Skip to main content
Advertisement

Main menu

  • Home
  • Content
    • Current Issue
    • Accepted Manuscripts
    • Article Preview
    • Past Issue Archive
    • Video Articles
    • AJNR Case Collection
    • Case of the Week Archive
    • Case of the Month Archive
    • Classic Case Archive
  • Special Collections
    • Advancing NeuroMRI with High-Relaxivity Contrast Agents
    • AJNR Awards
    • Low-Field MRI
    • Alzheimer Disease
    • ASNR Foundation Special Collection
    • Photon-Counting CT
    • View All
  • Multimedia
    • AJNR Podcasts
    • AJNR SCANtastic
    • Trainee Corner
    • MRI Safety Corner
    • Imaging Protocols
  • For Authors
    • Submit a Manuscript
    • Submit a Video Article
    • Submit an eLetter to the Editor/Response
    • Manuscript Submission Guidelines
    • Statistical Tips
    • Fast Publishing of Accepted Manuscripts
    • Graphical Abstract Preparation
    • Imaging Protocol Submission
    • Author Policies
  • About Us
    • About AJNR
    • Editorial Board
    • Editorial Board Alumni
  • More
    • Become a Reviewer/Academy of Reviewers
    • Subscribers
    • Permissions
    • Alerts
    • Feedback
    • Advertisers
    • ASNR Home

User menu

  • Alerts
  • Log in

Search

  • Advanced search
American Journal of Neuroradiology
American Journal of Neuroradiology

American Journal of Neuroradiology

ASHNR American Society of Functional Neuroradiology ASHNR American Society of Pediatric Neuroradiology ASSR
  • Alerts
  • Log in

Advanced Search

  • Home
  • Content
    • Current Issue
    • Accepted Manuscripts
    • Article Preview
    • Past Issue Archive
    • Video Articles
    • AJNR Case Collection
    • Case of the Week Archive
    • Case of the Month Archive
    • Classic Case Archive
  • Special Collections
    • Advancing NeuroMRI with High-Relaxivity Contrast Agents
    • AJNR Awards
    • Low-Field MRI
    • Alzheimer Disease
    • ASNR Foundation Special Collection
    • Photon-Counting CT
    • View All
  • Multimedia
    • AJNR Podcasts
    • AJNR SCANtastic
    • Trainee Corner
    • MRI Safety Corner
    • Imaging Protocols
  • For Authors
    • Submit a Manuscript
    • Submit a Video Article
    • Submit an eLetter to the Editor/Response
    • Manuscript Submission Guidelines
    • Statistical Tips
    • Fast Publishing of Accepted Manuscripts
    • Graphical Abstract Preparation
    • Imaging Protocol Submission
    • Author Policies
  • About Us
    • About AJNR
    • Editorial Board
    • Editorial Board Alumni
  • More
    • Become a Reviewer/Academy of Reviewers
    • Subscribers
    • Permissions
    • Alerts
    • Feedback
    • Advertisers
    • ASNR Home
  • Follow AJNR on Twitter
  • Visit AJNR on Facebook
  • Follow AJNR on Instagram
  • Join AJNR on LinkedIn
  • RSS Feeds

AJNR Awards, New Junior Editors, and more. Read the latest AJNR updates


Improved Turnaround Times | Median time to first decision: 12 days

Research ArticleBrain

Highly Active Antiretroviral Therapy for Patients with AIDS Dementia Complex: Effect on MR Imaging Findings and Clinical Course

Majda M. Thurnher, Erwin G. Schindler, Siegfried A. Thurnher, Heidemarie Pernerstorfer-Schön, Christina Kleibl-Popov and Armin Rieger
American Journal of Neuroradiology April 2000, 21 (4) 670-678;
Majda M. Thurnher
aFrom the Departments of Radiology (M.M.T., E.G.S., S.A.T.) and Dermatology (H.P-S., C.K-P., A.R.), University of Vienna, Austria.
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Erwin G. Schindler
aFrom the Departments of Radiology (M.M.T., E.G.S., S.A.T.) and Dermatology (H.P-S., C.K-P., A.R.), University of Vienna, Austria.
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Siegfried A. Thurnher
aFrom the Departments of Radiology (M.M.T., E.G.S., S.A.T.) and Dermatology (H.P-S., C.K-P., A.R.), University of Vienna, Austria.
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Heidemarie Pernerstorfer-Schön
aFrom the Departments of Radiology (M.M.T., E.G.S., S.A.T.) and Dermatology (H.P-S., C.K-P., A.R.), University of Vienna, Austria.
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Christina Kleibl-Popov
aFrom the Departments of Radiology (M.M.T., E.G.S., S.A.T.) and Dermatology (H.P-S., C.K-P., A.R.), University of Vienna, Austria.
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Armin Rieger
aFrom the Departments of Radiology (M.M.T., E.G.S., S.A.T.) and Dermatology (H.P-S., C.K-P., A.R.), University of Vienna, Austria.
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
  • Article
  • Figures & Data
  • Info & Metrics
  • Responses
  • References
  • PDF
Loading

