High-Grade Astrocytoma with Piloid Features: A Dual Institutional Review of Imaging Findings of a Novel Entity

References

1. 1.↵
   1. Osborn AG,
   2. Louis DN,
   3. Poussaint TY, et al

   . The 2021 World Health Organization Classification of Tumors of the Central Nervous System: what neuroradiologists need to know. AJNR Am J Neuroradiol 2022;43:928–37 doi:10.3174/ajnr.A7462 pmid:35710121

   Abstract/FREE Full TextGoogle Scholar
2. 2.↵
   1. Rigsby RK,
   2. Brahmbhatt P,
   3. Desai AB, et al

   . Newly recognized CNS tumors in the 2021 World Health Organization Classification: imaging overview with histopathologic and genetic correlation. AJNR Am J Neuroradiol 2023;44:367–80 doi:10.3174/ajnr.A7827 pmid:36997287

   Abstract/FREE Full TextGoogle Scholar
3. 3.↵
   1. Capper D,
   2. Jones DTW,
   3. Sill M, et al

   . DNA methylation-based classification of central nervous system tumours. Nature 2018;555:469–74 doi:10.1038/nature26000 pmid:29539639

   CrossRefPubMedGoogle Scholar
4. 4.↵
   1. Reinhardt A,
   2. Stichel D,
   3. Schrimpf D, et al

   . Anaplastic astrocytoma with piloid features, a novel molecular class of IDH wildtype glioma with recurrent MAPK pathway, CDKN2A/B and ATRX alterations. Acta Neuropathol 2018;136:273–91 doi:10.1007/s00401-018-1837-8 pmid:29564591

   CrossRefPubMedGoogle Scholar
5. 5.↵
   1. Louis DN,
   2. Perry A,
   3. Wesseling P, et al

   . The 2021 WHO Classification of Tumors of the Central Nervous System: a summary. Neuro Oncol 2021;23:1231–51 doi:10.1093/neuonc/noab106 pmid:34185076

   CrossRefPubMedGoogle Scholar
6. 6.↵
   1. Cimino PJ,
   2. Ketchum C,
   3. Turakulov R, et al

   . Expanded analysis of high-grade astrocytoma with piloid features identifies an epigenetically and clinically distinct subtype associated with neurofibromatosis type 1. Acta Neuropathol 2023;145:71–82 doi:10.1007/s00401-022-02513-5 pmid:36271929

   CrossRefPubMedGoogle Scholar
7. 7.↵
   1. Bender K,
   2. Perez E,
   3. Chirica M, et al

   . High-grade astrocytoma with piloid features (HGAP): the Charité experience with a new central nervous system tumor entity. J Neurooncol 2021;153:109–20 doi:10.1007/s11060-021-03749-z pmid:33905054

   CrossRefPubMedGoogle Scholar
8. 8.↵
   1. Reinhardt A,
   2. Stichel D,
   3. Schrimpf D, et al

   . Tumors diagnosed as cerebellar glioblastoma comprise distinct molecular entities. Acta Neuropathol Commun 2019;7:163 doi:10.1186/s40478-019-0801-8 pmid:31661039

   CrossRefPubMedGoogle Scholar
9. 9.↵
   1. Kleinschmidt-DeMasters BK,
   2. Ormond DR

   . Leptomeningeal metastases and dural spread in adult high-grade astrocytomas. J Neuropathol Exp Neurol 2023;82:194–201 doi:10.1093/jnen/nlac126 pmid:36637258

   CrossRefPubMedGoogle Scholar
10. 10.↵
    1. Miguel Llordes G,
    2. Medina Pérez VM,
    3. Curto Simón B, et al

    . Epidemiology, diagnostic strategies, and therapeutic advances in diffuse midline glioma. J Clin Med 2023;12:5261 doi:10.3390/jcm12165261 pmid:37629304

    CrossRefPubMedGoogle Scholar
11. 11.↵
    1. Maruoka R,
    2. Takenouchi T,
    3. Torii C, et al

    . The use of next-generation sequencing in molecular diagnosis of neurofibromatosis type 1: a validation study. Genet Test Mol Biomarkers 2014;18:722–35 doi:10.1089/gtmb.2014.0109 pmid:25325900

    CrossRefPubMedGoogle Scholar
12. 12.↵
    1. Yamashita K,
    2. Hiwatashi A,
    3. Togao O, et al

    . MR imaging–based analysis of glioblastoma multiforme: estimation of IDH1 mutation status. AJNR Am J Neuroradiol 2016;37:58–65 doi:10.3174/ajnr.A4491 pmid:26405082

    Abstract/FREE Full TextGoogle Scholar
13. 13.↵
    1. Lucas CH,
    2. Sloan EA,
    3. Gupta R, et al

    . Multiplatform molecular analyses refine classification of gliomas arising in patients with neurofibromatosis type 1. Acta Neuropathol 2022;144:747–65 doi:10.1007/s00401-022-02478-5 pmid:35945463

    CrossRefPubMedGoogle Scholar
14. 14.↵
    1. Lobbous M,
    2. Bernstock JD,
    3. Coffee E, et al

    . An update on neurofibromatosis type 1-associated gliomas. Cancers (Basel) 2020;12:12 doi:10.3390/cancers12010114 pmid:31906320

