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Research ArticleNEUROINTERVENTION

Proximal Protection Devices for Carotid Artery Stent Placement: A Benchtop Assessment of Flow Reversal Performance

Jiahui Li, Esref Alperen Bayraktar, Cem Bilgin, Yang Liu, Yigit Can Senol, Jonathan Cortese, Ramanathan Kadirvel, Waleed Brinjikji and David F. Kallmes
American Journal of Neuroradiology July 2025, DOI: https://doi.org/10.3174/ajnr.A8664
Jiahui Li
aFrom the Department of Radiology (J.L., E.A.B., C.B., J.C., R.K., W.B., D.F.K.), Mayo Clinic Rochester, Rochester, Minnesota
bStroke Research (J.L.), Vall d’Hebron Research Institute, Barcelona, Spain
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Esref Alperen Bayraktar
aFrom the Department of Radiology (J.L., E.A.B., C.B., J.C., R.K., W.B., D.F.K.), Mayo Clinic Rochester, Rochester, Minnesota
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  • ORCID record for Esref Alperen Bayraktar
Cem Bilgin
aFrom the Department of Radiology (J.L., E.A.B., C.B., J.C., R.K., W.B., D.F.K.), Mayo Clinic Rochester, Rochester, Minnesota
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Yang Liu
cGlobal Institute of Future Technology (Y.L.), Shanghai Jiao Tong University, Shanghai, China
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Yigit Can Senol
dDepartment of Neurologic Surgery (Y.C.S., R.K., W.B.), Mayo Clinic Rochester, Rochester, Minnesota
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Jonathan Cortese
aFrom the Department of Radiology (J.L., E.A.B., C.B., J.C., R.K., W.B., D.F.K.), Mayo Clinic Rochester, Rochester, Minnesota
eDepartment of Neurointerventional Radiology (NEURI Vascular Center) (J.C.), Bicetre University Hospital, Le Kremlin Bicetre, France
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Ramanathan Kadirvel
aFrom the Department of Radiology (J.L., E.A.B., C.B., J.C., R.K., W.B., D.F.K.), Mayo Clinic Rochester, Rochester, Minnesota
dDepartment of Neurologic Surgery (Y.C.S., R.K., W.B.), Mayo Clinic Rochester, Rochester, Minnesota
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Waleed Brinjikji
aFrom the Department of Radiology (J.L., E.A.B., C.B., J.C., R.K., W.B., D.F.K.), Mayo Clinic Rochester, Rochester, Minnesota
dDepartment of Neurologic Surgery (Y.C.S., R.K., W.B.), Mayo Clinic Rochester, Rochester, Minnesota
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David F. Kallmes
aFrom the Department of Radiology (J.L., E.A.B., C.B., J.C., R.K., W.B., D.F.K.), Mayo Clinic Rochester, Rochester, Minnesota
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References

