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Research ArticleBRAIN

MR Imaging of Acute Coccidioidal Meningitis

William K. Erly, Richard J. Bellon, Joachim F. Seeger and Raymond F. Carmody
American Journal of Neuroradiology March 1999, 20 (3) 509-514;
William K. Erly
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Richard J. Bellon
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Joachim F. Seeger
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Raymond F. Carmody
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    fig 1.

    Life cycle of Coccidioides immitis.

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    fig 2.

    Case 7: 28-year-old woman.

    A, Coronal contrast-enhanced T1-weighted image shows diffuse abnormal meningeal enhancement (arrow) along the course of the middle and anterior cerebral arteries. A shunt catheter (arrowheads) has been placed for acute hydrocephalus.

    B, Axial T2-weighted image shows edema in the deep nuclei bilaterally (arrows). This is believed to represent areas of infarction/ischemia consequent to coccidioidal vasculitis.

    fig 3. Case 1: 36-year-old man. Findings on initial study were normal (not shown). Follow-up axial contrast-enhanced T1-weighted image 2 months later shows discrete nodules of abnormal enhancement (arrow) in the perimesencephalic cistern.

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    fig 4.

    Case 2: 22-year-old woman with disease progression.

    A, Initial coronal contrast-enhanced T1-weighted MR image with focal enhancement in the left sylvian fissure (arrow).

    B, Follow-up study 2 weeks later shows a new small focus of abnormal meningeal enhancement (arrow) on the medial aspect of the uncus.

    C and D, Another week later, there is marked progression of disease to diffusely involve the basilar cisterns (arrows) as well as the course of the middle cerebral arteries (arrowheads).

  • fig 5.
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    fig 5.

    Case 4: 70-year-old man.

    A, Unenhanced T1-weighted image shows abnormal soft-tissue mass in the ambient cistern (arrows).

    B, Dense enhancement (arrowheads) is seen after administration of gadolinium chelate.

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    fig 6.

    Case 10: Low signal on T2-weighted images.

    A, Axial T2-weighted image shows decreased signal (arrow) in the prepontine cistern.

    B, Contrast-enhanced T1-weighted sequence shows marked enhancement (arrow) of the same area.

Tables

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    TABLE 1:

    Findings in 14 patients with acute coccidioidal meningitis

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    TABLE 2:

    Summary of imaging findings in 14 patients at presentation (one patient had an initial CT scan)

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    TABLE 3:

    Summary of findings in 13 patients on the first abnormal MR examination (no follow-up examination was available for one patient with an initially normal study)

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American Journal of Neuroradiology
Vol. 20, Issue 3
1 Mar 1999
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Cite this article
William K. Erly, Richard J. Bellon, Joachim F. Seeger, Raymond F. Carmody
MR Imaging of Acute Coccidioidal Meningitis
American Journal of Neuroradiology Mar 1999, 20 (3) 509-514;

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MR Imaging of Acute Coccidioidal Meningitis
William K. Erly, Richard J. Bellon, Joachim F. Seeger, Raymond F. Carmody
American Journal of Neuroradiology Mar 1999, 20 (3) 509-514;
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