Article Figures & Data
Figures
- FIG 1.
Representative MPRAGE, MP2RAGE-UNI, and T1-mapping images of the Hb from a healthy man 30 years of age (black arrow). Visual contrast between the Hb and the thalamus in UNI is better than that in MPRAGE.
- FIG 2.
The Hb ROI was chosen on the basis of the largest axial image on MP2RAGE-UNI and MPRAGE, and the thalamus ROI was defined as twice the size of the Hb ROI, which is located on the anterolateral side of the Hb ROI (first row). The CNR (middle row) and SNR (third row) of UNI is statistically higher than those of MPRAGE (paired samples t test). Radio indicates radiologist.
- FIG 3.
Segmentations from 5 atlases are propagated via image registration to 21 selected template images before being propagated using image registration to each UNI and MPRAGE. This feature creates a large number (5 atlases × 21 templates = 105) of candidate segmentations that are fused using majority vote. This has 2 advantages: reducing atlas bias and averaging registration errors. Also, because the procedure is based on image registration rather than on contrast-based segmentation, it allows the neuroanatomic variability of the subjects to refine each individual subject’s final segmentation. Reg_result indicates registration result.
- FIG 4.
ROI on the T1 mapping from the left-to-right Hb of a representative participant. A, Anterior (red) and posterior (green) subregions within the habenula. B, Medial (pink) and lateral (yellow) subregions within the Hb. C and D, The T1 values of the posterior halves of the Hb are higher than those in the anterior halves, and the medial halves are higher than those in the lateral halves.
- FIG 5.
Bland-Altman plot showing the volume differences of the right Hb (green dots) and left Hb (red dots) between the MAGeTbrain and manual segmentations in the first scan for MPR2RAGE-UNI and MPRAGE. Radio indicates radiologist.