  1. 1.↵
    1. Texakalidis P,
    2. Letsos A,
    3. Kokkinidis DG, et al
    . Proximal embolic protection versus distal filter protection versus combined protection in carotid artery stenting: a systematic review and meta-analysis. Cardiovasc Revasc Med 2018;19:545–52 doi:10.1016/j.carrev.2017.12.010 pmid:29502959
    CrossRefPubMed
  2. 2.↵
    1. Kim MS,
    2. Rho MH,
    3. Hong HP, et al
    . Comparison of embolic protection with proximal and distal protection devices: periprocedural complications, clinical outcomes, and cerebral embolic lesions on diffusion-weighted magnetic resonance imaging. World Neurosurg 2020;135:e731–37 doi:10.1016/j.wneu.2019.12.121 pmid:31899400
    CrossRefPubMed
  3. 3.↵
    1. Liang P,
    2. Soden P,
    3. Wyers MC, et al
    . The role of transfemoral carotid artery stenting with proximal balloon occlusion embolic protection in the contemporary endovascular management of carotid artery stenosis. J Vasc Surg 2020;72:1701–10 doi:10.1016/j.jvs.2020.02.036 pmid:32251772
    CrossRefPubMed
  4. 4.↵
    1. Kashyap VS,
    2. Schneider PA,
    3. Foteh M, et al
    ; ROADSTER 2 Investigators. Early outcomes in the ROADSTER 2 study of transcarotid artery revascularization in patients with significant carotid artery disease. Stroke 2020;51:2620–29 doi:10.1161/STROKEAHA.120.030550 pmid:32811386
    CrossRefPubMed
  5. 5.↵
    1. Wu WW,
    2. Liang P,
    3. O’Donnell TFX, et al
    . Anatomic eligibility for transcarotid artery revascularization and transfemoral carotid artery stenting. J Vasc Surg 2019;69:1452–60 doi:10.1016/j.jvs.2018.11.051 pmid:30853384
    CrossRefPubMed
  6. 6.↵
    1. Wang J,
    2. Zheng C,
    3. Hou B, et al
    . Four collateral circulation pathways were observed after common carotid artery occlusion. BMC Neurol 2019;19:201 doi:10.1186/s12883-019-1425-0 pmid:31429719
    CrossRefPubMed
  7. 7.↵
    1. Ansel GM,
    2. Hopkins LN,
    3. Jaff MR, et al
    ; Investigators for the ARMOUR Pivotal Trial. Safety and effectiveness of the INVATEC MO.MA® proximal cerebral protection device during carotid artery stenting: results from the ARMOUR pivotal trial. Catheter Cardiovasc Interv 2010;76:1–8 doi:10.1002/ccd.22439 pmid:20222019
    CrossRefPubMed
  8. 8.↵
    1. Bilgin C,
    2. Hutar J,
    3. Li J, et al
    . Catheter design primer for neurointerventionalists. J Neurointerv Surg 2023;15:1117–21 doi:10.1136/jnis-2022-019567 pmid:36597952
    Abstract/FREE Full Text
  9. 9.↵
    1. Cuoco JA,
    2. Entwistle JJ,
    3. Siddiq F, et al
    . The balloon occlusion sheath for stroke (BOSS) balloon guide catheter for stroke intervention: safety and technical success. Interv Neuroradiol 2023 Aug 30. [Epub ahead of print] doi:10.1177/15910199231198273 pmid:37649344
    CrossRefPubMed
  10. 10.↵
    1. Meschia JF,
    2. Bushnell C,
    3. Boden-Albala B
    ; Council on Hypertension, et al. Guidelines for the primary prevention of stroke. Stroke 2014;45:3754–832 doi:10.1161/STR.0000000000000046 pmid:25355838
    Abstract/FREE Full Text
  11. 11.↵
    1. Kim HW,
    2. Regenhardt RW,
    3. D’Amato SA, et al
    . Asymptomatic carotid artery stenosis: a summary of current state of evidence for revascularization and emerging high-risk features. J Neurointerv Surg 2023;15:717–22 doi:10.1136/jnis-2022-018732 pmid:36190935
    Abstract/FREE Full Text
  12. 12.↵
    1. Perrira N,
    2. Shuib AS,
    3. Phang SW, et al
    . Experimental investigation of blood mimicking fluid viscosity for application in 3D-Printed medical simulator. J Phys Conf Ser 2022;2222:012016 doi:10.1088/1742-6596/2222/1/012016
    CrossRef
  13. 13.↵
    1. Zarrinkoob L,
    2. Ambarki K,
    3. Wåhlin A, et al
    . Blood flow distribution in cerebral arteries. J Cereb Blood Flow Metab 2015;35:648–54 doi:10.1038/jcbfm.2014.241 pmid:25564234
    CrossRefPubMed
  14. 14.↵
    1. Aleksic M,
    2. Brunkwall J
    . Extracranial blood flow distribution during carotid surgery. Eur J Vasc Endovasc Surg 2009;38:552–55 doi:10.1016/j.ejvs.2009.06.023 pmid:19679497
    CrossRefPubMed
  15. 15.↵
    1. Clair DG,
    2. Hopkins LN,
    3. Mehta M, et al
    ; EMPiRE Clinical Study Investigators. Neuroprotection during carotid artery stenting using the GORE flow reversal system: 30-day outcomes in the EMPiRE Clinical Study. Catheter Cardiovasc Interv 2011;77:420–29 doi:10.1002/ccd.22789 pmid:20853365
    CrossRefPubMedWeb of Science
  16. 16.↵
    1. Parodi J,
    2. Bates MC,
    3. Ohki T, et al
    . The history of proximal carotid protection and flow reversal to prevent stent angioplasty embolization. Semin Vasc Surg 2018;31:9–14 doi:10.1053/j.semvascsurg.2018.03.002 pmid:29891030
    CrossRefPubMed
  17. 17.↵
    1. Salem MM,
    2. Kvint S,
    3. Baig AA, et al
    . Carotid artery revascularization using the Walrus balloon guide catheter: safety and feasibility from a US multicenter experience. J Neurointerv Surg 2022;14:709–17 doi:10.1136/neurintsurg-2021-018126 pmid:34686574
    Abstract/FREE Full Text
  18. 18.↵
    1. Gabrielli R,
    2. Castrucci T,
    3. Siani A, et al
    . Common carotid artery endovascular clamping for neuroprotection during carotid stenting: flow-gate system as an innovative treatment approach. Catheter Cardiovasc Interv 2021;97:E71–78 doi:10.1002/ccd.29287 pmid:32985787
    CrossRefPubMed
  19. 19.↵
    1. Kashyap VS,
    2. So KL,
    3. Schneider PA, et al
    . One-year outcomes after transcarotid artery revascularization (TCAR) in the ROADSTER 2 trial. J Vasc Surg 2022;76:466–73 doi:10.1016/j.jvs.2022.03.872 pmid:35381327
    CrossRefPubMed
  20. 20.↵
    1. Castro-Afonso LH de,
    2. Abud LG,
    3. Rolo JG, et al
    . Flow reversal versus filter protection: a pilot carotid artery stenting randomized trial. Circ Cardiovasc Interv 2013;6:552–59 doi:10.1161/CIRCINTERVENTIONS.113.000479 pmid:24084627
    Abstract/FREE Full Text
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Cite this article
Jiahui Li, Esref Alperen Bayraktar, Cem Bilgin, Yang Liu, Yigit Can Senol, Jonathan Cortese, Ramanathan Kadirvel, Waleed Brinjikji, David F. Kallmes
Proximal Protection Devices for Carotid Artery Stent Placement: A Benchtop Assessment of Flow Reversal Performance
American Journal of Neuroradiology Jul 2025, DOI: 10.3174/ajnr.A8664

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Proximal Protection Devices for Carotid Stenting
Jiahui Li, Esref Alperen Bayraktar, Cem Bilgin, Yang Liu, Yigit Can Senol, Jonathan Cortese, Ramanathan Kadirvel, Waleed Brinjikji, David F. Kallmes
American Journal of Neuroradiology Jul 2025, DOI: 10.3174/ajnr.A8664
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