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924 Novel immune checkpoint interactions in Medulloblastoma and the TME
Allison M Martin, Kirsten Moziak, Natalia A Munoz Perez, Phillip M Galbo, Elodie Picarda, Robert Bell, Charles G Eberhart, Deyou Zheng, Xingxing Zang

Journal for ImmunoTherapy of Cancer Nov 2023, 11 (Suppl 1) A1027; DOI: 10.1136/jitc-2023-SITC2023.0924
925 Chemokine malfunction: CCL2-nitration mediated dysfunction of T cells in bladder cancer
Neelam Mukherjee, Niannian Ji, Zhen-Ju Shu, Zaineb Hassouneh, Robert S Svatek

Journal for ImmunoTherapy of Cancer Nov 2023, 11 (Suppl 1) A1028; DOI: 10.1136/jitc-2023-SITC2023.0925
926 BAY 2965501: a highly selective DGK zeta inhibitor for cancer immunotherapy
Rienk Offringa, Catherine Olesch, Frederik Cichon, Mareike Grees, Norbert Schmees, Ulrike Roehn, Florian Prinz, Detlef Stoeckigt, Michael Erkelenz, Thi Thanh Uyen Nguyen, Ulf Boemer, Judith Günther, Marc Kunze, Kirstin Petersen, Dennis Kirchhoff

Journal for ImmunoTherapy of Cancer Nov 2023, 11 (Suppl 1) A1029; DOI: 10.1136/jitc-2023-SITC2023.0926
927 Specific innate and adaptive immune effector subsets important for antitumor activity in HPV positive cancers
Madison OHara, Jagannadha Sastry

Journal for ImmunoTherapy of Cancer Nov 2023, 11 (Suppl 1) A1030; DOI: 10.1136/jitc-2023-SITC2023.0927
928 Generation of multi-functional and tumoricidal NKT-like antigen-specific T cells
Jaehyung Park, Jeff Bellinder, Tisha San Miguel, Neal Lawrence, Arif Azam Khan, Nathan LaVoy, Chris Tompkins, Brianna Schoen

Journal for ImmunoTherapy of Cancer Nov 2023, 11 (Suppl 1) A1031-A1032; DOI: 10.1136/jitc-2023-SITC2023.0928
929 Mutual interactions between neoantigen-specific CD8+ T cell responses facilitate immune evasion in sub-clonal tumors
Malte Roerden, Noora Harake, Byungji Kim, Yufei Cui, Forest White, Darrell Irvine, Stefani Spranger

Journal for ImmunoTherapy of Cancer Nov 2023, 11 (Suppl 1) A1033; DOI: 10.1136/jitc-2023-SITC2023.0929
930 Protein homeostasis promotes T cell stemness and enables exhausted TIL function in cancer
Nicole Scharping, Allison Cafferata, Maximilian Heeg, Maria Matias, Quynhanh Nguyen, Samuel Myers, Ananda Goldrath

Journal for ImmunoTherapy of Cancer Nov 2023, 11 (Suppl 1) A1034; DOI: 10.1136/jitc-2023-SITC2023.0930
931 Augmenting antigen presentation to improve CD8⁺ and CD4⁺ T cell responses in lung cancer
Sean-Luc Shanahan, Jason Schenkel, Tyler Jacks

Journal for ImmunoTherapy of Cancer Nov 2023, 11 (Suppl 1) A1035; DOI: 10.1136/jitc-2023-SITC2023.0931
932 Stress keratin 17 expression in head and neck cancer cells up regulates factors that are involved in M2-macrophage polarization in the tumor microenvironment
Wei Wang, Athena Golfinos, Anqi Gao, Huy Q Dinh, Paul Lambert

Journal for ImmunoTherapy of Cancer Nov 2023, 11 (Suppl 1) A1036; DOI: 10.1136/jitc-2023-SITC2023.0932
933 Heme-mediated reprogramming guides CD8⁺ T cell exhaustion in response to mitochondrial dysfunction
Yingxi Xu, Jhan-Jie Peng, Yu-Ming Chuang, Maryam Akrami, Rahul Roychoudhuri, Alfred Zippelius, Zhengtao Xiao, Ping-Chih Ho

Journal for ImmunoTherapy of Cancer Nov 2023, 11 (Suppl 1) A1037; DOI: 10.1136/jitc-2023-SITC2023.0933

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