References

  1. ↵
    Budka H, Constanzi G, Cristina S, et al. Brain pathology induced by infection with the human immunodeficiency virus (HIV): a histological, immunohistochemical, and electron microscopical study of 100 autopsy cases. Acta Neuropathol 1987;75:185-198
    CrossRefPubMedWeb of Science
  2. Budka H. Human immunodeficiency virus (HIV)-induced disease of the central nervous system: pathology and implications for pathogenesis. Acta Neuropathol 1989;77:225-236
    CrossRefPubMed
  3. ↵
    Post MJD, Tate LG, Quencer RM, et al. CT, MR, and pathology in HIV encephalitis and meningitis. AJR Am J Roentgenol 1988;151:373-380
    PubMedWeb of Science
  4. ↵
    Broderick DF, Wippold FJ II, Clifford DB, Kido D, Wilson BS. White matter lesions and cerebral atrophy on MR images in patients with and without AIDS dementia complex. AJR Am J Roentgenol 1993;161:177-181
    CrossRefPubMed
  5. ↵
    Olsen WL, Longo FM, Mills CM, Norman D. White matter disease in AIDS: findings at MR imaging. Radiology 1988;169:445-448
    CrossRefPubMedWeb of Science
  6. Hawkins CP, McLaughlin JE, Kendall BE, McDonald WI. Pathological findings correlated with MRI in HIV infection. Neuroradiology 1993;35:264-268
    CrossRefPubMedWeb of Science
  7. Grassi MP, Clerici F, Boldorini R, et al. HIV encephalitis and HIV leukoencephalopathy are associated with distinct clinical and radiological subtypes of the AIDS dementia complex. AIDS 1997;11:690-691
    PubMed
  8. ↵
    Carpenter CJ, Fischl MA, Hammer SM, et al. Antiretroviral therapy for HIV infection in 1996: recommendations of an international panel. JAMA 1996;276:146-154
    CrossRefPubMedWeb of Science
  9. Barry M, Gibbons S, Back D, Mulcahy F. Protease inhibitors in patients with HIV disease. Clin Pharmacokinet 1997;32:194-209
    CrossRefPubMedWeb of Science
  10. Noble S, Faulds D, Saquinavir A review of its pharmacology and clinical potential in the management of HIV infection. Drugs 1996;52:93-112
    CrossRefPubMedWeb of Science
  11. Deeks SG, Smith M, Holodniy M, Kahn J. HIV-1 protease inhibitors: a review for clinicians. JAMA 1997;277:145-153
    CrossRefPubMedWeb of Science
  12. Markowitz M, Saag M, Powderly WG, et al. A preliminary study of ritonavir, an inhibitor of HIV-1 protease, to treat HIV-1 infection. N Engl J Med 1995;333:1534-1539
    CrossRefPubMedWeb of Science
  13. Mileno MD, Tashima K, Farrar D, Elliot BD, Rich JD, Flanigan TP. Resolution of AIDS-related opportunistic infections with addition of protease inhibitor treatment. Presented at the 4th Conference on Retroviruses and Opportunistic Infections, 1997
  14. ↵
    Filippi CG, Sze G, Farber SJ, Shahmanesh M, Selwyn PA. Regression of HIV encephalopathy and basal ganglia signal intensity abnormality at MR imaging in patients with AIDS after the initiation of protease inhibitor therapy. Radiology 1998;206:491-498
    PubMedWeb of Science
  15. ↵
    Navia BA, Jordan BD, Price RW. The AIDS dementia complex, I: clinical features. Ann Neurol 1986;19:517-524
    CrossRefPubMedWeb of Science
  16. ↵
    Albert ML, Feldman RG, Willis AL. The “subcortical dementia” of progressive supranuclear palsy. J Neurol Neurosurg Psychiatry 1974;37:121-130
    Abstract/FREE Full Text
  17. ↵
    Poutiainen E, Haltia M, Elovaara I, Lähdevirta J, Iivanainen M. Dementia associated with human immunodeficiency virus: subcortical or cortical? Acta Psychiatry Scand 1991;83:297-301
