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AJNR Awards, New Junior Editors, and more. Read the latest AJNR updates

Case of the Week

Section Editors: Matylda Machnowska1 and Anvita Pauranik2
1University of Toronto, Toronto, Ontario, Canada
2BC Children's Hospital, University of British Columbia, Vancouver, British Columbia, Canada

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Submit a Case Previous Cases ASPNR Pediatric Cases

June 23, 2014
  • Description
  • Legends
  • Diagnosis
  • Brain Teaser
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Giant Cavernous Angioma

  • Giant cavernomas are benign vascular malformations.
  • When small, diagnosis is usually straightforward. Larger lesions result in complex-looking lesions and can be more difficult to diagnose.
  • Clinical Presentation: Nonspecific. Headache is a common complaint.
  • Key Imaging Features:  Small lesions: "Popcorn" appearance. Larger lesions: Complex-appearing, with a heterogeneous appearance on T1WI and T2WI, and with foci of susceptibility within. A complete hemosiderin rim can be seen. Alternatively, in a more acute setting, a fluid-fluid level is seen, suggestive of recent hemorrhage. Heterogeneous enhancement is seen following contrast administration. Presence of an associated developmental venous anomaly, best seen on susceptibility-weighted imaging or contrast-enhanced MPRAGE sequence, helps in making the diagnosis.
  • DDx: Primary neuronal mixed neural-glial tumor
  • Rx: Conservative if small. Larger lesions may require surgical excision.

Suggested Reading

Kan P, Tubay M, Osborn A, et al. Radiographic features of tumefactive giant cavernous angiomas. Acta Neurochir (Wien) 2008;150:49–55, 10.1007/s00701-007-1455-z

Gelal F, Feran H, Rezanko T, et al. Giant cavernous angioma of the temporal lobe: a case report and review of the literature. Acta Radiol 2005;46:310–13, 10.1080/02841850510012698

Current Issue

American Journal of Neuroradiology: 46 (6)
American Journal of Neuroradiology
Vol. 46, Issue 6
1 Jun 2025
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Print ISSN: 0195-6108 Online ISSN: 1936-959X

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