“Synthetic” DSC perfusion MRI with adjustable acquisition parameters in brain tumors using dynamic spin-and-gradient-echo echoplanar imaging

From the UCLA Brain Tumor Imaging Laboratory (BTIL), Center for Computer Vision and Imaging Biomarkers, and Department of Radiological Sciences, (F.S., J.Y., N.S.C., C.R., B.M.E.), Department of Neurosurgery (R.G.E., B.M.E.), Department of Neurology (T.F.C.), Department of Radiological Sciences (W.B.P., N.S.), Department of Psychiatry and Biobehavioral Sciences (B.M.E.), Medical Scientist Training Program (N.S.C.), David Geffen School of Medicine, Department of Bioengineering, Henry Samueli School of Engineering and Applied Science (N.S.C., B.M.E.), Department of Biostatistics (D.T.), University of California Los Angeles, Los Angeles, CA, USA; from the Department of Diagnostic Imaging (J.L.B.), Warren Alpert Medical School, Brown University, Providence, RI, USA.

From the UCLA Brain Tumor Imaging Laboratory (BTIL), Center for Computer Vision and Imaging Biomarkers, and Department of Radiological Sciences, (F.S., J.Y., N.S.C., C.R., B.M.E.), Department of Neurosurgery (R.G.E., B.M.E.), Department of Neurology (T.F.C.), Department of Radiological Sciences (W.B.P., N.S.), Department of Psychiatry and Biobehavioral Sciences (B.M.E.), Medical Scientist Training Program (N.S.C.), David Geffen School of Medicine, Department of Bioengineering, Henry Samueli School of Engineering and Applied Science (N.S.C., B.M.E.), Department of Biostatistics (D.T.), University of California Los Angeles, Los Angeles, CA, USA; from the Department of Diagnostic Imaging (J.L.B.), Warren Alpert Medical School, Brown University, Providence, RI, USA.

From the UCLA Brain Tumor Imaging Laboratory (BTIL), Center for Computer Vision and Imaging Biomarkers, and Department of Radiological Sciences, (F.S., J.Y., N.S.C., C.R., B.M.E.), Department of Neurosurgery (R.G.E., B.M.E.), Department of Neurology (T.F.C.), Department of Radiological Sciences (W.B.P., N.S.), Department of Psychiatry and Biobehavioral Sciences (B.M.E.), Medical Scientist Training Program (N.S.C.), David Geffen School of Medicine, Department of Bioengineering, Henry Samueli School of Engineering and Applied Science (N.S.C., B.M.E.), Department of Biostatistics (D.T.), University of California Los Angeles, Los Angeles, CA, USA; from the Department of Diagnostic Imaging (J.L.B.), Warren Alpert Medical School, Brown University, Providence, RI, USA.

From the UCLA Brain Tumor Imaging Laboratory (BTIL), Center for Computer Vision and Imaging Biomarkers, and Department of Radiological Sciences, (F.S., J.Y., N.S.C., C.R., B.M.E.), Department of Neurosurgery (R.G.E., B.M.E.), Department of Neurology (T.F.C.), Department of Radiological Sciences (W.B.P., N.S.), Department of Psychiatry and Biobehavioral Sciences (B.M.E.), Medical Scientist Training Program (N.S.C.), David Geffen School of Medicine, Department of Bioengineering, Henry Samueli School of Engineering and Applied Science (N.S.C., B.M.E.), Department of Biostatistics (D.T.), University of California Los Angeles, Los Angeles, CA, USA; from the Department of Diagnostic Imaging (J.L.B.), Warren Alpert Medical School, Brown University, Providence, RI, USA.

From the UCLA Brain Tumor Imaging Laboratory (BTIL), Center for Computer Vision and Imaging Biomarkers, and Department of Radiological Sciences, (F.S., J.Y., N.S.C., C.R., B.M.E.), Department of Neurosurgery (R.G.E., B.M.E.), Department of Neurology (T.F.C.), Department of Radiological Sciences (W.B.P., N.S.), Department of Psychiatry and Biobehavioral Sciences (B.M.E.), Medical Scientist Training Program (N.S.C.), David Geffen School of Medicine, Department of Bioengineering, Henry Samueli School of Engineering and Applied Science (N.S.C., B.M.E.), Department of Biostatistics (D.T.), University of California Los Angeles, Los Angeles, CA, USA; from the Department of Diagnostic Imaging (J.L.B.), Warren Alpert Medical School, Brown University, Providence, RI, USA.