    CrossRefPubMed
  18. Arendt G, Hefter H, Neuen-Jacob E, et al. Electrophysiological motor testing, MRI findings and clinical course in AIDS patients with dementia. J Neurol 1993;240:439-445
    CrossRefPubMedWeb of Science
  19. ↵
    Glass JD, Wesselingh SL, Selnes OA, McArthur JC. Clinical-neuropathologic correlation in HIV-associated dementia. Neurology 1993;43:2230-2237
    Abstract/FREE Full Text
  20. Bencherif B, Rottenberg DA. Neuroimaging of the AIDS dementia complex. AIDS 1998;12:233-244
    PubMed
  21. Chrysikopoulos HS, Press GA, Grafe MR, Hesselink JR, Wiley CA. Encephalitis caused by human immunodeficiency virus: CT and MR imaging manifestations with clinical and pathologic correlation. Radiology 1990;175:185-191
    CrossRefPubMedWeb of Science
  22. Raininko R, Elovaara I, Virta A, Valanne L, Haltia M, Valle SL. Radiological study of the brain at various stages of human immunodeficiency virus infection: early development of brain atrophy. Neuroradiology 1992;34:190-196
    CrossRefPubMedWeb of Science
  23. Grafe MR, Press GA, Berthoty DP, Hesselink JR, Wiley CA. Abnormalities of the brain in AIDS patients: correlation of post mortem MR findings with neuropathology. AJNR Am J Neuroradiol 1990;11:905-911
    Abstract/FREE Full Text
  24. ↵
    Brouwers P, Hendricks M, Lietzau JA, et al. Effect of combination therapy with zidovudine and didanosine on neuropsychological functioning in patients with symptomatic HIV disease: a comparison of simultaneous and altering regimens. AIDS 1997;11:59-66
    CrossRefPubMedWeb of Science
  25. Vago L, Castagna A, Lazzarin A, Cinque P, Trabattoni G, Constanzi G. Zidovudine and frequency of HIV-induced diffuse leukoencephalopathy. Lancet 1991;337:1488
    PubMedWeb of Science
  26. Sidtis J, Gatsonis C, Price R, et al. Zidovudine treatment of the AIDS dementia complex: results of a placebo-controlled trial. Ann Neurol 1993;33:343-349
    CrossRefPubMedWeb of Science
  27. Tozzi V, Narciso P, Galgani S, et al. Effects of zidovudine in 30 patients with mild to end-stage AIDS dementia complex. AIDS 1993;7:683-692
    PubMedWeb of Science
  28. ↵
    Post MJD, Levin BE, Berger JR, Duncan R, Quencer RM, Calabro G. Sequential cranial MR findings of asymptomatic and neurologically symptomatic HIV+ subjects. AJNR Am J Neuroradiol 1992;13:359-370
    Abstract/FREE Full Text
  29. ↵
    Bartlett J. 1998; Medical Management of HIV Infection.. Baltimore: Johns Hopkins University Press; 1998
  30. ↵
    Sactor NC. Advances in the treatment of HIV dementia. AIDS Reader 1999;9:57-60
    PubMed
  31. ↵
    Gendelman HE, Zheng J, Coulter CL, et al. Suppression of inflammatory neurotoxins by highly active antiretroviral therapy in human immunodeficiency virus–associated dementia. J Infect Dis 1998;178:1000-1007
    CrossRefPubMedWeb of Science
  32. Sactor N, Skolasky R, Esposito D, et al. Combination therapy including protease inhibitors improves psychomotor speed performance in HIV infection. Neurology 1998;50:A248-A249
  33. Sactor N, Skolasky R, Lyles R, et al. Highly active antiretroviral therapy (HAART) improves cognitive impairment in HIV+ homosexual men. J Neurovirol 1998;4:365
  34. ↵
    Murray JS, Elashoff MR, Iacono-Connors LC, Cvetkovich TA, Struble KA. The use of HIV RNA as a study endpoint in efficacy trials of antiretroviral drugs. AIDS 1999;13:797-804
    CrossRefPubMedWeb of Science
PreviousNext
Back to top

