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Research ArticleNeurovascular/Stroke Imaging
Open Access

CT-Based Intrathrombus and Perithrombus Radiomics for Prediction of Prognosis after Endovascular Thrombectomy: A Retrospective Study across 2 Centers

Minda Li, Jingxuan Jiang, Hongmei Gu, Su Hu, Jingli Wang and Chunhong Hu
American Journal of Neuroradiology April 2025, 46 (4) 681-688; DOI: https://doi.org/10.3174/ajnr.A8522
Minda Li
aFrom the Department of Radiology (M.L., S.H., C.H.), The First Affiliated Hospital of Soochow University, Suzhou, China
bDepartment of Radiology (M.L., J.J., H.G.), Affiliated Hospital of Nantong University, Nantong, China
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Jingxuan Jiang
bDepartment of Radiology (M.L., J.J., H.G.), Affiliated Hospital of Nantong University, Nantong, China
cInstitute of Diagnostic and Interventional Radiology (J.J.), Shanghai Sixth People’s Hospital Affiliated to Shanghai Jiao Tong University School of Medicine, Shanghai, China
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Hongmei Gu
bDepartment of Radiology (M.L., J.J., H.G.), Affiliated Hospital of Nantong University, Nantong, China
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Su Hu
aFrom the Department of Radiology (M.L., S.H., C.H.), The First Affiliated Hospital of Soochow University, Suzhou, China
dInstitute of Medical Imaging (H.S., C.H.), Soochow University, Suzhou, China
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Jingli Wang
eStroke Center (J.W.), Affiliated Hospital of Nantong University, Nantong, China.
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Chunhong Hu
aFrom the Department of Radiology (M.L., S.H., C.H.), The First Affiliated Hospital of Soochow University, Suzhou, China
dInstitute of Medical Imaging (H.S., C.H.), Soochow University, Suzhou, China
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References

  1. 1.↵
    GBD 2016 Neurology Collaborators. Global, regional, and national burden of stroke, 1990-2016: a systematic analysis for the Global Burden of Disease Study 2016. Lancet Neurol 2019;18:439–58 doi:10.1016/S1474-4422(19)30034-1 pmid:30879893
    CrossRefPubMed
  2. 2.↵
    1. Sarraj A,
    2. Hassan AE,
    3. Abraham MG, et al
    ; SELECT2 Investigators. Trial of endovascular thrombectomy for large ischemic strokes. N Engl J Med 2023;388:1259–71 doi:10.1056/NEJMoa2214403 pmid:36762865
    CrossRefPubMed
  3. 3.↵
    1. Yoshimura S,
    2. Sakai N,
    3. Yamagami H, et al
    . Endovascular therapy for acute stroke with a large ischemic region. N Engl J Med 2022;386:1303–13 doi:10.1056/NEJMoa2118191 pmid:35138767
    CrossRefPubMed
  4. 4.↵
    1. Zhang X,
    2. Xie Y,
    3. Wang H, et al
    . Symptomatic intracranial hemorrhage after mechanical thrombectomy in Chinese ischemic stroke patients: the ASIAN score. Stroke 2020;51:2690–96 doi:10.1161/STROKEAHA.120.030173 pmid:32811387
    CrossRefPubMed
  5. 5.↵
    1. Zi W,
    2. Qiu Z,
    3. Li F, et al
    ; DEVT Trial Investigators. Effect of endovascular treatment alone vs intravenous alteplase plus endovascular treatment on functional independence in patients with acute ischemic stroke: the DEVT randomized clinical trial. JAMA 2021;325:234–43 doi:10.1001/jama.2020.23523 pmid:33464335
    CrossRefPubMed
  6. 6.↵
    1. Harker P,
    2. Aziz YN,
    3. Vranic J, et al
    . Asymptomatic intracerebral hemorrhage following endovascular stroke therapy is not benign: a systematic review and meta-analysis. J Am Heart Assoc 2024;13:e031749 doi:10.1161/JAHA.123.031749 pmid:38348800
    CrossRefPubMed
  7. 7.↵
    1. Huang X,
    2. Yang Q,
    3. Shi X, et al
    . Predictors of malignant brain edema after mechanical thrombectomy for acute ischemic stroke. J Neurointerv Surg 2019;11:994–98 doi:10.1136/neurintsurg-2018-014650 pmid:30798266
    Abstract/FREE Full Text
  8. 8.↵
    1. Thorén M,
    2. Dixit A,
    3. Escudero-Martínez I, et al
    . Effect of recanalization on cerebral edema in ischemic stroke treated with thrombolysis and/or endovascular therapy. Stroke 2020;51:216–23 doi:10.1161/STROKEAHA.119.026692 pmid:31818228
