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Review ArticleReview articles

Clinical Translation of Hyperpolarized 13C Metabolic Probes for Glioma Imaging

Adam W. Autry, Yaewon Kim, Duy Dang, Hsin-Yu Chen, James B. Slater, Robert A. Bok, Duan Xu, Janine M. Lupo, Jeremy W. Gordon, Peder E.Z. Larson, Daniel B. Vigneron, Yan Li and Susan M. Chang
American Journal of Neuroradiology March 2025, ajnr.A8726; DOI: https://doi.org/10.3174/ajnr.A8726
Adam W. Autry
From the Department of Radiology and Biomedical Imaging (A.W.A., Y.K., D.D., H.C., J.B.S., R.A.B., D.X., J.M.L., J.W.G., P.E.Z.L., D.B.V., Y.L.), Department of Neurological Surgery (D.B.V., S.M.C.), Department of Bioengineering and Therapeutic Sciences (D.B.V.) University of California San Francisco, San Francisco, CA, USA
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Yaewon Kim
From the Department of Radiology and Biomedical Imaging (A.W.A., Y.K., D.D., H.C., J.B.S., R.A.B., D.X., J.M.L., J.W.G., P.E.Z.L., D.B.V., Y.L.), Department of Neurological Surgery (D.B.V., S.M.C.), Department of Bioengineering and Therapeutic Sciences (D.B.V.) University of California San Francisco, San Francisco, CA, USA
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Duy Dang
From the Department of Radiology and Biomedical Imaging (A.W.A., Y.K., D.D., H.C., J.B.S., R.A.B., D.X., J.M.L., J.W.G., P.E.Z.L., D.B.V., Y.L.), Department of Neurological Surgery (D.B.V., S.M.C.), Department of Bioengineering and Therapeutic Sciences (D.B.V.) University of California San Francisco, San Francisco, CA, USA
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Hsin-Yu Chen
From the Department of Radiology and Biomedical Imaging (A.W.A., Y.K., D.D., H.C., J.B.S., R.A.B., D.X., J.M.L., J.W.G., P.E.Z.L., D.B.V., Y.L.), Department of Neurological Surgery (D.B.V., S.M.C.), Department of Bioengineering and Therapeutic Sciences (D.B.V.) University of California San Francisco, San Francisco, CA, USA
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James B. Slater
From the Department of Radiology and Biomedical Imaging (A.W.A., Y.K., D.D., H.C., J.B.S., R.A.B., D.X., J.M.L., J.W.G., P.E.Z.L., D.B.V., Y.L.), Department of Neurological Surgery (D.B.V., S.M.C.), Department of Bioengineering and Therapeutic Sciences (D.B.V.) University of California San Francisco, San Francisco, CA, USA
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Robert A. Bok
From the Department of Radiology and Biomedical Imaging (A.W.A., Y.K., D.D., H.C., J.B.S., R.A.B., D.X., J.M.L., J.W.G., P.E.Z.L., D.B.V., Y.L.), Department of Neurological Surgery (D.B.V., S.M.C.), Department of Bioengineering and Therapeutic Sciences (D.B.V.) University of California San Francisco, San Francisco, CA, USA
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Duan Xu
From the Department of Radiology and Biomedical Imaging (A.W.A., Y.K., D.D., H.C., J.B.S., R.A.B., D.X., J.M.L., J.W.G., P.E.Z.L., D.B.V., Y.L.), Department of Neurological Surgery (D.B.V., S.M.C.), Department of Bioengineering and Therapeutic Sciences (D.B.V.) University of California San Francisco, San Francisco, CA, USA
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Janine M. Lupo
From the Department of Radiology and Biomedical Imaging (A.W.A., Y.K., D.D., H.C., J.B.S., R.A.B., D.X., J.M.L., J.W.G., P.E.Z.L., D.B.V., Y.L.), Department of Neurological Surgery (D.B.V., S.M.C.), Department of Bioengineering and Therapeutic Sciences (D.B.V.) University of California San Francisco, San Francisco, CA, USA
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Jeremy W. Gordon
From the Department of Radiology and Biomedical Imaging (A.W.A., Y.K., D.D., H.C., J.B.S., R.A.B., D.X., J.M.L., J.W.G., P.E.Z.L., D.B.V., Y.L.), Department of Neurological Surgery (D.B.V., S.M.C.), Department of Bioengineering and Therapeutic Sciences (D.B.V.) University of California San Francisco, San Francisco, CA, USA
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Peder E.Z. Larson
From the Department of Radiology and Biomedical Imaging (A.W.A., Y.K., D.D., H.C., J.B.S., R.A.B., D.X., J.M.L., J.W.G., P.E.Z.L., D.B.V., Y.L.), Department of Neurological Surgery (D.B.V., S.M.C.), Department of Bioengineering and Therapeutic Sciences (D.B.V.) University of California San Francisco, San Francisco, CA, USA
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Daniel B. Vigneron
From the Department of Radiology and Biomedical Imaging (A.W.A., Y.K., D.D., H.C., J.B.S., R.A.B., D.X., J.M.L., J.W.G., P.E.Z.L., D.B.V., Y.L.), Department of Neurological Surgery (D.B.V., S.M.C.), Department of Bioengineering and Therapeutic Sciences (D.B.V.) University of California San Francisco, San Francisco, CA, USA
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Yan Li
From the Department of Radiology and Biomedical Imaging (A.W.A., Y.K., D.D., H.C., J.B.S., R.A.B., D.X., J.M.L., J.W.G., P.E.Z.L., D.B.V., Y.L.), Department of Neurological Surgery (D.B.V., S.M.C.), Department of Bioengineering and Therapeutic Sciences (D.B.V.) University of California San Francisco, San Francisco, CA, USA
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Susan M. Chang
From the Department of Radiology and Biomedical Imaging (A.W.A., Y.K., D.D., H.C., J.B.S., R.A.B., D.X., J.M.L., J.W.G., P.E.Z.L., D.B.V., Y.L.), Department of Neurological Surgery (D.B.V., S.M.C.), Department of Bioengineering and Therapeutic Sciences (D.B.V.) University of California San Francisco, San Francisco, CA, USA
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Article Information

