- Diffusion-Weighted Imaging Reveals Impaired Glymphatic Clearance in Idiopathic Intracranial Hypertension
The diffusivity along the cerebral perivascular spaces (DTI-ALPS technique) and lateral association and projection fibers in patients with IIH were compared with normal controls. Using the degree of diffusivity as a surrogate for glymphatic function, IIH patients were shown to have a significantly lower glymphatic clearance compared with controls (P=.005), with a significant association between declining glymphatic clearance and increasing Frisen papilledema grade (P=.046).
- Specificity of Quantitative Functional Brain Mapping with Arterial Spin-Labeling for Preoperative Assessment
This study assessed the performance of ASL compared with BOLD imaging for localization specificity of functional cortex during motor and somatosensory tasks in a cohort of healthy subjects, using TMS hand somatotopy depicted as the ground truth.
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