Article Figures & Data
Figures
- FIGURE.
Representative examples of patients with different thrombus-changing patterns. A–D, Examples of thrombus extension. A, Arterial peak phase of 4D-CTA shows the collateral flow at baseline, with an arrival time delay of 6.8 seconds. Thrombus length was measured on tMIP of 4D-CTA (B) and a merged image of dGE-T1 and TOF-MRA (C), which was 4.0 mm at baseline and 18.8 mm at 24 hours. D, Magnitude image at 24 hours also shows the thrombus. E–H, Examples of thrombus without change. E, The arterial peak phase of 4D-CTA shows the collateral flow at baseline with an ATD of 3.3 seconds. Thrombus length was measured on tMIP of 4D-CTA (F) and the merged image of dGE-T1 and TOF-MRA (G), which was 11.2 mm at baseline and 10.9 mm at 24 hours. H, Magnitude image at 24 hours also shows the thrombus.
Tables
Thrombus Shortening (n = 14) Thrombus without Change (n = 19) Thrombus Extension (n = 18) P Value Age (yr) (mean) 62.79 ± 14.74 67.53 ± 13.47 70.44 ± 11.63 .275 Women (No.) (%) 4 (28.6) 7 (36.8) 9 (50) .480 Comorbid conditions Atrial fibrillation (No.) (%) 7 (50) 9 (47.4) 10 (55.6) .938 Hypertension (No.) (%) 10 (71.4) 15 (78.9) 16 (88.9) .502 Diabetes (No.) (%) 1 (7.1) 2 (10.5) 5 (27.8) .245 Hyperlipidemia (No.) (%) 10 (71.4) 10 (52.6) 8 (44.4) .316 Smoking (No.) (%) 7 (50) 10 (52.6) 6 (33.3) .461 Clinical variables NIHSS score (range) 6.5 (4.5–11.75) 11 (7–16) 16 (13–18) <.001 Onset to imaging (mean) (min) 201.43 ± 98.09 233.58 ± 139.42 175.28 ± 67.20 .263 Previous antiplatelet use (No.) (%) 2 (14.3) 4 (21.1) 1 (6.6) .406 Platelets (109/L) (mean) 189.50 ± 84.43 200.89 ± 98.60 179.94 ± 42.89 .723 INR (mean) 1.07 ± 0.14 1.02 ± 0.07 1.01 ± 0.08 .229 Baseline thrombus length (range) (mm) 12.99 (6.93–18.74) 8.0 (3.3–11.10) 13.31 (6.35–17.59) .116 Baseline ATD (range) (sec) 3.24 (1.71–5.42) 2.77 (0.90–4.48) 7.24 (3.52–9.18) .001 Peak score of collaterals (range) 3 (1–3) 3 (1–3) 1 (0–2) .001 tMIP score of collaterals (range) 3 (1–3) 3 (2–3) 2 (1–3) .176 Poor outcome (No.) (%) 7 (50) 16 (84.2) 18 (100) .001 Note:—INR indicates international normalized ratio.
- Table 2:
Logistic regression for prediction of thrombus extension and shortening, including ATD in the model
OR 95% CI P Value For thrombus extension (set without change as reference) NIHSS score 1.195 0.978–1.460 .081 Baseline thrombus length (mm) 0.981 0.853–1.129 .790 Baseline ATD (sec) 1.499 1.053–2.135 .025 For thrombus shortening (set without change as reference) NIHSS score 0.768 0.614–0.961 .021 Baseline thrombus length (mm) 1.193 1.021–1.394 .026 Baseline ATD (sec) 0.955 0.647–1.410 .818 - Table 3:
Logistic regression for prediction of thrombus extension and shortening, including baseline peak score of collaterals in the model
OR 95% CI P Value For thrombus extension (set without change as reference) NIHSS score 1.146 0.935–1.404 .189 Baseline thrombus length (mm) 1.042 0.915–1.186 .537 Baseline peak score of collaterals 0.456 0.211–0.984 .045 For thrombus shortening (set without change as reference) NIHSS score 0.742 0.580–0.950 .018 Baseline thrombus length (mm) 1.220 1.037–1.435 .016 Baseline peak score of collaterals 0.899 0.316–2.557 .841 - Table 4:
Logistic regression for prediction of thrombus extension and shortening, including baseline tMIP score of collaterals in the model
OR 95% CI P Value For thrombus extension (set without change as reference) NIHSS score 1.162 0.965–1.399 .113 Baseline thrombus length (mm) 1.076 0.953–1.216 .238 Baseline tMIP score of collaterals 0.759 0.341–1.690 .499 For thrombus shortening (set without change as reference) NIHSS score 0.719 0.563–0.917 .008 Baseline thrombus length (mm) 1.210 1.039–1.409 .014 Baseline tMIP score of collaterals 0.571 0.212–1.536 .267
