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Research ArticleNeurointervention

Endovascular Treatment Decisions in Patients with M2 Segment MCA Occlusions

M. Almekhlafi, J.M. Ospel, G. Saposnik, N. Kashani, A. Demchuk, M.D. Hill, M. Goyal and B.K. Menon
American Journal of Neuroradiology January 2020, DOI: https://doi.org/10.3174/ajnr.A6397
M. Almekhlafi
aFrom the Department of Clinical Neurosciences (M.A., J.M.O., A.D., M.D.H., M.G., B.K.M.), Hotchkiss Brain Institute
band Departments of Radiology (M.A., N.K., A.D., M.D.H., M.G., B.K.M.)
cCommunity Health Sciences (M.A., M.D.H., B.K.M.), University of Calgary, Calgary, Alberta, Canada
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  • ORCID record for M. Almekhlafi
J.M. Ospel
aFrom the Department of Clinical Neurosciences (M.A., J.M.O., A.D., M.D.H., M.G., B.K.M.), Hotchkiss Brain Institute
dDepartment of Radiology (J.M.O.), University Hospital Basel, University Basel, Basel, Switzerland
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G. Saposnik
eand Stroke Outcomes and Decision Neuroscience Research Unit (G.S.), Department of Medicine,
fLi Ka Shing Knowledge Institute (G.S.), St. Michael’s Hospital, University of Toronto, Toronto, Ontario, Canada
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  • ORCID record for G. Saposnik
N. Kashani
band Departments of Radiology (M.A., N.K., A.D., M.D.H., M.G., B.K.M.)
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A. Demchuk
aFrom the Department of Clinical Neurosciences (M.A., J.M.O., A.D., M.D.H., M.G., B.K.M.), Hotchkiss Brain Institute
band Departments of Radiology (M.A., N.K., A.D., M.D.H., M.G., B.K.M.)
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M.D. Hill
aFrom the Department of Clinical Neurosciences (M.A., J.M.O., A.D., M.D.H., M.G., B.K.M.), Hotchkiss Brain Institute
band Departments of Radiology (M.A., N.K., A.D., M.D.H., M.G., B.K.M.)
cCommunity Health Sciences (M.A., M.D.H., B.K.M.), University of Calgary, Calgary, Alberta, Canada
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M. Goyal
aFrom the Department of Clinical Neurosciences (M.A., J.M.O., A.D., M.D.H., M.G., B.K.M.), Hotchkiss Brain Institute
band Departments of Radiology (M.A., N.K., A.D., M.D.H., M.G., B.K.M.)
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B.K. Menon
aFrom the Department of Clinical Neurosciences (M.A., J.M.O., A.D., M.D.H., M.G., B.K.M.), Hotchkiss Brain Institute
band Departments of Radiology (M.A., N.K., A.D., M.D.H., M.G., B.K.M.)
cCommunity Health Sciences (M.A., M.D.H., B.K.M.), University of Calgary, Calgary, Alberta, Canada
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Figures

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  • FIG 1.
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    FIG 1.

    Decision rates in favor of EVT for different occlusion locations (A), decision rates in favor of EVT in M2 segment MCA occlusions for different geographic regions (B), for different specialties (C), and hospital settings (D). Blue dots illustrate decision rates under assumed ideal conditions and red dots decision rates under current local resources. Decision rates under current resources and assuming ideal conditions in North America in (B) were identical. Decision rates under current resources for neurosurgeons were lower than under assumed ideal conditions (C).

  • FIG 2.
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    FIG 2.

    Decision rates in favor of EVT in patients with M2 segment MCA occlusions by survey respondents across the globe, stratified by country, under current resources (bars), and assumed ideal conditions (black dots).

Tables

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  • EVT decision rates for M2 segment MCA occlusion case scenarios

    Case VignetteEVT
    Evidence LevelRate under Current Local Resources (%)Rate under Assumed Ideal Conditions (%)
    An 88-year-old, right-handed man has arrived at your hospital at 10:00 am with right hemiparesis and aphasia; symptom onset was 3 hours ago; his stroke severity measured by NIHSS is 14; ASPECTS on noncontrast CT is 7; baseline CTA reveals a proximal left M2 segment MCA occlusion2B81.685.9
    A 45-year-old, left-handed man has arrived at your hospital at 1:00 pm with left hemiparesis and visual field defect; he was last seen as normal 12 hours ago; his stroke severity measured by NIHSS is 15; ASPECTS on noncontrast CT is 8; baseline CTA shows a proximal right M2 segment MCA occlusion2B68.775.3
    A 94-year-old, left-handed woman has arrived at your hospital at 2:00 am with right hemiparesis and aphasia; symptom onset was 3.5 hours ago; her stroke severity measured by NIHSS is 12; ASPECTS on noncontrast CT is 7; the baseline CTA shows a proximal left M2 segment MCA occlusion2B60.3%67.2%
    An 85-year-old, right-handed woman has arrived at your hospital at 11:00 pm with left hemiparesis; symptoms are 3 hours from onset; her stroke severity as measured by NIHSS is 9; ASPECTS on noncontrast CT is 6; baseline CTA shows a proximal right M2 segment MCA occlusion; she has a history of mild cognitive impairment2B62.363.4
    A 56-year-old, right-handed man has arrived at your hospital at 3:00 pm with global aphasia; symptoms are 3 hours from onset; his stroke severity measured by NIHSS is 8; ASPECTS on noncontrast CT is 9; baseline CTA reveals a small-branch left M2 segment MCA occlusion2B53.856.4
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Cite this article
M. Almekhlafi, J.M. Ospel, G. Saposnik, N. Kashani, A. Demchuk, M.D. Hill, M. Goyal, B.K. Menon
Endovascular Treatment Decisions in Patients with M2 Segment MCA Occlusions
American Journal of Neuroradiology Jan 2020, DOI: 10.3174/ajnr.A6397

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Endovascular Treatment Decisions in Patients with M2 Segment MCA Occlusions
M. Almekhlafi, J.M. Ospel, G. Saposnik, N. Kashani, A. Demchuk, M.D. Hill, M. Goyal, B.K. Menon
American Journal of Neuroradiology Jan 2020, DOI: 10.3174/ajnr.A6397
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