In this issue

American Journal of Neuroradiology
Vol. 21, Issue 4
1 Apr 2000
  • Table of Contents
  • Index by author
Advertisement
Print
Download PDF
Email Article

Thank you for your interest in spreading the word on American Journal of Neuroradiology.

NOTE: We only request your email address so that the person you are recommending the page to knows that you wanted them to see it, and that it is not junk mail. We do not capture any email address.

Enter multiple addresses on separate lines or separate them with commas.
Highly Active Antiretroviral Therapy for Patients with AIDS Dementia Complex: Effect on MR Imaging Findings and Clinical Course
(Your Name) has sent you a message from American Journal of Neuroradiology
(Your Name) thought you would like to see the American Journal of Neuroradiology web site.
CAPTCHA
This question is for testing whether or not you are a human visitor and to prevent automated spam submissions.
Cite this article
Majda M. Thurnher, Erwin G. Schindler, Siegfried A. Thurnher, Heidemarie Pernerstorfer-Schön, Christina Kleibl-Popov, Armin Rieger
Highly Active Antiretroviral Therapy for Patients with AIDS Dementia Complex: Effect on MR Imaging Findings and Clinical Course
American Journal of Neuroradiology Apr 2000, 21 (4) 670-678;

Citation Manager Formats

  • BibTeX
  • Bookends
  • EasyBib
  • EndNote (tagged)
  • EndNote 8 (xml)
  • Medlars
  • Mendeley
  • Papers
  • RefWorks Tagged
  • Ref Manager
  • RIS
  • Zotero
0 Responses
Respond to this article
Share
Bookmark this article
Highly Active Antiretroviral Therapy for Patients with AIDS Dementia Complex: Effect on MR Imaging Findings and Clinical Course
Majda M. Thurnher, Erwin G. Schindler, Siegfried A. Thurnher, Heidemarie Pernerstorfer-Schön, Christina Kleibl-Popov, Armin Rieger
American Journal of Neuroradiology Apr 2000, 21 (4) 670-678;
del.icio.us logo Twitter logo Facebook logo Mendeley logo
  • Tweet Widget
  • Facebook Like
  • Google Plus One

Jump to section

  • Article
    • Abstract
    • Methods
    • Results
    • Discussion
    • Conclusion
    • Footnotes
    • References
  • Figures & Data
  • Info & Metrics
  • Responses
  • References
  • PDF

Related Articles

  • No related articles found.
  • PubMed
  • Google Scholar

Cited By...

  • Association of White Matter Hyperintensities With HIV Status and Vascular Risk Factors
  • CNS-Immune Reconstitution Inflammatory Syndrome in the Setting of HIV Infection, Part 2: Discussion of Neuro-Immune Reconstitution Inflammatory Syndrome with and without Other Pathogens
  • Imaging evaluation of demyelinating processes of the central nervous system
  • Viruses and the brain: from inflammation to dementia
  • Crossref
  • Google Scholar

This article has not yet been cited by articles in journals that are participating in Crossref Cited-by Linking.

More in this TOC Section

  • Usefulness of Quantitative Susceptibility Mapping for the Diagnosis of Parkinson Disease
  • White Matter Alterations in the Brains of Patients with Active, Remitted, and Cured Cushing Syndrome: A DTI Study
  • Qualitative and Quantitative Analysis of MR Imaging Findings in Patients with Middle Cerebral Artery Stroke Implanted with Mesenchymal Stem Cells
Show more Brain

Similar Articles

Advertisement

Indexed Content

  • Current Issue
  • Accepted Manuscripts
  • Article Preview
  • Past Issues
  • Editorials
  • Editor's Choice
  • Fellows' Journal Club
  • Letters to the Editor
  • Video Articles

Cases

  • Case Collection
  • Archive - Case of the Week
  • Archive - Case of the Month
  • Archive - Classic Case

More from AJNR

  • Trainee Corner
  • Imaging Protocols
  • MRI Safety Corner
  • Book Reviews

Multimedia

  • AJNR Podcasts
  • AJNR Scantastics

Resources

  • Turnaround Time
  • Submit a Manuscript
  • Submit a Video Article
  • Submit an eLetter to the Editor/Response
  • Manuscript Submission Guidelines
  • Statistical Tips
  • Fast Publishing of Accepted Manuscripts
  • Graphical Abstract Preparation
  • Imaging Protocol Submission
  • Evidence-Based Medicine Level Guide
  • Publishing Checklists
  • Author Policies
  • Become a Reviewer/Academy of Reviewers
  • News and Updates

About Us

  • About AJNR
  • Editorial Board
  • Editorial Board Alumni
  • Alerts
  • Permissions
  • Not an AJNR Subscriber? Join Now
  • Advertise with Us
  • Librarian Resources
  • Feedback
  • Terms and Conditions
  • AJNR Editorial Board Alumni

American Society of Neuroradiology

  • Not an ASNR Member? Join Now

© 2025 by the American Society of Neuroradiology All rights, including for text and data mining, AI training, and similar technologies, are reserved.
Print ISSN: 0195-6108 Online ISSN: 1936-959X

Powered by HighWire