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Research ArticleNEUROINTERVENTION

Modeling Robotic-Assisted Mechanical Thrombectomy Procedures with the CorPath GRX Robot: The Core-Flow Study

Alejandro Tomasello, David Hernández, Jiahui Li, Riccardo Tiberi, Eila Rivera, Joan Daniel Vargas, Cristina Losada, Magda Jablonska, Marielle Esteves, Maria Lourdes Diaz, Judith Cendrero, Manuel Requena, Francesco Diana, Marta De Dios, Trisha Singh, Laura Ludovica Gramegna and Marc Ribo
American Journal of Neuroradiology April 2024, DOI: https://doi.org/10.3174/ajnr.A8205
Alejandro Tomasello
aFrom the Interventional Neuroradiology Section (A.T., D.H., J.D.V., C.L., M. Requena, F.D., M.D.D., T.S.), Vall d’Hebron Barcelona Hospital Campus, Barcelona, Spain.
bDepartamento de Medicina (A.T.), Universitat Autònoma de Barcelona, Barcelona, Spain.
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David Hernández
aFrom the Interventional Neuroradiology Section (A.T., D.H., J.D.V., C.L., M. Requena, F.D., M.D.D., T.S.), Vall d’Hebron Barcelona Hospital Campus, Barcelona, Spain.
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  • ORCID record for David Hernández
Jiahui Li
cStroke Research (J.L., RT., M.J., J.C., M. Requena, M. Ribo), Vall d'Hebron Institut de Recerca, Vall d'Hebron Barcelona Hospital Campus, Barcelona, Spain.
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Riccardo Tiberi
cStroke Research (J.L., RT., M.J., J.C., M. Requena, M. Ribo), Vall d'Hebron Institut de Recerca, Vall d'Hebron Barcelona Hospital Campus, Barcelona, Spain.
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  • ORCID record for Riccardo Tiberi
Eila Rivera
dVall d'Hebron Institut de Recerca (E.R., F.D., L.L.G.), Vall d'Hebron Barcelona Hospital Campus, Barcelona, Spain.
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Joan Daniel Vargas
aFrom the Interventional Neuroradiology Section (A.T., D.H., J.D.V., C.L., M. Requena, F.D., M.D.D., T.S.), Vall d’Hebron Barcelona Hospital Campus, Barcelona, Spain.
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Cristina Losada
aFrom the Interventional Neuroradiology Section (A.T., D.H., J.D.V., C.L., M. Requena, F.D., M.D.D., T.S.), Vall d’Hebron Barcelona Hospital Campus, Barcelona, Spain.
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Magda Jablonska
cStroke Research (J.L., RT., M.J., J.C., M. Requena, M. Ribo), Vall d'Hebron Institut de Recerca, Vall d'Hebron Barcelona Hospital Campus, Barcelona, Spain.
f2nd Department of Radiology (M.J.), Medical University of Gdańsk, Gdańsk, Poland.
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  • ORCID record for Magda Jablonska
Marielle Esteves
gExperimental Surgery Unit (M.E.), Vall d’Hebron Research Institute, Vall d’Hebron Barcelona Hospital Campus, Barcelona, Spain.
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Maria Lourdes Diaz
hDepartament De Radiologia Vascular Interventista (M.L.D.), Hospital General Universitario Arnau de Villanova, Lleida, Spain
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Judith Cendrero
cStroke Research (J.L., RT., M.J., J.C., M. Requena, M. Ribo), Vall d'Hebron Institut de Recerca, Vall d'Hebron Barcelona Hospital Campus, Barcelona, Spain.
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Manuel Requena
aFrom the Interventional Neuroradiology Section (A.T., D.H., J.D.V., C.L., M. Requena, F.D., M.D.D., T.S.), Vall d’Hebron Barcelona Hospital Campus, Barcelona, Spain.
cStroke Research (J.L., RT., M.J., J.C., M. Requena, M. Ribo), Vall d'Hebron Institut de Recerca, Vall d'Hebron Barcelona Hospital Campus, Barcelona, Spain.
eStroke Unit (M. Requena, M. Ribo), Neurology Department Vall d’Hebron Barcelona Hospital Campus, Barcelona, Spain.
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Francesco Diana
aFrom the Interventional Neuroradiology Section (A.T., D.H., J.D.V., C.L., M. Requena, F.D., M.D.D., T.S.), Vall d’Hebron Barcelona Hospital Campus, Barcelona, Spain.
dVall d'Hebron Institut de Recerca (E.R., F.D., L.L.G.), Vall d'Hebron Barcelona Hospital Campus, Barcelona, Spain.
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Marta De Dios
aFrom the Interventional Neuroradiology Section (A.T., D.H., J.D.V., C.L., M. Requena, F.D., M.D.D., T.S.), Vall d’Hebron Barcelona Hospital Campus, Barcelona, Spain.
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Trisha Singh
aFrom the Interventional Neuroradiology Section (A.T., D.H., J.D.V., C.L., M. Requena, F.D., M.D.D., T.S.), Vall d’Hebron Barcelona Hospital Campus, Barcelona, Spain.
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Laura Ludovica Gramegna
dVall d'Hebron Institut de Recerca (E.R., F.D., L.L.G.), Vall d'Hebron Barcelona Hospital Campus, Barcelona, Spain.
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Marc Ribo
bDepartamento de Medicina (A.T.), Universitat Autònoma de Barcelona, Barcelona, Spain.
cStroke Research (J.L., RT., M.J., J.C., M. Requena, M. Ribo), Vall d'Hebron Institut de Recerca, Vall d'Hebron Barcelona Hospital Campus, Barcelona, Spain.
eStroke Unit (M. Requena, M. Ribo), Neurology Department Vall d’Hebron Barcelona Hospital Campus, Barcelona, Spain.
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Figures

