- MR Imaging of IgG4-Related Disease in the Head and Neck and Brain
Autoimmune pancreatitis, sclerosing cholangitis and sialoadenitis, retroperitoneal and mediastinal fibrosis, and insterstitial pneumonia are all IgG-4 related disorders. This short article discusses the head and neck manifestations of this disease: orbital pseudotumor and lacrimal gland, cranial nerve, and pituitary involvement. Intracranially, the dura may be also affected. All of these lesions were contrast-enhancing and T2 dark, findings to be kept in mind so that one can suggest their etiology.
- Retinoblastoma: Value of Dynamic Contrast-Enhanced MR Imaging and Correlation with Tumor Angiogenesis
Fifteen patients with retinoblastoma were assessed with dynamic contrast-enhanced MRI over a period of 8 minutes; late contrast enhancement was also studied. The authors found that during the early phase of the perfusion studies the time curve correlated with microvessel density whereas late enhancement correlated with tumor necrosis. Thus, dynamic contrast-enhanced MRI may be used to assess angiogenesis and necrosis and may be used to monitor treatment.
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