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AJNR Awards, New Junior Editors, and more. Read the latest AJNR updates

Case of the Month

Section Editor: Nicholas Stence, MD
Children's Hospital Colorado, Aurora, CO

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October 2013
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Next Case of the Month coming November 5 . . .

Cavernous Malformation with DVA

  • Cavernous malformations, aka cavernomas, are compact, vascular malformations composed of endothelial-lined sinusoidal spaces containing slow-flowing blood.
  • Often intra-axial, rarely extra-axial. Uncommonly in the spine.
  • Clinical Presentation: Oftentimes detected incidentally. When ruptured, presents with headache and, occasionally, focal neurological deficit.
  • Key Diagnostic Features: "Popcorn-like" lesion demonstrating a hyperintense center surrounded by a hemosiderin/ferritin rim is the classic MR appearance. A fluid-fluid level is seen in the setting of acute hemorrhage. An associated developmental venous anomaly is often seen adjacent to the cavernous malformation and, in fact, sometimes, like in the current case, helps establish the diagnosis.
  • DDx: Tumor, aneurysm, arteriovenous malformation, infection
  • Rx: Observation, surgical excision

Suggested Reading

Abe T, Singer RJ, Marks MP, et al. Coexistence of occult vascular malformations and developmental venous anomalies in the central nervous system: MR evaluation. AJNR Am J Neuroradiol 1998;19:51–57

Biondi A, Clemenceau S, Dormont D, et al. Intracranial extra-axial cavernous (hem)angiomas: Tumors or vascular malformations ? Report of five cases and review of the literature. J Neuroradiol 2002;29:91–104

Current Issue

American Journal of Neuroradiology: 46 (5)
American Journal of Neuroradiology
Vol. 46, Issue 5
1 May 2025
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Print ISSN: 0195-6108 Online ISSN: 1936-959X

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