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    Fig 1.

    A benchtop 3D printed vascular model with a thrombus inside (A) was connected to a Corindus CorPath GRX robot (B, arrowhead), and MT was performed using SRs (C).

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    Fig 2.

    Experimental setup for robot-assisted and manual EVTs.

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    Fig 3.

    Boxplot analysis shows the difference in median values of various outcomes of thrombectomy (such as recanalization rate, procedural length, and distal emboli generation) when comparing all RA-EVTs and all MA-EVTs. FPE indicates first-pass effect.

  • Fig 4.
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    Fig 4.

    Boxplot analysis shows the difference in median values of various outcomes of thrombectomy (such as recanalization rate, procedural length, and distal emboli generation) when comparing robotic-EVT performed by a robotic-experienced interventional neuroradiologist and robotic-EVT performed by a robot-novice interventional neuroradiologist. FPE indicates first-pass effect.

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Cite this article
Alejandro Tomasello, David Hernández, Jiahui Li, Riccardo Tiberi, Eila Rivera, Joan Daniel Vargas, Cristina Losada, Magda Jablonska, Marielle Esteves, Maria Lourdes Diaz, Judith Cendrero, Manuel Requena, Francesco Diana, Marta De Dios, Trisha Singh, Laura Ludovica Gramegna, Marc Ribo
Modeling Robotic-Assisted Mechanical Thrombectomy Procedures with the CorPath GRX Robot: The Core-Flow Study
American Journal of Neuroradiology Apr 2024, DOI: 10.3174/ajnr.A8205

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Modeling Robotic-Assisted Mechanical Thrombectomy Procedures with the CorPath GRX Robot: The Core-Flow Study
Alejandro Tomasello, David Hernández, Jiahui Li, Riccardo Tiberi, Eila Rivera, Joan Daniel Vargas, Cristina Losada, Magda Jablonska, Marielle Esteves, Maria Lourdes Diaz, Judith Cendrero, Manuel Requena, Francesco Diana, Marta De Dios, Trisha Singh, Laura Ludovica Gramegna, Marc Ribo
American Journal of Neuroradiology Apr 2024, DOI: 10.3174/ajnr.A8205
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  • Robotic Stroke Thrombectomy: A Feasibility and Efficacy Study in Flow Models
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