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482 COVID-19 in patients with lung cancer receiving immunotherapy. A report from an spanish academic center
David Viñal, Laura Gutierrez, Julia Villamayor, Oliver Higuera, Dario Sanchez Cabrero, Javier De Castro

Journal for ImmunoTherapy of Cancer Nov 2020, 8 (Suppl 3) A298-A299; DOI: 10.1136/jitc-2020-SITC2020.0482
483 Association of COVID-19 inflammation with activation of the C5a-C5aR1 axis
Olivier Demaria, Julien Carvelli, Nassima Chouaki Benmansour, Joanna Fares, Luciana Batista, Marie-Laure Thibult, Ariane Morel, Sabrina Carpentier, Romain Remark, Agnes Represa, Frederic Vely, Mikael Ebbo, Nicolas Schleinitz, Robert Zerbib, Yannis Morel, Eric Vivier, Olivier Demaria

Journal for ImmunoTherapy of Cancer Nov 2020, 8 (Suppl 3) A299; DOI: 10.1136/jitc-2020-SITC2020.0483
48 Advances in multiplexed ion beam imaging (MIBI) for immune profiling of the tumor microenvironment
Jason Ptacek, Felipe Geyer, Andre Mignault, James Deeds, Jimmy Giedt, Jane Gu, Margaret McLaughlin, Yari Sigal, Jay Tarolli, Murat Aksoy, Yi Zhang, Monirath Hav, Rachel Finck, Jessica Finn

Journal for ImmunoTherapy of Cancer Nov 2020, 8 (Suppl 3) A30; DOI: 10.1136/jitc-2020-SITC2020.0048
275 Translational endpoints associated with STK11 mutations in patients with non-squamous NSCLC
Song Wu, Nathan Standifer, Melissa de los Reyes, Micheal Oberst, Rajv Raja, Carl Barrett, Maria Ascierto

Journal for ImmunoTherapy of Cancer Nov 2020, 8 (Suppl 3) A300; DOI: 10.1136/jitc-2020-SITC2020.0275
487 Reasons for not testing for biomarkers in non-small cell lung cancer: a regional comparison of patients in the US and Europe
Nikita Sharma, Mahaletchumy Krishnam, Ayse Levent

Journal for ImmunoTherapy of Cancer Nov 2020, 8 (Suppl 3) A301; DOI: 10.1136/jitc-2020-SITC2020.0487
488 The impact of education on novel concepts in metastatic melanoma: triplet therapy
Kinjal Parikh, Sara Fagerlie, Patrick Kugel, Richard Caracio, Ryan Sullivan

Journal for ImmunoTherapy of Cancer Nov 2020, 8 (Suppl 3) A301-A302; DOI: 10.1136/jitc-2020-SITC2020.0488
489 The impact of education on novel concepts in adjuvant melanoma: a closer look at high risk stage II disease
Kinjal Parikh, Charlotte Warren, Emily Van Laar, Jason Luke

Journal for ImmunoTherapy of Cancer Nov 2020, 8 (Suppl 3) A302; DOI: 10.1136/jitc-2020-SITC2020.0489
492 Integration of high dimensional datasets in an immunocompetent mammary mouse model reveals pathways of tolerance and resistance to immune checkpoint blockade
Lin Ma, Jian-Hua Mao, Mary Helen Barcellos-Hoff, Jade Moore

Journal for ImmunoTherapy of Cancer Nov 2020, 8 (Suppl 3) A304; DOI: 10.1136/jitc-2020-SITC2020.0492
500 P2RX7 agonist treatment boosts the ability of IL-12-activated CD8+ T cells to infiltrate and control murine melanoma
Kelsey Wanhainen, Stephen Jameson, Henrique Borges Da Silva

Journal for ImmunoTherapy of Cancer Nov 2020, 8 (Suppl 3) A307-A308; DOI: 10.1136/jitc-2020-SITC2020.0500
503 Tumor infiltrating lymphocytes in soft tissue sarcomas upregulate the exhaustion marker TIGIT and are reinvigorated by IL-15 stimulation and TIGIT blockade
Sean Judge, Morgan Darrow, Steven Thorpe, Alicia Gingrich, Edmond O’Donnell, Alyssa Bellini, Ian Sturgill, Logan Vick, Cordelia Dunai, Kevin Stoffel, Yue Lyu, Shuai Chen, May Cho, Robert Rebhun, Arta Monjazeb, William Murphy, Robert Canter

Journal for ImmunoTherapy of Cancer Nov 2020, 8 (Suppl 3) A309; DOI: 10.1136/jitc-2020-SITC2020.0503

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