals significant vasospasm of the M1 (small arrow) and A1 segments (arrow) of the middle cerebral artery and anterior cerebral artery, respectively. Note contrast material reflux into external carotid vasculature (double arrows). A filling defect of the internal carotid artery can be explained by aneurysm clip artifact (asterisk).

    B, Angiogram obtained 7 minutes after applying 2 inches of Nitropaste to the upper chest shows an increase in the diameter of the distal internal carotid artery and M1 and A1 (arrow) segments, including notably improved distal flow in the anterior cerebral artery branches. Note the lack of contrast material reflux into the external carotid vasculature.

    C, Final angiogram obtained after reveals caliber normalization of the supraclinoid ICA and proximal anterior and middle cerebral arteries.

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    Fig 2.

    Angiograms obtained in a 45-year-old female patient with a ruptured basilar tip aneurysm.

    A, Angiogram acquired in a patient with mild vasospasm; transcranial sonography revealed subarachnoid hemorrhage 3 days earlier.

    B, Twenty-six minutes after applying 3 inches of Nitropaste to the upper chest, the supraclinoid internal carotid artery (open arrow), anterior cerebral artery (arrow), and middle cerebral artery (curved arrow) have definitely increased in diameter.

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    Fig 3.

    Angiograms acquired in a 55-year-old patient with a ruptured right paraophthalmic ICA aneurysm.

    A, Angiogram, frontal-right projection,of the internal carotid artery depicts mild vasospasm of the anterior and middle cerebral vasculature secondary to a ruptured, and subsequently coiled, paraophthalmic aneurysm.

    B, Repeat angiogram obtained 27 minutes after application of transdermal Nitropaste reveals improved vasospasm in the anterior cerebral artery and middle cerebral artery territories (arrows).

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American Journal of Neuroradiology: 24 (6)
American Journal of Neuroradiology
Vol. 24, Issue 6
1 Jun 2003
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Walter S. Lesley, Al Lazo, John C. Chaloupka, John B. Weigele
Successful Treatment of Cerebral Vasospasm by Use of Transdermal Nitroglycerin Ointment (Nitropaste)
American Journal of Neuroradiology Jun 2003, 24 (6) 1234-1236;

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Successful Treatment of Cerebral Vasospasm by Use of Transdermal Nitroglycerin Ointment (Nitropaste)
Walter S. Lesley, Al Lazo, John C. Chaloupka, John B. Weigele
American Journal of Neuroradiology Jun 2003, 24 (6) 1234-1236;
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