Open access

87 Monitoring in vivo CD8 T and tumor cell metabolic changes in solid tumors during an in situ vaccine using autofluorescence imaging
Alexa R Heaton, Anna Hoefges, Nathaniel J Burkard, Arika S Feils, Noah W Tsarovsky, Garrett M Lublin, Alina A Hampton, Amy K Erbe-Gurel, Alexander L Rakhmilevich, Paul M Sondel, Melissa C Skala

Journal for ImmunoTherapy of Cancer Nov 2023, 11 (Suppl 1) A100; DOI: 10.1136/jitc-2023-SITC2023.0087
88 Rapid and efficient removal of hematoxylin & eosin (H&E) staining for fluorescence-based multiplex tissue analysis
Kevin Hwang, Grace Vezeau, Edyta Krzymanska-Olejnik, Alexander Veith, Gourab Chatterjee, Je H Lee

Journal for ImmunoTherapy of Cancer Nov 2023, 11 (Suppl 1) A101; DOI: 10.1136/jitc-2023-SITC2023.0088
89 Non-invasive imaging of tumor-infiltrating B lymphocytes in a triple negative breast cancer model using anti-CD20 immunoPET
Sunidhi Jaiswal, Saad N Ahmed, Felix B Salazar, Masoud Farshbaf, Bao Y Chen, Jennifer Chean, Kirstin A Zettlitz

Journal for ImmunoTherapy of Cancer Nov 2023, 11 (Suppl 1) A102; DOI: 10.1136/jitc-2023-SITC2023.0089
11 Humanized ICOS mice as a novel tool for predicting and monitoring T-cell-mediated immunotherapy response
Ruili Lv, Zan Zhang, Jing Guo, Chong Li, Ravneet Chhabra, Yuelei Shen

Journal for ImmunoTherapy of Cancer Nov 2023, 11 (Suppl 1) A11; DOI: 10.1136/jitc-2023-SITC2023.0011
12 Humanized CD200/CD200R mice as a tool for evaluating novel therapeutics
Ruili Lv, Chong Li, Zhiyuan Shen, Qiurong Wang, Yuelei Shen

Journal for ImmunoTherapy of Cancer Nov 2023, 11 (Suppl 1) A12; DOI: 10.1136/jitc-2023-SITC2023.0012
13 Development of a preclinical CD98HC mouse model for therapeutic studies
Ruili Lv, Zhiyuan Shen, Chong Li, Natalie Marchi, Yuelei Shen

Journal for ImmunoTherapy of Cancer Nov 2023, 11 (Suppl 1) A13; DOI: 10.1136/jitc-2023-SITC2023.0013
14 Humanized TFR1/CD71 knockin mouse model enables in vivo assessment of TFR1-targeted antibody therapies for cancer and beyond to across the blood-brain barrier
Hechun Ma, Yi Li, Ping Yang, Renxing Zhang, Dongxiao Feng, Jian Fei, Ruilin Sun, Daniel X He

Journal for ImmunoTherapy of Cancer Nov 2023, 11 (Suppl 1) A14; DOI: 10.1136/jitc-2023-SITC2023.0014
15 Pulsed electric field therapy increases immune response and improves murine 4T1 breast tumor local and metastatic outcomes relative to radiofrequency ablation
Ebtesam Nafie, Chiara Pastori, Mukta Wagh, Ella Goldschmidt, Robert Neal

Journal for ImmunoTherapy of Cancer Nov 2023, 11 (Suppl 1) A15-A17; DOI: 10.1136/jitc-2023-SITC2023.0015
16 A novel B2m-deficient immunodeficient model expressing human IL15 for preclinical evaluation of T cell and NK cell-based therapies
Yanhui Nie, Xiaofei Zhou, Sujata Nerle, Qiang Liu, Jiangfeng Yuan, Yuelei Shen

Journal for ImmunoTherapy of Cancer Nov 2023, 11 (Suppl 1) A18; DOI: 10.1136/jitc-2023-SITC2023.0016
17 Humanized NKP46 mouse models for testing novel NK cell-based immunotherapies
Zhenlan Niu, Xiaofei Zhou, Yongshun Li, James Jin, Yuelei Shen

Journal for ImmunoTherapy of Cancer Nov 2023, 11 (Suppl 1) A19; DOI: 10.1136/jitc-2023-SITC2023.0017

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