    CrossRefPubMedGoogle Scholar
15. 15.↵
    1. Tao J,
    2. Sun D,
    3. Dong L, et al

    . Advancement in research and therapy of NF1 mutant malignant tumors. Cancer Cell Int 2020;20:492 doi:10.1186/s12935-020-01570-8 pmid:33061844

    CrossRefPubMedGoogle Scholar
16. 16.↵
    1. Romo CG,
    2. Piotrowski AF,
    3. Campian JL, et al

    . Clinical, histological, and molecular features of gliomas in adults with neurofibromatosis type 1. Neuro Oncol 2023;25:1474–86 doi:10.1093/neuonc/noad033 pmid:36840626

    CrossRefPubMedGoogle Scholar
17. 17.↵
    1. Russo C,
    2. Russo C,
    3. Cascone D, et al

    . Non-oncological neuroradiological manifestations in NF1 and their clinical implications. Cancers (Basel) 2021;13:1831 doi:10.3390/cancers13081831 pmid:33921292

    CrossRefPubMedGoogle Scholar
18. 18.↵
    1. Galbraith K,
    2. Snuderl M

    . DNA methylation as a diagnostic tool. Acta Neuropathol Commun 2022;10:71 doi:10.1186/s40478-022-01371-2 pmid:35527288

    CrossRefPubMedGoogle Scholar
19. 19.↵
    1. Haase S,
    2. Garcia-Fabiani MB,
    3. Carney S, et al

    . Mutant ATRX: uncovering a new therapeutic target for glioma. Expert Opin Ther Targets 2018;22:599–613 doi:10.1080/14728222.2018.1487953 pmid:29889582

    CrossRefPubMedGoogle Scholar
20. 20.↵
    1. Collins VP,
    2. Jones DT,
    3. Giannini C

    . Pilocytic astrocytoma: pathology, molecular mechanisms and markers. Acta Neuropathol 2015;129:775–88 doi:10.1007/s00401-015-1410-7 pmid:25792358

    CrossRefPubMedGoogle Scholar
21. 21.↵
    1. Jones DT,
    2. Hutter B,
    3. Jäger N, et al

    ; International Cancer Genome Consortium PedBrain Tumor Project. Recurrent somatic alterations of FGFR1 and NTRK2 in pilocytic astrocytoma. Nat Genet 2013;45:927–32 doi:10.1038/ng.2682 pmid:23817572

    CrossRefPubMedGoogle Scholar
22. 22.↵
    1. Marker DF,
    2. Agnihotri S,
    3. Amankulor N, et al

    . The dominant TP53 hotspot mutation in IDH-mutant astrocytoma, R273C, has distinctive pathologic features and sex-specific prognostic implications. Neurooncol Adv 2022;4:vdab182 doi:10.1093/noajnl/vdab182 pmid:35047821

    CrossRefPubMedGoogle Scholar
23. 23.↵
    1. Fontebasso AM,
    2. Schwartzentruber J,
    3. Khuong-Quang DA, et al

    . Mutations in SETD2 and genes affecting histone H3K36 methylation target hemispheric high-grade gliomas. Acta Neuropathol 2013;125:659–69 doi:10.1007/s00401-013-1095-8 pmid:23417712

    CrossRefPubMedGoogle Scholar
24. 24.↵
    1. Nomura M,
    2. Mukasa A,
    3. Nagae G, et al

    . Distinct molecular profile of diffuse cerebellar gliomas. Acta Neuropathol 2017;134:941–56 doi:10.1007/s00401-017-1771-1 pmid:28852847

    CrossRefPubMedGoogle Scholar
25. 25.↵
    1. Theeler BJ,
    2. Ellezam B,
    3. Sadighi ZS, et al

    . Adult pilocytic astrocytomas: clinical features and molecular analysis. Neuro Oncol 2014;16:841–47 doi:10.1093/neuonc/not246 pmid:24470550

    CrossRefPubMedGoogle Scholar
26. 26.↵
    1. Chourmouzi D,
    2. Papadopoulou E,
    3. Konstantinidis M, et al

    . Manifestations of pilocytic astrocytoma: a pictorial review. Insights Imaging 2014;5:387–402 doi:10.1007/s13244-014-0328-2 pmid:24789122

    CrossRefPubMedGoogle Scholar
27. 27.↵
    1. Zhao JP,
    2. Liu XJ,
    3. Lin HZ, et al

    . MRI comparative study of diffuse midline glioma, H3 K27-altered and glioma in the midline without H3 K27-altered. BMC Neurol 2022;22:498 doi:10.1186/s12883-022-03026-0 pmid:36550486

    CrossRefPubMedGoogle Scholar
28. 28.↵
    1. Vallero SG,
    2. Bertero L,
    3. Morana G, et al

    . Pediatric diffuse midline glioma H3K27-altered: A complex clinical and biological landscape behind a neatly defined tumor type. Front Oncol 2022;12:1082062 doi:10.3389/fonc.2022.1082062 pmid:36727064

    CrossRefPubMedGoogle Scholar
29. 29.↵
    1. Aboian MS,
    2. Solomon DA,
    3. Felton E, et al

    . Imaging characteristics of pediatric diffuse midline gliomas with histone H3 K27M mutation. AJNR Am J Neuroradiol 2017;38:795–800 doi:10.3174/ajnr.A5076 pmid:28183840

    Abstract/FREE Full TextGoogle Scholar