Case of the Week

Section Editors: Matylda Machnowska1 and Anvita Pauranik2
1University of Toronto, Toronto, Ontario, Canada
2BC Children's Hospital, University of British Columbia, Vancouver, British Columbia, Canada

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November 5, 2012

(Intraosseous) Anterior Skull Base Meningioma

  • Meningiomas are tumors derived from arachnoid cells. Typically meningiomas are therefore dural-based tumors.
  • Extradural meningiomas are rare and account for only 2% of all meningiomas. Of these, 14% are of the intraosseous variety. These tumors are thought to arise from trapped arachnoid cells, and, therefore, are most commonly seen at the sites of cranial sutures or fractures.
  • Key Diagnostic Features: Radiologic findings are variable. Such tumors can be osteolytic, osteolytic-blastic, or osteoblastic. The more common osteoblastic form demonstrates thickened calvarium, widening of the diploic space, sclerosis, occasional radial spiculations, and associated hyperostosis.
  • DDx: esthesioneuroblastoma, sinonasal undifferentiated tumor, osteoma, metastasis, hemangioma, fibrous dysplasia
  • Rx: surgical excision
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