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Research ArticlePediatric Neuroimaging

Does the Addition of a “Black Bone” Sequence to a Fast Multisequence Trauma MR Protocol Allow MRI to Replace CT after Traumatic Brain Injury in Children?

M.H.G. Dremmen, M.W. Wagner, T. Bosemani, A. Tekes, D. Agostino, E. Day, B.P. Soares and T.A.G.M. Huisman
American Journal of Neuroradiology September 2017, DOI: https://doi.org/10.3174/ajnr.A5405
M.H.G. Dremmen
aFrom the Section of Pediatric Neuroradiology (M.H.G.D., M.W.W., T.B., A.T., D.A., E.D., B.P.S., T.A.G.M.H.), Division of Pediatric Radiology and Pediatric Neuroradiology, Department of Radiology and Radiological Science, Johns Hopkins Hospital, Baltimore, Maryland
bDivision of Pediatric Radiology (M.H.G.D.), Department of Radiology, Erasmus University Medical Center Rotterdam, Rotterdam, the Netherlands
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M.W. Wagner
aFrom the Section of Pediatric Neuroradiology (M.H.G.D., M.W.W., T.B., A.T., D.A., E.D., B.P.S., T.A.G.M.H.), Division of Pediatric Radiology and Pediatric Neuroradiology, Department of Radiology and Radiological Science, Johns Hopkins Hospital, Baltimore, Maryland
cInstitute of Diagnostic and Interventional Radiology (M.W.W.), University Hospital Zurich, Zurich, Switzerland.
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T. Bosemani
aFrom the Section of Pediatric Neuroradiology (M.H.G.D., M.W.W., T.B., A.T., D.A., E.D., B.P.S., T.A.G.M.H.), Division of Pediatric Radiology and Pediatric Neuroradiology, Department of Radiology and Radiological Science, Johns Hopkins Hospital, Baltimore, Maryland
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A. Tekes
aFrom the Section of Pediatric Neuroradiology (M.H.G.D., M.W.W., T.B., A.T., D.A., E.D., B.P.S., T.A.G.M.H.), Division of Pediatric Radiology and Pediatric Neuroradiology, Department of Radiology and Radiological Science, Johns Hopkins Hospital, Baltimore, Maryland
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D. Agostino
aFrom the Section of Pediatric Neuroradiology (M.H.G.D., M.W.W., T.B., A.T., D.A., E.D., B.P.S., T.A.G.M.H.), Division of Pediatric Radiology and Pediatric Neuroradiology, Department of Radiology and Radiological Science, Johns Hopkins Hospital, Baltimore, Maryland
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E. Day
aFrom the Section of Pediatric Neuroradiology (M.H.G.D., M.W.W., T.B., A.T., D.A., E.D., B.P.S., T.A.G.M.H.), Division of Pediatric Radiology and Pediatric Neuroradiology, Department of Radiology and Radiological Science, Johns Hopkins Hospital, Baltimore, Maryland
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B.P. Soares
aFrom the Section of Pediatric Neuroradiology (M.H.G.D., M.W.W., T.B., A.T., D.A., E.D., B.P.S., T.A.G.M.H.), Division of Pediatric Radiology and Pediatric Neuroradiology, Department of Radiology and Radiological Science, Johns Hopkins Hospital, Baltimore, Maryland
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T.A.G.M. Huisman
aFrom the Section of Pediatric Neuroradiology (M.H.G.D., M.W.W., T.B., A.T., D.A., E.D., B.P.S., T.A.G.M.H.), Division of Pediatric Radiology and Pediatric Neuroradiology, Department of Radiology and Radiological Science, Johns Hopkins Hospital, Baltimore, Maryland
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    Fig 1.

    A, Axial CT image shows a nondisplaced linear fracture of the right parietal bone (arrow) with extracranial soft-tissue swelling. Black bone (B) and inverted black bone (C) MR images reveal equivalent visualization of the right parietal fracture (arrows), as well as overlying soft-tissue swelling.

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    Fig 2.

    A, Axial CT image shows 2 small nondisplaced linear fractures of the mastoid (arrows). On black bone (B) and inverted black bone (C) MR images, these fractures are barely visible (arrows).

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    Fig 3.

    A, Axial CT image does not show intracranial hemorrhage. A matching axial T2-weighted MR image (B), axial trace of diffusion (C), ADC map (D), minimal intensity projection–SWI (E), and inverted black bone MR image (F) reveal areas of T2-hyperintense signal and restricted diffusion within the temporal white matter (arrows in B–D), areas of restricted diffusion within the right frontal lobe and splenium of the corpus callosum (arrows in C and D), and foci of hypointense SWI signal within the right frontal white matter (arrows in E), suggestive of intracranial hemorrhages and diffuse axonal injury not seen on axial CT.

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    Table 1:

    Number and types of skull fractures and intracranial hemorrhages detected on axial 2D head CT and brain MRI including the black bone sequence in 28 children with head trauma

    No. of PatientsPercentage of Patients
    Skull fractures1243%
        Linear1139%
        Depressed14%
    Intracranial hemorrhage2279%
        Isolated subdural414%
        Isolated epidural311%
        Isolated intraparenchymal311%
        Mixed1243%
    • View popup
    Table 2:

    Diagnostic accuracy of axial 2D head CT compared with brain MRI including the black bone sequence for the detection of skull fractures, intracranial hemorrhages, and skull fractures and/or intracranial hemorrhages combined in 28 children with head trauma

    Skull FracturesIntracranial HemorrhagesSkull Fracture and/or Intracranial Hemorrhages
    MRI + BB (Compared with CT)Axial CT (Compared with MRI)Axial CTMRI + BB
    Sensitivity66.7%72.7%81.8%100%
    Specificity87.5%83.3%83.3%100%
    PPV80.0%94.1%94.7%100%
    NPV77.8%45.5%55.6%100%
    • Note:—BB indicates black bone MRI sequence.

    • View popup
    Table 3:

    Differences in diagnostic accuracy of brain MRI including the black bone sequence for the detection of skull fractures in 28 children with head trauma, depending on the age of the child and MR imaging field strength

    Age at MRIMRI Field Strength
    Younger Than 2 yr (n = 14)2 yr and Older (n = 14)1.5T (n = 12)3T (n = 16)
    Sensitivity75.0%50.0%83.3%50.0%
    Specificity66.7%100%83.3%90.0%
    PPV75.0%100%83.3%75.0%
    NPV66.7%83.3%83.3%75.0%
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Cite this article
M.H.G. Dremmen, M.W. Wagner, T. Bosemani, A. Tekes, D. Agostino, E. Day, B.P. Soares, T.A.G.M. Huisman
Does the Addition of a “Black Bone” Sequence to a Fast Multisequence Trauma MR Protocol Allow MRI to Replace CT after Traumatic Brain Injury in Children?
American Journal of Neuroradiology Sep 2017, DOI: 10.3174/ajnr.A5405

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Does the Addition of a “Black Bone” Sequence to a Fast Multisequence Trauma MR Protocol Allow MRI to Replace CT after Traumatic Brain Injury in Children?
M.H.G. Dremmen, M.W. Wagner, T. Bosemani, A. Tekes, D. Agostino, E. Day, B.P. Soares, T.A.G.M. Huisman
American Journal of Neuroradiology Sep 2017, DOI: 10.3174/ajnr.A5405
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