Research ArticleORIGINAL RESEARCH
Automated Detection of Black Hole Sign for Intracerebral Hemorrhage Patients Using Self-Supervised Learning
Hanyin Wang, Tim Schwirtlich, Ethan J. Houskamp, Meghan R. Hutch, Julianne X. Murphy, Juliana S. do Nascimento, Andrea Zini, Laura Brancaleoni, Sebastiano Giacomozzi, Yuan Luo and Andrew M. Naidech
American Journal of Neuroradiology May 2025, ajnr.A8826; DOI: https://doi.org/10.3174/ajnr.A8826
Hanyin Wang
From the Department of Preventive Medicine (H.W., T.S., M.R.H, J.X.M, J.S.N, Y.L.), Department of Neurological Surgery (E.J.H.), and Department of Neurology (A.M.N.), Northwestern University Feinberg School of Medicine, Chicago, Illinois, USA; IRCCS Istituto delle Scienze Neurologiche di Bologna, Department of Neurology and Stroke Center (A.Z., L.B.), Maggiore Hospital, Bologna, Italy; Department of Biomedical and Neuromotor Sciences (DIBINEM) (S.G.), Alma Mater Studiorum-University of Bologna, Bologna, Italy.
Tim Schwirtlich
From the Department of Preventive Medicine (H.W., T.S., M.R.H, J.X.M, J.S.N, Y.L.), Department of Neurological Surgery (E.J.H.), and Department of Neurology (A.M.N.), Northwestern University Feinberg School of Medicine, Chicago, Illinois, USA; IRCCS Istituto delle Scienze Neurologiche di Bologna, Department of Neurology and Stroke Center (A.Z., L.B.), Maggiore Hospital, Bologna, Italy; Department of Biomedical and Neuromotor Sciences (DIBINEM) (S.G.), Alma Mater Studiorum-University of Bologna, Bologna, Italy.
Ethan J. Houskamp
From the Department of Preventive Medicine (H.W., T.S., M.R.H, J.X.M, J.S.N, Y.L.), Department of Neurological Surgery (E.J.H.), and Department of Neurology (A.M.N.), Northwestern University Feinberg School of Medicine, Chicago, Illinois, USA; IRCCS Istituto delle Scienze Neurologiche di Bologna, Department of Neurology and Stroke Center (A.Z., L.B.), Maggiore Hospital, Bologna, Italy; Department of Biomedical and Neuromotor Sciences (DIBINEM) (S.G.), Alma Mater Studiorum-University of Bologna, Bologna, Italy.
Meghan R. Hutch
From the Department of Preventive Medicine (H.W., T.S., M.R.H, J.X.M, J.S.N, Y.L.), Department of Neurological Surgery (E.J.H.), and Department of Neurology (A.M.N.), Northwestern University Feinberg School of Medicine, Chicago, Illinois, USA; IRCCS Istituto delle Scienze Neurologiche di Bologna, Department of Neurology and Stroke Center (A.Z., L.B.), Maggiore Hospital, Bologna, Italy; Department of Biomedical and Neuromotor Sciences (DIBINEM) (S.G.), Alma Mater Studiorum-University of Bologna, Bologna, Italy.
Julianne X. Murphy
From the Department of Preventive Medicine (H.W., T.S., M.R.H, J.X.M, J.S.N, Y.L.), Department of Neurological Surgery (E.J.H.), and Department of Neurology (A.M.N.), Northwestern University Feinberg School of Medicine, Chicago, Illinois, USA; IRCCS Istituto delle Scienze Neurologiche di Bologna, Department of Neurology and Stroke Center (A.Z., L.B.), Maggiore Hospital, Bologna, Italy; Department of Biomedical and Neuromotor Sciences (DIBINEM) (S.G.), Alma Mater Studiorum-University of Bologna, Bologna, Italy.
Juliana S. do Nascimento
From the Department of Preventive Medicine (H.W., T.S., M.R.H, J.X.M, J.S.N, Y.L.), Department of Neurological Surgery (E.J.H.), and Department of Neurology (A.M.N.), Northwestern University Feinberg School of Medicine, Chicago, Illinois, USA; IRCCS Istituto delle Scienze Neurologiche di Bologna, Department of Neurology and Stroke Center (A.Z., L.B.), Maggiore Hospital, Bologna, Italy; Department of Biomedical and Neuromotor Sciences (DIBINEM) (S.G.), Alma Mater Studiorum-University of Bologna, Bologna, Italy.