    CrossRefPubMed
  9. 9.↵
    1. Merlino G,
    2. Tereshko Y,
    3. Pez S, et al
    . Hyperdense middle cerebral artery sign predicts favorable outcome in patients undergoing mechanical thrombectomy. J Thromb Thrombolysis 2023;55:312–21 doi:10.1007/s11239-022-02731-4 pmid:36434302
    CrossRefPubMed
  10. 10.↵
    1. Lu ZJ,
    2. Lai JX,
    3. Huang JR, et al
    . Predictive value of intracranial high-density areas in neurological function. World J Psychiatry 2024;14:1080–86 doi:10.5498/wjp.v14.i7.1080 pmid:39050205
    CrossRefPubMed
  11. 11.↵
    1. Beyeler M,
    2. Pohle F,
    3. Weber L, et al
    . Long-term effect of mechanical thrombectomy in stroke patients according to advanced imaging characteristics. Clin Neuroradiol 2024;34:105–14 doi:10.1007/s00062-023-01337-4 pmid:37642685
    CrossRefPubMed
  12. 12.↵
    1. Olivot JM,
    2. Albucher JF,
    3. Guenego A, et al
    ; FRAME Investigator. Mismatch profile influences outcome after mechanical thrombectomy. Stroke 2021;52:232–40 doi:10.1161/STROKEAHA.120.031929 pmid:33349010
    CrossRefPubMed
  13. 13.↵
    1. Xiong X,
    2. Wang J,
    3. Ke J, et al
    . Radiomics-based intracranial thrombus features on preoperative noncontrast CT predicts successful recanalization of mechanical thrombectomy in acute ischemic stroke. Quant Imaging Med Surg 2023;13:682–94 doi:10.21037/qims-22-599 pmid:36819277
    CrossRefPubMed
  14. 14.↵
    1. Wang C,
    2. Li T,
    3. Jia Z, et al
    . Radiomics features on computed tomography reflect thrombus histological age prior to endovascular treatment of acute ischemic stroke. J Stroke Cerebrovasc Dis 2023;32:107358 doi:10.1016/j.jstrokecerebrovasdis.2023.107358 pmid:37716105
    CrossRefPubMed
  15. 15.↵
    1. Jiang J,
    2. Wei J,
    3. Zhu Y, et al
    . Clot-based radiomics model for cardioembolic stroke prediction with CT imaging before recanalization: a multicenter study. Eur Radiol 2023;33:970–80 doi:10.1007/s00330-022-09116-4 pmid:36066731
    CrossRefPubMed
  16. 16.↵
    1. Wang C,
    2. Hang Y,
    3. Cao Y, et al
    . A nomogram for predicting thrombus composition in stroke patients with large vessel occlusion: combination of thrombus density and perviousness with clinical features. Neuroradiology 2023;65:371–80 doi:10.1007/s00234-022-03046-0 pmid:36064806
    CrossRefPubMed
  17. 17.↵
    1. Qiu W,
    2. Kuang H,
    3. Nair J, et al
    . Radiomics-based intracranial thrombus features on CT and CTA predict recanalization with intravenous alteplase in patients with acute ischemic stroke. AJNR Am J Neuroradiol 2019;40:39–44 doi:10.3174/ajnr.A5918 pmid:30573458
    Abstract/FREE Full Text
  18. 18.↵
    1. Cheng Y,
    2. Wan S,
    3. Wu W, et al
    . Computed tomography angiography-based thrombus radiomics for predicting the time since stroke onset. Acad Radiol 2023;30:2469–76 doi:10.1016/j.acra.2022.12.032 pmid:36697269
    CrossRefPubMed
  19. 19.↵
    1. Alawieh A,
    2. Vargas J,
    3. Fargen KM, et al
    . Impact of procedure time on outcomes of thrombectomy for stroke. J Am Coll Cardiol 2019;73:879–90 doi:10.1016/j.jacc.2018.11.052 pmid:30819354
    FREE Full Text
  20. 20.↵
    1. Bourcier R,
    2. Saleme S,
    3. Labreuche J, et al
    ; ASTER Trial Investigators. More than three passes of stent retriever is an independent predictor of parenchymal hematoma in acute ischemic stroke. J Neurointerv Surg 2019;11:625–29 doi:10.1136/neurintsurg-2018-014380 pmid:30389897
    Abstract/FREE Full Text
  21. 21.↵
    1. Abbasi M,
    2. Arturo Larco J,
    3. Mereuta MO, et al
    . Diverse thrombus composition in thrombectomy stroke patients with longer time to recanalization. Thromb Res 2022;209:99–104 doi:10.1016/j.thromres.2021.11.018 pmid:34906857
    CrossRefPubMed
  22. 22.↵
    1. Maekawa K,
    2. Shibata M,
    3. Nakajima H, et al
    . Erythrocyte-rich thrombus is associated with reduced number of maneuvers and procedure time in patients with acute ischemic stroke undergoing mechanical thrombectomy. Cerebrovasc Dis Extra 2018;8:39–49 doi:10.1159/000486042 pmid:29402828
    CrossRefPubMed
  23. 23.↵
    1. Funatsu N,
    2. Hayakawa M,
