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Improved Turnaround Times | Median time to first decision: 12 days

Research ArticleHead and Neck Imaging

Prognostic Implications of Gadolinium Enhancement of Skull Base Chordomas

E. Lin, T. Scognamiglio, Y. Zhao, T.H. Schwartz and C.D. Phillips
American Journal of Neuroradiology June 2018, DOI: https://doi.org/10.3174/ajnr.A5714
E. Lin
aFrom the Departments of Radiology (E.L., C.D.P.)
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T. Scognamiglio
bPathology (T.S.)
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Y. Zhao
cHealthcare Policy and Research (Y.Z.)
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T.H. Schwartz
dNeurological Surgery (T.H.S.), New York-Presbyterian Hospital/Weill Cornell Medical Center, New York, New York.
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C.D. Phillips
aFrom the Departments of Radiology (E.L., C.D.P.)
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    Fig 1.

    Example of an ROI selection. The largest possible elliptic ROI was drawn within the boundaries of the tumor or brain stem on axial images for average signal intensity measurements.

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    Fig 2.

    Axial postcontrast T1 images of pathologically proved chordomas, demonstrating a range of enhancement characteristics. Patient 1 (A) had an avidly enhancing chordoma, treated with near-gross total resection and proton beam radiation therapy. Twenty-four-month follow-up (not shown) demonstrated significant progression of tumor, treated with re-resection, but with further progression of tumor 10 months later. Patient 2 (B) had a heterogeneously enhancing chordoma, treated with near-gross total resection and proton beam radiation therapy. There was progression of the tumor at 29-month follow-up (not shown). Patient 3 (C) had a nonenhancing chordoma, treated with near-gross total resection and proton beam radiation therapy. As of 52-month follow-up (not shown), there has been no evidence of tumor progression.

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Prognostic Implications of Gadolinium Enhancement of Skull Base Chordomas
E. Lin, T. Scognamiglio, Y. Zhao, T.H. Schwartz, C.D. Phillips
American Journal of Neuroradiology Jun 2018, DOI: 10.3174/ajnr.A5714
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E. Lin, T. Scognamiglio, Y. Zhao, T.H. Schwartz, C.D. Phillips
Prognostic Implications of Gadolinium Enhancement of Skull Base Chordomas
American Journal of Neuroradiology Jun 2018, DOI: 10.3174/ajnr.A5714

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