- Endovascular Cerebral Venous Sinus Imaging with Optical Coherence Tomography
Endovascular optical coherence tomography imaging was feasible in this preclinical animal study. Adoption of this imaging technique in the human cerebral venous sinus could aid in the diagnosis, treatment, and understanding of the pathophysiology of various diseases of the sinus.
- Treatment of Ruptured Blister-Like Aneurysms with the FRED Flow Diverter: A Multicenter Experience
In a retrospective multicenter study, all patients treated with the FRED for a ruptured intracranial blister-like aneurysm between January 2013 and May 2019 were analyzed. In total, 30 patients with 30 ruptured blister-like aneurysms were treated. Immediate complete aneurysm obliteration with the FRED was achieved in 10 patients (33%). Of the 26 patients with follow-up, complete obliteration was achieved in 21 patients (80%) after 6 months and in 24 patients (92%) in the final follow-up (median, 22 months). The authors conclude that treatment of ruptured blister-like aneurysms with the FRED is safe and effective.
- Characteristics of Large-Vessel Occlusion Associated with COVID-19 and Ischemic Stroke
Consecutive ischemic stroke and TIA admissions (COVID and non-COVID) to the authors' hospital during a 10-week period from March 1 to May 10, 2020 were collected and compared with data from the same time period in 2019. Among 20 patients with COVID-19 and acute ischemic stroke, 15 (75%) had large-vessel occlusion. These patients were young (mean age, 46.5 years), male (93%), without major burden of traditional cardiovascular risk factors, and had a severe stroke presentation. Large vessel occlusions were observed in multiple vessels (40%), uncommonly affected vessels, and atypical locations with a large thrombus burden.
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