Dextromethorphan-Associated Neurotoxicity with Cerebellar Edema Syndrome in Young Children: Neuroimaging Features

References

1. 1.↵
   1. Kim DD,
   2. Prasad AN

   . Clinical and radiologic features of pediatric opioid use‐associated neurotoxicity with cerebellar edema (POUNCE) syndrome. Neurology 2020;94:710–12 doi:10.1212/WNL.0000000000009293 pmid:32198237

   CrossRefPubMed
2. 2.↵
   1. Duran D,
   2. Messina RD,
   3. Beslow LA, et al

   . Malignant cerebellar edema subsequent to accidental prescription opioid intoxication in children. Front Neurol 2017;8:362 doi:10.3389/fneur.2017.00362 pmid:28790973

   CrossRefPubMed
3. 3.↵
   1. Wheaton T,
   2. Toll BJ,
   3. Breznak K, et al

   . Opioid-induced toxic leukoencephalopathy: a case report and review of the literature. Heliyon 2019;5:e03005 doi:10.1016/j.heliyon.2019.e03005 pmid:31879710

   CrossRefPubMed
4. 4.↵
   1. Chen CH,
   2. Mullen AJ,
   3. Hofstede D, et al

   . Malignant cerebellar edema in three-year-old girl following accidental opioid ingestion and fentanyl administration. Neuroradiol J 2019;32:386–91 doi:10.1177/1971400919863713 pmid:31328634

   CrossRefPubMed
5. 5.↵
   1. Haut LN,
   2. Radhakrishnan R,
   3. Lutfi R, et al

   . Acute cytotoxic cerebellar edema subsequent to fentanyl patch intoxication in an infant. Case Rep Crit Care 2021;2021:9449565 doi:10.1155/2021/9449565 pmid:34540294

   CrossRefPubMed
6. 6.↵
   1. Reisner A,
   2. Hayes LL,
   3. Holland CM, et al

   . Opioid overdose in a child: case report and discussion with emphasis on neurosurgical implications. J Neurosurg Pediatr 2015;16:752–57 doi:10.3171/2015.4.PEDS14667 pmid:26339960

   CrossRefPubMed
7. 7.↵
   1. Nanan R,
   2. Von Stockhausen HB,
   3. Petersen B, et al

   . Unusual pattern of leukoencephalopathy after morphine sulphate intoxication. Neuroradiology 2000;42:845–48 doi:10.1007/s002340000442 pmid:11151694

   CrossRefPubMedWeb of Science
8. 8.↵
   1. Bellot B,
   2. Michel F,
   3. Thomachot L, et al

   . Acute leukoencephalopathy after buprenorphine intoxication in a 2-year-old child. Eur J Paediatr Neurol 2011;15:368–71 doi:10.1016/j.ejpn.2011.03.002 pmid:21450498

   CrossRefPubMed
9. 9.↵
   1. Haghighi-Morad M,
   2. Naseri Z,
   3. Jamshidi N, et al

   . Methadone-induced encephalopathy: a case series and literature review. BMC Med Imaging 2020;20:6–9 doi:10.1186/s12880-020-0410-9

   CrossRefPubMed
10. 10.↵
    1. Tiong SC,
    2. Chieng JS,
    3. Khoo HW, et al

    . Methadone-induced toxic encephalopathy in pediatric patients: two case reports. J Radiol Case Rep 2019;13:1–9 doi:10.3941/jrcr.v13i5.3658 pmid:31558953

    CrossRefPubMed
11. 11.↵
    1. Mills F,
    2. MacLennan SC,
    3. Devile CJ, et al

    . Severe cerebellitis following methadone poisoning. Pediatr Radiol 2008;38:227–29 doi:10.1007/s00247-007-0635-6 pmid:17952429

    CrossRefPubMed
12. 12.↵
    1. Rando J,
    2. Szari S,
    3. Kumar G, et al

    . Methadone overdose causing acute cerebellitis and multi-organ damage. Am J Emerg Med 2015;34:343.e1–3 doi:10.1016/j.ajem.2015.06.032 pmid:26164407

    CrossRefPubMed
13. 13.↵
    1. Journey JD,
    2. Agrawal S,
    3. Stern E

    . Dextromethorphan toxicity. StatPearl. Treasure Island, Florida; StatPearls Publishing; 2024. https://www.ncbi.nlm.nih.gov/books/NBK538502. Accessed August 2, 2024
14. 14.↵
    1. Rosenbaum C,
    2. Boyer EW

    . Dextromethorphan misuse and poisoning: clinical features and diagnosis. UpToDate. https://www.uptodate.com/contents/dextromethorphan-misuse-and-poisoning-clinical-features-and-diagnosis. Accessed December 28, 2023
15. 15.↵
    Medline Plus. Dextromethorphan. 2019. https://medlineplus.gov/druginfo/meds/a682492.html. Accessed August 2, 2024
16. 16.↵
    US Food and Drug Administration. Use caution when giving cough and cold products to kids. https://www.fda.gov/drugs/special-features/use-caution-when-giving-cough-and-cold-products-kids. Accessed August 2, 2024
17. 17.↵
    1. Kumar D,
    2. Shinde V,
    3. Khuraijam S, et al

    . Two cases of dextromethorphan overdose reversed by naloxone. Cureus 2023;15:e34501 doi:10.7759/cureus.34501 pmid:36874326

    CrossRefPubMed
18. 18.↵
    1. Mallikarjun KS,
    2. Parsons MS,
    3. Nigogosyan Z, et al

    . Neuroimaging findings in CHANTER syndrome: a case series. AJNR Am J Neuroradiol 2022;43:1136–41 doi:10.3174/ajnr.A7569 pmid:35798385

    Abstract/FREE Full Text
19. 19.↵
    1. Jasne AS,
    2. Alsherbini KH,
    3. Smith MS, et al

    . Cerebellar hippocampal and basal nuclei transient edema with restricted diffusion (CHANTER) syndrome. Neurocrit Care 2019;31:288–96 doi:10.1007/s12028-018-00666-4 pmid:30788708

    CrossRefPubMed
20. 20.↵
    1. Atac MF,
    2. Vilanilam GK,
    3. Damalcheruvu PR, et al

    . Cerebellar, hippocampal, and basal nuclei transient edema with restricted diffusion (CHANTER) syndrome in the setting of opioid and phencyclidine use. Radiol Case Rep 2023;18:3496–500 doi:10.1016/j.radcr.2023.07.015 pmid:37554665

    CrossRefPubMed
21. 21.↵
    1. McConnell E,
    2. Bai J,
    3. McConnel E

    . Hippocampal and cerebellar involvement in opioid-associated amnestic syndrome: a unique case report. Cureus 2023;15:e44248 doi:10.7759/cureus.44248 pmid:37772208

    CrossRefPubMed
22. 22.↵
    1. Zagon IS,
    2. Gibo DM,
    3. McLaughlin PJ

    . Adult and developing human cerebella exhibit different profiles of opioid binding sites. Brain Res 1990;523:62–68 doi:10.1016/0006-8993(90)91635-t pmid:2169964

    CrossRefPubMedWeb of Science