    3. Hashimoto T, et al
    . Vascular wall components in thrombi obtained by acute stroke thrombectomy: clinical significance and related factors. J Neurointerv Surg 2019;11:232–36 doi:10.1136/neurintsurg-2018-014041 pmid:30097483
    Abstract/FREE Full Text
  24. 24.↵
    1. Koge J,
    2. Kato S,
    3. Hashimoto T, et al
    . Vessel wall injury after stent retriever thrombectomy for internal carotid artery occlusion with duplicated middle cerebral artery. World Neurosurg 2019;123:54–58 doi:10.1016/j.wneu.2018.11.223 pmid:30529524
    CrossRefPubMed
  25. 25.↵
    1. Obusez EC,
    2. Hui F,
    3. Hajj-Ali RA, et al
    . High-resolution MRI vessel wall imaging: spatial and temporal patterns of reversible cerebral vasoconstriction syndrome and central nervous system vasculitis. AJNR Am J Neuroradiol 2014;35:1527–32 doi:10.3174/ajnr.A3909 pmid:24722305
    Abstract/FREE Full Text
  26. 26.↵
    1. Zhu C,
    2. Haraldsson H,
    3. Tian B, et al
    . High resolution imaging of the intracranial vessel wall at 3 and 7 T using 3D fast spin echo MRI. MAGMA 2016;29:559–70 doi:10.1007/s10334-016-0531-x pmid:26946509
    CrossRefPubMed
  27. 27.↵
    1. Hom J,
    2. Dankbaar JW,
    3. Soares BP, et al
    . Blood-brain barrier permeability assessed by perfusion CT predicts symptomatic hemorrhagic transformation and malignant edema in acute ischemic stroke. AJNR Am J Neuroradiol 2011;32:41–48 doi:10.3174/ajnr.A2244 pmid:20947643
    Abstract/FREE Full Text
  28. 28.↵
    1. Renú A,
    2. Laredo C,
    3. Lopez-Rueda A, et al
    . Vessel wall enhancement and blood-cerebrospinal fluid barrier disruption after mechanical thrombectomy in acute ischemic stroke. Stroke 2017;48:651–57 doi:10.1161/STROKEAHA.116.015648 pmid:28174330
    Abstract/FREE Full Text
  29. 29.↵
    1. Shi ZS,
    2. Duckwiler GR,
    3. Jahan R, et al
    . Early blood-brain barrier disruption after mechanical thrombectomy in acute ischemic stroke. J Neuroimaging 2018;28:283–88 doi:10.1111/jon.12504 pmid:29484769
    CrossRefPubMed
  30. 30.↵
    1. Gu H,
    2. Zhang X,
    3. di Russo P, et al
    . The current state of radiomics for meningiomas: promises and challenges. Front Oncol 2020;10:567736 doi:10.3389/fonc.2020.567736 pmid:33194649
    CrossRefPubMed
  31. 31.↵
    1. Xie G,
    2. Li T,
    3. Ren Y, et al
    . Radiomics-based infarct features on CT predict hemorrhagic transformation in patients with acute ischemic stroke. Front Neurosci 2022;16:1002717 doi:10.3389/fnins.2022.1002717 pmid:36213752
    CrossRefPubMed
  32. 32.↵
    1. Bisaso KR,
    2. Karungi SA,
    3. Kiragga A, et al
    . A comparative study of logistic regression based machine learning techniques for prediction of early virological suppression in antiretroviral initiating HIV patients. BMC Med Inform Decis Mak 2018;18:77 doi:10.1186/s12911-018-0659-x pmid:30180893
    CrossRefPubMed
  33. 33.↵
    1. van Kranendonk KR,
    2. Treurniet KM,
    3. Boers AM, et al
    ; MR CLEAN Investigators. Clinical and imaging markers associated with hemorrhagic transformation in patients with acute ischemic stroke. Stroke 2019;50:2037–43 doi:10.1161/STROKEAHA.118.024255 pmid:33755497
    CrossRefPubMed
  34. 34.↵
    1. Xu J,
    2. Chen XY,
    3. Wang HY, et al
    . Hemodynamic predictors of early neurological deterioration and clinical outcome after endovascular treatment in large artery occlusion. Heliyon 2024;10:e24746 doi:10.1016/j.heliyon.2024.e24746 pmid:38318012
    CrossRefPubMed
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Minda Li, Jingxuan Jiang, Hongmei Gu, Su Hu, Jingli Wang, Chunhong Hu
CT-Based Intrathrombus and Perithrombus Radiomics for Prediction of Prognosis after Endovascular Thrombectomy: A Retrospective Study across 2 Centers
American Journal of Neuroradiology Apr 2025, 46 (4) 681-688; DOI: 10.3174/ajnr.A8522

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Radiomics Predict Outcomes in Thrombectomy
Minda Li, Jingxuan Jiang, Hongmei Gu, Su Hu, Jingli Wang, Chunhong Hu
American Journal of Neuroradiology Apr 2025, 46 (4) 681-688; DOI: 10.3174/ajnr.A8522
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