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Improved Turnaround Times | Median time to first decision: 12 days

Research ArticleBrain

Abnormal Magnetization Transfer Ratios in Normal-appearing White Matter on Conventional MR Images of Patients with Occlusive Cerebrovascular Disease

Hirotsugu Kado, Hirohiko Kimura, Tatsuro Tsuchida, Yoshiharu Yonekura, Tomoo Tokime, Yasuhiko Tokuriki and Harumi Itoh
American Journal of Neuroradiology May 2001, 22 (5) 922-927;
Hirotsugu Kado
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Hirohiko Kimura
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Tatsuro Tsuchida
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Yoshiharu Yonekura
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Tomoo Tokime
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Yasuhiko Tokuriki
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Harumi Itoh
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    fig 1.

    The location of selected ROIs. Four ROIs were selected in the lesional deep white matter and three in the lesional centrum semiovale. Although this figure shows that ROIs were placed only on MTR maps and CBF images, actually the same ROIs were selected on T2-weighted images and other PET scans (CMRO2 and OEF images). PET scans were registered to the MR images of each subject. Circular ROIs were placed in right and left symmetrical locations, so that the AI could be calculated

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    fig 2.

    2D plot of MTR and rCMRO2 values with an AI from groups 0, 1, and 2. The correlation coefficient was .85 (P = .001)

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    TABLE 1:

    Demographic and clinical data for 13 patient with unilateral severe stenosis of the internal carotid artery (ICA)

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    TABLE 2:

    Mean values of absolute regional cerebral blood flow (rCBF), absolute regional cerebral metabolic rate of oxygen (rCMRO2), absolute regional oxygen extraction fraction (rOEF), normalized T2-weighted images, and rOEF asymmetric index (AI) from the lesional side in 13 patients with unilateral severe stenosis of the internal carotid artery by group*

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American Journal of Neuroradiology
Vol. 22, Issue 5
1 May 2001
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Abnormal Magnetization Transfer Ratios in Normal-appearing White Matter on Conventional MR Images of Patients with Occlusive Cerebrovascular Disease
Hirotsugu Kado, Hirohiko Kimura, Tatsuro Tsuchida, Yoshiharu Yonekura, Tomoo Tokime, Yasuhiko Tokuriki, Harumi Itoh
American Journal of Neuroradiology May 2001, 22 (5) 922-927;
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  • Extent of Microstructural Tissue Damage Correlates with Hemodynamic Failure in High-Grade Carotid Occlusive Disease: An MRI Study Using Quantitative T2 and DSC Perfusion
  • Magnetization Transfer Imaging Shows Tissue Abnormalities in the Reversible Penumbra
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Cite this article
Hirotsugu Kado, Hirohiko Kimura, Tatsuro Tsuchida, Yoshiharu Yonekura, Tomoo Tokime, Yasuhiko Tokuriki, Harumi Itoh
Abnormal Magnetization Transfer Ratios in Normal-appearing White Matter on Conventional MR Images of Patients with Occlusive Cerebrovascular Disease
American Journal of Neuroradiology May 2001, 22 (5) 922-927;

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