Open access

35 Analytical characterization of a multiplex proximity extension assay panel measuring 45 cytokines in plasma from subjects with NSCLC
Anne Jang, Daniel Feingold, Mark Watson, Gwenael Pottiez, Rudolf Guilbaud, Nicholas Dupuis

Journal for ImmunoTherapy of Cancer Nov 2023, 11 (Suppl 1) A40; DOI: 10.1136/jitc-2023-SITC2023.0035
36 Degradation of type III and IV collagen associates with outcome when measured in serum from patients with metastatic melanoma treated with immune checkpoint inhibitors
Christina Jensen, Anders Kverneland, Marco Donia, Morten A Karsdal, Inge Svane, Nicholas Willumsen

Journal for ImmunoTherapy of Cancer Nov 2023, 11 (Suppl 1) A41; DOI: 10.1136/jitc-2023-SITC2023.0036
37 Collagen remodeling biomarkers in patients with locally advanced pancreatic cancer treated with stereotactic body radiotherapy plus intradermal heat-killed mycobacterium obuense (IMM-101) vaccination
Christina Jensen, Freek R van’t Land, Morten A Karsdal, Casper HJ van Eijck, Nicholas Willumsen

Journal for ImmunoTherapy of Cancer Nov 2023, 11 (Suppl 1) A42; DOI: 10.1136/jitc-2023-SITC2023.0037
38 Serum proteomics signature and its association with immune-related toxicities and survival in patients with non-small cell lung cancers (NSCLC) receiving immunotherapy
Leeseul Kim, Taegyu Um, Jeeyeon Lee, Liam Il-Young Chung, Young Kwang Chae

Journal for ImmunoTherapy of Cancer Nov 2023, 11 (Suppl 1) A43; DOI: 10.1136/jitc-2023-SITC2023.0038
39 Leveraging deep proteome profiling of plasma-derived extracellular vesicles for predictive biomarker discovery
Evelyn Ruth Lattmann, Luca Raess, Marco Tognetti, Julia Martinez Gomez, Valérie Lapaire, Roland Bruderer, Lukas Reiter, Stefanie Hiltbrunner, Alessandra Curioni-Fontecedro, Yuehan Feng, Lars M Steinmetz, Mitchell P Levesque

Journal for ImmunoTherapy of Cancer Nov 2023, 11 (Suppl 1) A44; DOI: 10.1136/jitc-2023-SITC2023.0039
40 Novel biomarker assays for detecting labyrinthin-positive adenocarcinomas for a phase I/II trial of peptide vaccine LabVax 3(22)-23 alone or in combination with pembrolizumab
Weijie Ma, Siqi Long, Dennis J Montoya, Michael Babich, Tianhong Li

Journal for ImmunoTherapy of Cancer Nov 2023, 11 (Suppl 1) A45; DOI: 10.1136/jitc-2023-SITC2023.0040
41 CD39 affect the prognostic role of NLR via N2 neutrophils in metastatic melanoma patients treated with immunotherapy
Domenico Mallardo, Mario Fordellone, Andrew White, Margaret Ottaviano, Francesca Sparano, Michael Bailey, Bianca Arianna Facchini, SuFey Ong, Piera Maiolino, Corrado Caraco, Sarah Church, Ernesta Cavalcanti, Sarah Warren, Alfredo Budillon, Alessandra Cesano, Ester Simeone, Paolo Chiodini, Paolo Ascierto

Journal for ImmunoTherapy of Cancer Nov 2023, 11 (Suppl 1) A46; DOI: 10.1136/jitc-2023-SITC2023.0041
42 IL-6 as prognostic factor in adjuvant or metastatic skin cancer patients treated with immunotherapy – a deep biomarker analysis
Domenico Mallardo, Sergio Arpino, Maria Grazia Vitale, Anita Minopoli, Marilena Tuffanelli, Claudia Trojaniello, Mario Mallardo, Grazia D’angelo, Vito Vanella, Francesca Sparano, Eleonora Cioli, Benedetta Alfano, Lucia Festino, Alfredo Budillon, Ester Simeone, Corrado Caraco, Ernesta Cavalcanti, Paolo Ascierto

Journal for ImmunoTherapy of Cancer Nov 2023, 11 (Suppl 1) A47; DOI: 10.1136/jitc-2023-SITC2023.0042
43 Harnessing the power of glycoproteomics: a cutting-edge approach for predicting treatment efficacy in metastatic melanoma with immune checkpoint inhibitors
Yana G Najjar, Chad Pickering, Paul Aiyetan, Gege Xu, Rachel Rice, Alan Mitchell, Ranjan Bhadra, Chirag Dhar, Lisa M Ebert, Michael P Brown, Gonzalo Tapia-Rico, Dennie Frederick, Xin Cong, Daniel Serie, Klaus Lindpaintner, Flavio Schwarz, Genevieve M Boland, Joseph Markowitz

Journal for ImmunoTherapy of Cancer Nov 2023, 11 (Suppl 1) A48-A50; DOI: 10.1136/jitc-2023-SITC2023.0043
5 Severely immunodeficient NOG-EXL mice allow for humanization and development of a human glioblastoma-derived tumor microenvironment
Zev Binder, Lamia Lamrani, Anthony Secreto, Nicholas Skuli, Moriah Jacobson, Charles-Antoine Assenmacher, Elinor Willis, Enrico Radaelli, Donald O’Rourke, Cecile Alanio, Maclean Nasrallah

Journal for ImmunoTherapy of Cancer Nov 2023, 11 (Suppl 1) A5; DOI: 10.1136/jitc-2023-SITC2023.0005

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