ajnr.A8726
DOI 
https://doi.org/10.3174/ajnr.A8726
PubMed 
40044455

Published By 
American Journal of Neuroradiology
Print ISSN 
0195-6108
Online ISSN 
1936-959X
History 
  • Published online March 5, 2025.

Copyright & Usage 
© 2025 by American Journal of Neuroradiology

Author Information

  1. Adam W. Autry,
  2. Yaewon Kim,
  3. Duy Dang,
  4. Hsin-Yu Chen,
  5. James B. Slater,
  6. Robert A. Bok,
  7. Duan Xu,
  8. Janine M. Lupo,
  9. Jeremy W. Gordon,
  10. Peder E.Z. Larson,
  11. Daniel B. Vigneron,
  12. Yan Li and
  13. Susan M. Chang
  1. From the Department of Radiology and Biomedical Imaging (A.W.A., Y.K., D.D., H.C., J.B.S., R.A.B., D.X., J.M.L., J.W.G., P.E.Z.L., D.B.V., Y.L.), Department of Neurological Surgery (D.B.V., S.M.C.), Department of Bioengineering and Therapeutic Sciences (D.B.V.) University of California San Francisco, San Francisco, CA, USA
  1. Please address correspondence to Adam W. Autry, PhD, Department of Radiology and Biomedical Imaging, University of California San Francisco, 550 16th St., San Francisco, CA, 94158, USA address; adam.autry{at}ucsf.edu.

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Cite this article
Accepted Manuscript
Adam W. Autry, Yaewon Kim, Duy Dang, Hsin-Yu Chen, James B. Slater, Robert A. Bok, Duan Xu, Janine M. Lupo, Jeremy W. Gordon, Peder E.Z. Larson, Daniel B. Vigneron, Yan Li, Susan M. Chang
Clinical Translation of Hyperpolarized 13C Metabolic Probes for Glioma Imaging
American Journal of Neuroradiology Mar 2025, ajnr.A8726; DOI: 10.3174/ajnr.A8726

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Accepted Manuscript
Clinical Translation of Hyperpolarized 13C Metabolic Probes for Glioma Imaging
Adam W. Autry, Yaewon Kim, Duy Dang, Hsin-Yu Chen, James B. Slater, Robert A. Bok, Duan Xu, Janine M. Lupo, Jeremy W. Gordon, Peder E.Z. Larson, Daniel B. Vigneron, Yan Li, Susan M. Chang
American Journal of Neuroradiology Mar 2025, ajnr.A8726; DOI: 10.3174/ajnr.A8726
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