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AJNR Awards, New Junior Editors, and more. Read the latest AJNR updates

Case of the Week

Section Editors: Matylda Machnowska1 and Anvita Pauranik2
1University of Toronto, Toronto, Ontario, Canada
2BC Children's Hospital, University of British Columbia, Vancouver, British Columbia, Canada

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February 27, 2012
  • Description
  • Legends
  • Diagnosis
  • Brain Teaser
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Direct Carotid Cavernous Fistula

  • Carotid-cavernous fistula (CCF) represents an abnormal communication between the internal carotid artery and the cavernous venous sinus.
  • CCFs are further classified as direct (ICA-cavernous sinus) or indirect (dural arteries-cavernous sinus) types. CCFs are either traumatic or spontaneous in etiology.
  • Most patients present with exophthalmos, orbital edema, and occasional ecchymosis. A vascular bruit can often be elicited over the involved orbit.
  • Key Diagnostic Features: Proptosis, stranding of retrobulbar fat, prominent superior ophthalmic vein, and enlargement of the extra-occular muscles. Fullness in the region of the cavernous sinuses is often seen. An aneurysm is occasionally seen in the region of the left cavernous sinus. A CCF can be demonstrated on CT/MR or conventional DSA.
  • DDx: Superior ophthalmic vein varix, orbital arterio-venous malformation
  • Rx: Occlusion

Suggested Reading

Smoker WRK, Gentry LR, Yee NK, et al. Vascular Lesions of the Orbit: More than Meets the Eye. RadioGraphics 2008;28:185-05. doi: 10.1148/rg.281075040

Chen CCC, Chang PCT, Shy CG, et al. CT Angiography and MR Angiography in the Evaluation of Carotid Cavernous Sinus Fistula Prior to Embolization: A Comparison of Techniques. AJNR Am J Neuroradiol 2005;26:2349-56.

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American Journal of Neuroradiology: 46 (6)
American Journal of Neuroradiology
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