Research ArticleORIGINAL RESEARCH
Three-Dimensional Quantified Morphological Predictors of Intracranial Aneurysm Instability: A Longitudinal Study
Maarten J. Kamphuis, Laura T. van der Kamp, Ruben P.A. van Eijk, Kimberley M. Timmins, Gabriel J.E. Rinkel, Jeroen Hendrikse, Mervyn D.I. Vergouwen and Irene C. van der Schaaf
American Journal of Neuroradiology April 2025, ajnr.A8809; DOI: https://doi.org/10.3174/ajnr.A8809
Maarten J. Kamphuis
From the Department of Radiology (M.J.K., J.H., I.C.v.d.S.), Department of Neurology and Neurosurgery, UMC Utrecht Brain Center (M.J.K., L.T.v.d.K., R.P.A.v.E., M.D.I.V., G.J.E.R.), Biostatistics & Research Support, Julius Center for Health Sciences and Primary Care (R.P.A.v.E), and the Image Sciences Institute (K.M.T.), University Medical Center Utrecht, Utrecht University, Utrecht, The Netherlands.
Laura T. van der Kamp
From the Department of Radiology (M.J.K., J.H., I.C.v.d.S.), Department of Neurology and Neurosurgery, UMC Utrecht Brain Center (M.J.K., L.T.v.d.K., R.P.A.v.E., M.D.I.V., G.J.E.R.), Biostatistics & Research Support, Julius Center for Health Sciences and Primary Care (R.P.A.v.E), and the Image Sciences Institute (K.M.T.), University Medical Center Utrecht, Utrecht University, Utrecht, The Netherlands.
Ruben P.A. van Eijk
From the Department of Radiology (M.J.K., J.H., I.C.v.d.S.), Department of Neurology and Neurosurgery, UMC Utrecht Brain Center (M.J.K., L.T.v.d.K., R.P.A.v.E., M.D.I.V., G.J.E.R.), Biostatistics & Research Support, Julius Center for Health Sciences and Primary Care (R.P.A.v.E), and the Image Sciences Institute (K.M.T.), University Medical Center Utrecht, Utrecht University, Utrecht, The Netherlands.
Kimberley M. Timmins
From the Department of Radiology (M.J.K., J.H., I.C.v.d.S.), Department of Neurology and Neurosurgery, UMC Utrecht Brain Center (M.J.K., L.T.v.d.K., R.P.A.v.E., M.D.I.V., G.J.E.R.), Biostatistics & Research Support, Julius Center for Health Sciences and Primary Care (R.P.A.v.E), and the Image Sciences Institute (K.M.T.), University Medical Center Utrecht, Utrecht University, Utrecht, The Netherlands.
Gabriel J.E. Rinkel
From the Department of Radiology (M.J.K., J.H., I.C.v.d.S.), Department of Neurology and Neurosurgery, UMC Utrecht Brain Center (M.J.K., L.T.v.d.K., R.P.A.v.E., M.D.I.V., G.J.E.R.), Biostatistics & Research Support, Julius Center for Health Sciences and Primary Care (R.P.A.v.E), and the Image Sciences Institute (K.M.T.), University Medical Center Utrecht, Utrecht University, Utrecht, The Netherlands.
Jeroen Hendrikse
From the Department of Radiology (M.J.K., J.H., I.C.v.d.S.), Department of Neurology and Neurosurgery, UMC Utrecht Brain Center (M.J.K., L.T.v.d.K., R.P.A.v.E., M.D.I.V., G.J.E.R.), Biostatistics & Research Support, Julius Center for Health Sciences and Primary Care (R.P.A.v.E), and the Image Sciences Institute (K.M.T.), University Medical Center Utrecht, Utrecht University, Utrecht, The Netherlands.
Mervyn D.I. Vergouwen
From the Department of Radiology (M.J.K., J.H., I.C.v.d.S.), Department of Neurology and Neurosurgery, UMC Utrecht Brain Center (M.J.K., L.T.v.d.K., R.P.A.v.E., M.D.I.V., G.J.E.R.), Biostatistics & Research Support, Julius Center for Health Sciences and Primary Care (R.P.A.v.E), and the Image Sciences Institute (K.M.T.), University Medical Center Utrecht, Utrecht University, Utrecht, The Netherlands.
Irene C. van der Schaaf
From the Department of Radiology (M.J.K., J.H., I.C.v.d.S.), Department of Neurology and Neurosurgery, UMC Utrecht Brain Center (M.J.K., L.T.v.d.K., R.P.A.v.E., M.D.I.V., G.J.E.R.), Biostatistics & Research Support, Julius Center for Health Sciences and Primary Care (R.P.A.v.E), and the Image Sciences Institute (K.M.T.), University Medical Center Utrecht, Utrecht University, Utrecht, The Netherlands.

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Accepted Manuscript
Maarten J. Kamphuis, Laura T. van der Kamp, Ruben P.A. van Eijk, Kimberley M. Timmins, Gabriel J.E. Rinkel, Jeroen Hendrikse, Mervyn D.I. Vergouwen, Irene C. van der Schaaf
Three-Dimensional Quantified Morphological Predictors of Intracranial Aneurysm Instability: A Longitudinal Study
American Journal of Neuroradiology Apr 2025, ajnr.A8809; DOI: 10.3174/ajnr.A8809
Accepted Manuscript
Three-Dimensional Quantified Morphological Predictors of Intracranial Aneurysm Instability: A Longitudinal Study
Maarten J. Kamphuis, Laura T. van der Kamp, Ruben P.A. van Eijk, Kimberley M. Timmins, Gabriel J.E. Rinkel, Jeroen Hendrikse, Mervyn D.I. Vergouwen, Irene C. van der Schaaf
American Journal of Neuroradiology Apr 2025, ajnr.A8809; DOI: 10.3174/ajnr.A8809
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