Article Figures & Data
Figures
- FIG 1.
Structural images showing voxel localized in the frontal lobe on the midline above the genu of the corpus callosum, to include the anterior cingulate cortex.
- FIG 2.
GABA+- and GSH-edited spectra from participants with a fit error of <15%. GABA+-edited spectra are acquired using both HERMES and MEGA-PRESS sequences.
- FIG 3.
GABA+ and GSH correlations with age. Significant correlations are observed between GABA+ and age, whereas GSH does not significantly correlate with age. r indicates the Pearson correlation coefficient.
Tables
Sample distribution of the pediatric cohort, voxel tissue composition, and metabolite concentrationsa
Parameters No. 23 Sex (male/female) 12/11 Age (yr) 5.6–13.9; 10.2 ± 2.5 Male 5.6–13.9; 9.81 ± 3.01 Female 8.1–13.1; 10.61 ± 1.76 Race (No.) Black/African-American 4 White 16 >1 race 3 Voxel tissue composition Gray matter (%) 51.7 ± 4.8 White matter (%) 31.0 ± 3.5 GMratio (%) 62.5 ± 3.8 Metabolite levels GABA+H2O (i.u.) 2.70–4.37; 3.35 ± 0.48 GABA+/Cr 0.073–0.120; 0.102 ± 0.011 GSHH2O (i.u.) 1.07–1.92; 1.50 ± 0.24 GSH/Cr 0.036–0.058; 0.05 ± 0.006 ↵a Data are minimum–maximum; mean ± SD.