From the UCLA Brain Tumor Imaging Laboratory (BTIL), Center for Computer Vision and Imaging Biomarkers, and Department of Radiological Sciences, (F.S., J.Y., N.S.C., C.R., B.M.E.), Department of Neurosurgery (R.G.E., B.M.E.), Department of Neurology (T.F.C.), Department of Radiological Sciences (W.B.P., N.S.), Department of Psychiatry and Biobehavioral Sciences (B.M.E.), Medical Scientist Training Program (N.S.C.), David Geffen School of Medicine, Department of Bioengineering, Henry Samueli School of Engineering and Applied Science (N.S.C., B.M.E.), Department of Biostatistics (D.T.), University of California Los Angeles, Los Angeles, CA, USA; from the Department of Diagnostic Imaging (J.L.B.), Warren Alpert Medical School, Brown University, Providence, RI, USA.

From the UCLA Brain Tumor Imaging Laboratory (BTIL), Center for Computer Vision and Imaging Biomarkers, and Department of Radiological Sciences, (F.S., J.Y., N.S.C., C.R., B.M.E.), Department of Neurosurgery (R.G.E., B.M.E.), Department of Neurology (T.F.C.), Department of Radiological Sciences (W.B.P., N.S.), Department of Psychiatry and Biobehavioral Sciences (B.M.E.), Medical Scientist Training Program (N.S.C.), David Geffen School of Medicine, Department of Bioengineering, Henry Samueli School of Engineering and Applied Science (N.S.C., B.M.E.), Department of Biostatistics (D.T.), University of California Los Angeles, Los Angeles, CA, USA; from the Department of Diagnostic Imaging (J.L.B.), Warren Alpert Medical School, Brown University, Providence, RI, USA.

From the UCLA Brain Tumor Imaging Laboratory (BTIL), Center for Computer Vision and Imaging Biomarkers, and Department of Radiological Sciences, (F.S., J.Y., N.S.C., C.R., B.M.E.), Department of Neurosurgery (R.G.E., B.M.E.), Department of Neurology (T.F.C.), Department of Radiological Sciences (W.B.P., N.S.), Department of Psychiatry and Biobehavioral Sciences (B.M.E.), Medical Scientist Training Program (N.S.C.), David Geffen School of Medicine, Department of Bioengineering, Henry Samueli School of Engineering and Applied Science (N.S.C., B.M.E.), Department of Biostatistics (D.T.), University of California Los Angeles, Los Angeles, CA, USA; from the Department of Diagnostic Imaging (J.L.B.), Warren Alpert Medical School, Brown University, Providence, RI, USA.

From the UCLA Brain Tumor Imaging Laboratory (BTIL), Center for Computer Vision and Imaging Biomarkers, and Department of Radiological Sciences, (F.S., J.Y., N.S.C., C.R., B.M.E.), Department of Neurosurgery (R.G.E., B.M.E.), Department of Neurology (T.F.C.), Department of Radiological Sciences (W.B.P., N.S.), Department of Psychiatry and Biobehavioral Sciences (B.M.E.), Medical Scientist Training Program (N.S.C.), David Geffen School of Medicine, Department of Bioengineering, Henry Samueli School of Engineering and Applied Science (N.S.C., B.M.E.), Department of Biostatistics (D.T.), University of California Los Angeles, Los Angeles, CA, USA; from the Department of Diagnostic Imaging (J.L.B.), Warren Alpert Medical School, Brown University, Providence, RI, USA.

From the UCLA Brain Tumor Imaging Laboratory (BTIL), Center for Computer Vision and Imaging Biomarkers, and Department of Radiological Sciences, (F.S., J.Y., N.S.C., C.R., B.M.E.), Department of Neurosurgery (R.G.E., B.M.E.), Department of Neurology (T.F.C.), Department of Radiological Sciences (W.B.P., N.S.), Department of Psychiatry and Biobehavioral Sciences (B.M.E.), Medical Scientist Training Program (N.S.C.), David Geffen School of Medicine, Department of Bioengineering, Henry Samueli School of Engineering and Applied Science (N.S.C., B.M.E.), Department of Biostatistics (D.T.), University of California Los Angeles, Los Angeles, CA, USA; from the Department of Diagnostic Imaging (J.L.B.), Warren Alpert Medical School, Brown University, Providence, RI, USA.

From the UCLA Brain Tumor Imaging Laboratory (BTIL), Center for Computer Vision and Imaging Biomarkers, and Department of Radiological Sciences, (F.S., J.Y., N.S.C., C.R., B.M.E.), Department of Neurosurgery (R.G.E., B.M.E.), Department of Neurology (T.F.C.), Department of Radiological Sciences (W.B.P., N.S.), Department of Psychiatry and Biobehavioral Sciences (B.M.E.), Medical Scientist Training Program (N.S.C.), David Geffen School of Medicine, Department of Bioengineering, Henry Samueli School of Engineering and Applied Science (N.S.C., B.M.E.), Department of Biostatistics (D.T.), University of California Los Angeles, Los Angeles, CA, USA; from the Department of Diagnostic Imaging (J.L.B.), Warren Alpert Medical School, Brown University, Providence, RI, USA.