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1007 Regulatory T cells as key modulators of breast cancer brain metastasis
Isam Adam, Aaron J Longworth, Devon A Lawson

Journal for ImmunoTherapy of Cancer Nov 2023, 11 (Suppl 1) A1115; DOI: 10.1136/jitc-2023-SITC2023.1007
1008 Abstract withdrawn
Journal for ImmunoTherapy of Cancer Nov 2023, 11 (Suppl 1) A1116; DOI: 10.1136/jitc-2023-SITC2023.1008
1009 Co-stimulatory signals via CD28 and CD27 collaborate to regulate activation and IL-2 production of CD8⁺ T Cells through distinct mechanisms
Felix Behr, Anke Redeker, Suzanne Welten, Ward Vleeshouwers, Lucas Brock, Reza Nadafi, Floor van Haften, Elham Beyranvand Nejad, Juan Garcia Vallejo, Ruud van Wijdeven, Ramon Arens

Journal for ImmunoTherapy of Cancer Nov 2023, 11 (Suppl 1) A1117; DOI: 10.1136/jitc-2023-SITC2023.1009
1010 Tumor-specific CD4 T cells: the unexpected human cancer killers
Mara Cenerenti, Margaux Saillard-Salvi, Paul Gueguen, Romina Marone, Yen-Cheng Liu, Sabina Müller, Salvatore Valitutti, Hatice Altug, Daniel Speiser, Lukas Jeker, Pedro Romero, Santiago Carmona, Camilla Jandus

Journal for ImmunoTherapy of Cancer Nov 2023, 11 (Suppl 1) A1118; DOI: 10.1136/jitc-2023-SITC2023.1010
1011 The signal strength of signal 2 and 3 during T cell priming affect the functional fate of an anti-tumor T cell response
Teresa Dinter, Duncan Morgan, Vidit Bhandarkar, Lorelai Pop, Emi A Lutz, K Dane Wittrup, J Christopher Love, Stefani Spranger

Journal for ImmunoTherapy of Cancer Nov 2023, 11 (Suppl 1) A1119; DOI: 10.1136/jitc-2023-SITC2023.1011
1012 Differentiation pathways of exhausted CD8+ T cells in human breast tumors
Colt Egelston, Jiayi Tan, Weihua Guo, Peter Lee

Journal for ImmunoTherapy of Cancer Nov 2023, 11 (Suppl 1) A1120; DOI: 10.1136/jitc-2023-SITC2023.1012
1013 NKG2A expression on tumor reactive CD8 T cells is induced by IL-12
Olivier Fesneau, Wesley Rosales, Kimberly Samson, Venkatesh Rajamanickam, William Haugh, Jianguo Huang, Thomas Duhen

Journal for ImmunoTherapy of Cancer Nov 2023, 11 (Suppl 1) A1121; DOI: 10.1136/jitc-2023-SITC2023.1013
1014 Adrenergic receptors regulate T cell differentiation in viral infection and cancer
Anna-Maria Globig, Steven Zhao, Jessica Roginsky, Natalia Avina-Ochoa, Maximilian Heeg, Omkar Chaudhary, Filipe Araujo Hoffmann, Dan Chen, Carolyn O’Connor, Brinda Emu, Susan Kaech

Journal for ImmunoTherapy of Cancer Nov 2023, 11 (Suppl 1) A1122; DOI: 10.1136/jitc-2023-SITC2023.1014
1015 Tissue-specific transcriptional networks identify Hic1 as a critical regulator of intestinal Trm differentiation
Maximilian Heeg, John Crowl, Amir Ferry, Laura Biggs, John T Chang, Ananda Goldrath

Journal for ImmunoTherapy of Cancer Nov 2023, 11 (Suppl 1) A1123; DOI: 10.1136/jitc-2023-SITC2023.1015
1016 Enforcement of exhausted T cell epigenetic fate by HMG-box transcription factor TOX
Yinghui Jane Huang, Josephine R Giles, Shin Foong Ngiow, Amy E Baxter, Sasikanth Manne, Omar Khan, Simone L Park, Jennifer E Wu, E John Wherry

Journal for ImmunoTherapy of Cancer Nov 2023, 11 (Suppl 1) A1124; DOI: 10.1136/jitc-2023-SITC2023.1016

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