Open access

201 Discovering next-generation biomarkers through integrating single-cell ‘omics and artificial intelligence
Corinne Solier, Sarah Carl

Journal for ImmunoTherapy of Cancer Nov 2023, 11 (Suppl 1) A229; DOI: 10.1136/jitc-2023-SITC2023.0201
202 Spatial analysis of tumor-infiltrating lymphocytes in tumor microenvironment in non-small cell lung cancer patients who have resistance after EGFR tyrosine kinase inhibitors
Yeong Hak Bang, Chang Ho Ahn, CheolYong Joe, Sehhoon Park, Hyun Ae Jung, Yoon-La Choi, Jin Seok Ahn, Myung Ju Ahn, Seunghwan Shin, Chan-Young Ock, Se-Hoon Lee

Journal for ImmunoTherapy of Cancer Nov 2023, 11 (Suppl 1) A230; DOI: 10.1136/jitc-2023-SITC2023.0202
203 Spatial whole transcriptome analysis of differential expression for biomarker discovery in colorectal cancer
Elim Cheung, Baowen Zhang, Vidyodhaya Sundaram, Lutong Zhang, Tong Lu

Journal for ImmunoTherapy of Cancer Nov 2023, 11 (Suppl 1) A231; DOI: 10.1136/jitc-2023-SITC2023.0203
204 Unveiling differential gene expression profiling and potential biomarker in breast cancer with the NanoString GeoMx digital spatial profiler
Elim Cheung, Baowen Zhang, Jinghao Tian, Tong Lu, Vidyodhaya Sundaram

Journal for ImmunoTherapy of Cancer Nov 2023, 11 (Suppl 1) A232; DOI: 10.1136/jitc-2023-SITC2023.0204
205 AI driven interrogation of spatial proteomic and transcriptomics atlases in the tumor microenvironment of triple negative breast cancer
Sarah Church, Kyla Teplitz, Ben Sutton, Megan Vandenberg, Alyssa Rosenbloom, Christine Kang, Regan Baird, Jenifer Caldara, James Mansfield

Journal for ImmunoTherapy of Cancer Nov 2023, 11 (Suppl 1) A233; DOI: 10.1136/jitc-2023-SITC2023.0205
206 Validation of NanoString® technologies for solid tumor clinical studies: robustness, precision and inter-site comparison
Alexy Promonet, Ali-Réza Stroili, Xavier Pichon, Amanda Finan-Marchi

Journal for ImmunoTherapy of Cancer Nov 2023, 11 (Suppl 1) A234; DOI: 10.1136/jitc-2023-SITC2023.0206
207 The spatially-resolved proteomic atlas of the tumor immune architecture of HER2-positive breast cancer and response to neoadjuvant anti-HER2 therapy-based chemotherapy
Saranya Chumsri, Jennifer Kachergus, Ji Shi, Yi Liu, Yaohua Ma, Alyssa Rosenbloom, Shilah Bonnett, Mark Conner, Erin Piazza, Brian Filanoski, Rhonda Meredith, Christine Kang, Lesley Isgur, Margaret Hoang, Gary Geiss, Joseph Beechem, EA Thompson

Journal for ImmunoTherapy of Cancer Nov 2023, 11 (Suppl 1) A235; DOI: 10.1136/jitc-2023-SITC2023.0207
208 Investigating the E-Cadherin/β-catenin interaction in colon cancer: a proximity ligation approach
Hampus Elofsson, Agata Zieba-Wicher

Journal for ImmunoTherapy of Cancer Nov 2023, 11 (Suppl 1) A236; DOI: 10.1136/jitc-2023-SITC2023.0208
209 Fully automated in situ detection of protein-protein interactions in tissue
Hampus Elofsson, Linda Arngården, Olof Hahne, Daniel Ekman, Lena Beckman, Agata Zieba-Wicher

Journal for ImmunoTherapy of Cancer Nov 2023, 11 (Suppl 1) A237; DOI: 10.1136/jitc-2023-SITC2023.0209
210 New approaches to understanding the tumor microenvironment: in situ detection of immune checkpoint interactions in cancer patient tissue samples
Jonas Vennberg, Desirée Edén, Sara Bodbin, Ka IAu Ieong, Lena Beckman, Daniel Ekman, Agata Zieba-Wicher

Journal for ImmunoTherapy of Cancer Nov 2023, 11 (Suppl 1) A238; DOI: 10.1136/jitc-2023-SITC2023.0210

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