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Improved Turnaround Times | Median time to first decision: 12 days

Research ArticleNeurointervention

Low-Dose Eptifibatide for Tandem Occlusion in Stroke: Safety and Carotid Artery Patency

A. Jost, C. Roels, M. Brown, R. Janjua and D. Heck
American Journal of Neuroradiology February 2021, DOI: https://doi.org/10.3174/ajnr.A6985
A. Jost
aFrom the Wake Forest School of Medicine (A.J.), Winston Salem, North Carolina
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C. Roels
bDepartments of Pharmacy (C.R.)
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M. Brown
dTriad Radiology Associates (M.B., D.H.), Forsyth Medical Center, Winston Salem, North Carolina
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R. Janjua
cNeurosurgery (R.J.), Novant Health, Forsyth Medical Center, Winston Salem, North Carolina
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D. Heck
dTriad Radiology Associates (M.B., D.H.), Forsyth Medical Center, Winston Salem, North Carolina
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  • FIGURE.
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    FIGURE.

    A, Occlusive internal carotid stenosis at the bifurcation; severe external carotid artery stenosis. B, Angioplasty with a 4-mm balloon. C, After successful intracranial thrombectomy, note severe residual stenosis, D, An 8 × 6 × 30 mm stent was placed. Note occlusion of the external carotid artery (the stent was occluded on sonography the next morning).

Tables

  • Figures
  • Summary of population and results

    Summary
    Age (median) (IQR) (yr)64 (57–76)
    Male (No.) (%)38 (68%)
    Hypertension (No.) (%)41 (71%)
    Diabetes (No.) (%)17 (29%)
    Dyslipidemia (No.) (%)41 (71%)
    Current aspirin use (No.) (%)22 (38%)
    Current clopidogrel use (No.) (%)6 (10%)
    Current/former smoker (No.) (%)22 (38%)/14 (24%)
    Baseline NIHSS (median) (IQR)15 (11–20)
    Baseline ASPECTS 8–10/5–7 (No.) (%)47 (81%)/11 (19%)
    Carotid Terminus occlusion (No.) (%)25 (43%)
    M1 occlusion (No.) (%)22 (38%)
    M2 occlusion, (No.) (%)11 (19%)
    tPA administration (No.) (%)25 (43%)
    Acute angioplasty alone (No.) (%)20 (34%)
    Acute angioplasty and stent placement (No.) (%)38 (66%)
    Delayed stent or endarterectomy within a week (No.) (%)6 (10%)
    mTICI score > 2a (No.) (%)56 (96%)
    Acute carotid artery re-occlusion (No.) (%)4 (7%)
    Any ICH (No.) (%)18 (31%)
    Symptomatic ICH (No.) (%)1 (2%)
    30- to 60-Day carotid patency (No.) (%)42/49 (86%)
    90-Day mRS 0–2 (No.) (%)42 (72%)
    • Note:—IQR indicates interquartile range; ICH, intracranial hemorrhage.

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Low-Dose Eptifibatide for Tandem Occlusion in Stroke: Safety and Carotid Artery Patency
A. Jost, C. Roels, M. Brown, R. Janjua, D. Heck
American Journal of Neuroradiology Feb 2021, DOI: 10.3174/ajnr.A6985
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A. Jost, C. Roels, M. Brown, R. Janjua, D. Heck
Low-Dose Eptifibatide for Tandem Occlusion in Stroke: Safety and Carotid Artery Patency
American Journal of Neuroradiology Feb 2021, DOI: 10.3174/ajnr.A6985

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