Andrea Zini
From the Department of Preventive Medicine (H.W., T.S., M.R.H, J.X.M, J.S.N, Y.L.), Department of Neurological Surgery (E.J.H.), and Department of Neurology (A.M.N.), Northwestern University Feinberg School of Medicine, Chicago, Illinois, USA; IRCCS Istituto delle Scienze Neurologiche di Bologna, Department of Neurology and Stroke Center (A.Z., L.B.), Maggiore Hospital, Bologna, Italy; Department of Biomedical and Neuromotor Sciences (DIBINEM) (S.G.), Alma Mater Studiorum-University of Bologna, Bologna, Italy.
Laura Brancaleoni
From the Department of Preventive Medicine (H.W., T.S., M.R.H, J.X.M, J.S.N, Y.L.), Department of Neurological Surgery (E.J.H.), and Department of Neurology (A.M.N.), Northwestern University Feinberg School of Medicine, Chicago, Illinois, USA; IRCCS Istituto delle Scienze Neurologiche di Bologna, Department of Neurology and Stroke Center (A.Z., L.B.), Maggiore Hospital, Bologna, Italy; Department of Biomedical and Neuromotor Sciences (DIBINEM) (S.G.), Alma Mater Studiorum-University of Bologna, Bologna, Italy.
Sebastiano Giacomozzi
From the Department of Preventive Medicine (H.W., T.S., M.R.H, J.X.M, J.S.N, Y.L.), Department of Neurological Surgery (E.J.H.), and Department of Neurology (A.M.N.), Northwestern University Feinberg School of Medicine, Chicago, Illinois, USA; IRCCS Istituto delle Scienze Neurologiche di Bologna, Department of Neurology and Stroke Center (A.Z., L.B.), Maggiore Hospital, Bologna, Italy; Department of Biomedical and Neuromotor Sciences (DIBINEM) (S.G.), Alma Mater Studiorum-University of Bologna, Bologna, Italy.
Yuan Luo
From the Department of Preventive Medicine (H.W., T.S., M.R.H, J.X.M, J.S.N, Y.L.), Department of Neurological Surgery (E.J.H.), and Department of Neurology (A.M.N.), Northwestern University Feinberg School of Medicine, Chicago, Illinois, USA; IRCCS Istituto delle Scienze Neurologiche di Bologna, Department of Neurology and Stroke Center (A.Z., L.B.), Maggiore Hospital, Bologna, Italy; Department of Biomedical and Neuromotor Sciences (DIBINEM) (S.G.), Alma Mater Studiorum-University of Bologna, Bologna, Italy.
Andrew M. Naidech
From the Department of Preventive Medicine (H.W., T.S., M.R.H, J.X.M, J.S.N, Y.L.), Department of Neurological Surgery (E.J.H.), and Department of Neurology (A.M.N.), Northwestern University Feinberg School of Medicine, Chicago, Illinois, USA; IRCCS Istituto delle Scienze Neurologiche di Bologna, Department of Neurology and Stroke Center (A.Z., L.B.), Maggiore Hospital, Bologna, Italy; Department of Biomedical and Neuromotor Sciences (DIBINEM) (S.G.), Alma Mater Studiorum-University of Bologna, Bologna, Italy.

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Accepted Manuscript
Hanyin Wang, Tim Schwirtlich, Ethan J. Houskamp, Meghan R. Hutch, Julianne X. Murphy, Juliana S. do Nascimento, Andrea Zini, Laura Brancaleoni, Sebastiano Giacomozzi, Yuan Luo, Andrew M. Naidech
Automated Detection of Black Hole Sign for Intracerebral Hemorrhage Patients Using Self-Supervised Learning
American Journal of Neuroradiology May 2025, ajnr.A8826; DOI: 10.3174/ajnr.A8826
Accepted Manuscript
Automated Detection of Black Hole Sign for Intracerebral Hemorrhage Patients Using Self-Supervised Learning
Hanyin Wang, Tim Schwirtlich, Ethan J. Houskamp, Meghan R. Hutch, Julianne X. Murphy, Juliana S. do Nascimento, Andrea Zini, Laura Brancaleoni, Sebastiano Giacomozzi, Yuan Luo, Andrew M. Naidech
American Journal of Neuroradiology May 2025, ajnr.A8826; DOI: 10.3174/ajnr.A8826
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