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Improved Turnaround Times | Median time to first decision: 12 days

Research ArticleNEUROVASCULAR/STROKE IMAGING

Prevalence of “Ghost Infarct Core” after Endovascular Thrombectomy

Johanna M. Ospel, Nathaniel Rex, Leon Rinkel, Nima Kashani, Brian Buck, Jeremy Rempel, Demetrios Sahlas, Michael E. Kelly, Ron Budzik, Michael Tymianski, Michael D. Hill and Mayank Goyal On behalf of the ESCAPE-NA1 Investigators
American Journal of Neuroradiology January 2024, DOI: https://doi.org/10.3174/ajnr.A8113
Johanna M. Ospel
aFrom the Department of Diagnostic Imaging (J.M.O., M.D.H., M.G.), University of Calgary, Calgary, Alberta, Canada
bDepartment of Clinical Neurosciences (J.M.O., N.R., L.R., M.D.H., M.G.), University of Calgary, Calgary, Alberta, Canada
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  • ORCID record for Johanna M. Ospel
Nathaniel Rex
bDepartment of Clinical Neurosciences (J.M.O., N.R., L.R., M.D.H., M.G.), University of Calgary, Calgary, Alberta, Canada
cDepartment of Diagnostic Imaging (N.R.), Brown University, Providence, Rhode Island
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Leon Rinkel
bDepartment of Clinical Neurosciences (J.M.O., N.R., L.R., M.D.H., M.G.), University of Calgary, Calgary, Alberta, Canada
dDepartment of Neurology (L.R.), Amsterdam University Medical Center, Amsterdam, the Netherlands
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Nima Kashani
eDepartment of Neurosurgery (N.K., M.E.K.), University of Saskatchewan, Saskatoon, Saskatchewan, Canada
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  • ORCID record for Nima Kashani
Brian Buck
fUniversity of Alberta Hospital (B.B., J.R.), Edmonton, Alberta, Canada
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Jeremy Rempel
fUniversity of Alberta Hospital (B.B., J.R.), Edmonton, Alberta, Canada
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Demetrios Sahlas
gMcMaster University (D.S.), Hamilton, Ontario, Canada
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Michael E. Kelly
eDepartment of Neurosurgery (N.K., M.E.K.), University of Saskatchewan, Saskatoon, Saskatchewan, Canada
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  • ORCID record for Michael E. Kelly
Ron Budzik
hOhio Health (R.B.), Riverside Methodist Hospital, Columbus, Ohio
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Michael Tymianski
iNoNO Inc. (M.T.) Toronto, Ontario, Canada
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  • ORCID record for Michael Tymianski
Michael D. Hill
aFrom the Department of Diagnostic Imaging (J.M.O., M.D.H., M.G.), University of Calgary, Calgary, Alberta, Canada
bDepartment of Clinical Neurosciences (J.M.O., N.R., L.R., M.D.H., M.G.), University of Calgary, Calgary, Alberta, Canada
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Mayank Goyal
aFrom the Department of Diagnostic Imaging (J.M.O., M.D.H., M.G.), University of Calgary, Calgary, Alberta, Canada
bDepartment of Clinical Neurosciences (J.M.O., N.R., L.R., M.D.H., M.G.), University of Calgary, Calgary, Alberta, Canada
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Figures

  • FIG 1.
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    FIG 1.

    “Ghost core” infarct volumes (baseline CTP core volume – 24-hour infarct volume) in the 77 patients who had a baseline CTP rCBF >30% volume that was larger than 24-hour final infarct volume. To be considered a “ghost core” in the current analysis, this difference in volumes had to be >10 mL. Individual patient (blue dot). Median “ghost core” volume was 0.4 mL (black horizontal line).

  • FIG 2.
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    FIG 2.

    mRS at 90 days in patients with and without ghost infarct core >10 mL (ie, CBF <30% infarct core at baseline minus infarct volume at 24 hours >10 mL). mRS categories are shown in ascending order from left to right. Note that 4.3%, 0% and 0% patients achieved mRS 4, 5 and 6 respectively in the lower bar.

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Prevalence of “Ghost Infarct Core” after Endovascular Thrombectomy
Johanna M. Ospel, Nathaniel Rex, Leon Rinkel, Nima Kashani, Brian Buck, Jeremy Rempel, Demetrios Sahlas, Michael E. Kelly, Ron Budzik, Michael Tymianski, Michael D. Hill, Mayank Goyal
American Journal of Neuroradiology Jan 2024, DOI: 10.3174/ajnr.A8113
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Johanna M. Ospel, Nathaniel Rex, Leon Rinkel, Nima Kashani, Brian Buck, Jeremy Rempel, Demetrios Sahlas, Michael E. Kelly, Ron Budzik, Michael Tymianski, Michael D. Hill, Mayank Goyal
Prevalence of “Ghost Infarct Core” after Endovascular Thrombectomy
American Journal of Neuroradiology Jan 2024, DOI: 10.3174/ajnr.A8113

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