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1027 scTCR/RNA-Seq identifiy two exhausted T cell subsets in neoantigen-specific CD8⁺ T cells
Koji Nagaoka, Yukari Kobayashi, Hiroto Katoh, Tomoko Saito, Yoshikazu Totsuka, Kazuyoshi Takeda, Shumpei Ishikawa, Kazuhiro Kakimi

Journal for ImmunoTherapy of Cancer Nov 2023, 11 (Suppl 1) A1135; DOI: 10.1136/jitc-2023-SITC2023.1027
1028 Ex vivo chemotherapy resistance of metabolically reprogrammed autologous Th1/Tc1 cells (RAPA-201): Towards the clinical translation of immune-sparing host conditioning
Jee Hyun Park, Deborah Glass, Martin Gutierrez, Tania Felizardo, Daniel H Fowler

Journal for ImmunoTherapy of Cancer Nov 2023, 11 (Suppl 1) A1136; DOI: 10.1136/jitc-2023-SITC2023.1028
1029 T cell receptor diversity analysis of in vitro-expanded T cells against IDO1 and PD-L1-derived peptides
Preeyam Patel, Marcos Iglesias, Qin Tang, Megan Biller, Alireza Alavi, Ayako Pedersen

Journal for ImmunoTherapy of Cancer Nov 2023, 11 (Suppl 1) A1137; DOI: 10.1136/jitc-2023-SITC2023.1029
1030 Peripheral immunological dynamics of response in pancreatic cancer treated with immune checkpoint inhibitors
Mario Presti, Arianna Draghi, Christopher A Chamberlain, Shawez Khan, Marta Sanchez Sanchez, Inge Marie Svane, Inna M Chen, Marco Donia

Journal for ImmunoTherapy of Cancer Nov 2023, 11 (Suppl 1) A1138; DOI: 10.1136/jitc-2023-SITC2023.1030
1032 Early remodelling of CD4 T cell differentiation in lung squamous carcinogenesis
Teerapon Sahwangarrom, Claudia Peinador Marin, Sam Gamble, Zoe Whiteman, Seng Ung, Lukas Kalinke, Ahmed Alhendi, Adam Pennycuick, Sandra Gomez Lopez, Andrei Enica, Amber Rogers, Kate Davies, Kane Foster, Amalie Kai Bentzen, Moritz Przybilla, Kate Gowers, Vitor Teixeira, Peter Campbell, Bart Vanhaesebroeck, Sam Janes, James L Reading

Journal for ImmunoTherapy of Cancer Nov 2023, 11 (Suppl 1) A1139; DOI: 10.1136/jitc-2023-SITC2023.1032
1033 ID3 and c-Kit define the stem-like potential of T cells and their response to chronic infection and cancer
Amania A Sheikh, Dane M Newman, Ricky W Johnstone, Axel Kallies, Daniel Utzschneider

Journal for ImmunoTherapy of Cancer Nov 2023, 11 (Suppl 1) A1140; DOI: 10.1136/jitc-2023-SITC2023.1033
1034 Identification of a potentially novel regulatory axis involving KIR+CD8+ HLA-E/VL9 tetramer+ T cells and HLA-E^hi cTFH
Marcia Stickler, Tracey Chan, Seonhui Shim, Maria Pokrovskii, Kenneth Finn, Chirag Patel, Andrew Nguyen, Caitlin Connelly, Jonathan Powell, Fiona Harding

Journal for ImmunoTherapy of Cancer Nov 2023, 11 (Suppl 1) A1141; DOI: 10.1136/jitc-2023-SITC2023.1034
1035 CD26+ CD4+ T cells impart enhanced anti-tumor immunity and improved prognosis in early-stage breast cancer patients
Jiayi Tan, Colt Egelston, Weihua Guo, Diana Simons, Christian Avalos, Peter Lee

Journal for ImmunoTherapy of Cancer Nov 2023, 11 (Suppl 1) A1142; DOI: 10.1136/jitc-2023-SITC2023.1035
1036 Treg-specific TCR signaling as a target of cancer immunotherapy
Atsushi Tanaka, Yamin Qian, Shimon Sakaguchi

Journal for ImmunoTherapy of Cancer Nov 2023, 11 (Suppl 1) A1143; DOI: 10.1136/jitc-2023-SITC2023.1036
1037 Disruption of Aak1 kinase activity improves T cell trafficking into solid tumors by mediating CXCR3 internalization
Vianca Vianzon, Rylee Hanson, Laura Rogers

Journal for ImmunoTherapy of Cancer Nov 2023, 11 (Suppl 1) A1144; DOI: 10.1136/jitc-2023-SITC2023.1037

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