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Review ArticlePediatric Neuroimaging

International Consensus Statement on the Radiologic Evaluation of Dysraphic Malformations of the Spine and Spinal Cord

Ankit Balani, Jai Sidpra, Sniya Sudhakar, Asthik Biswas, Özgür Öztekin, Valeria Capra, Martin Catala, Andrew J. Copp, Neetu Kumar, Navroop Johal, M. Zubair Tahir, Dominic Thompson, Dachling Pang, David M. Mirsky, Mai-Lan Ho, Thierry A.G.M. Huisman, Andrea Rossi and Kshitij Mankad
American Journal of Neuroradiology June 2024, 45 (6) 673-680; DOI: https://doi.org/10.3174/ajnr.A8117
Ankit Balani
aFrom the Department of Neuroradiology (A. Balani, J.S., S.S., A. Biswas, K.M.), Great Ormond Street Hospital for Children NHS Foundation Trust, London, UK
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Jai Sidpra
aFrom the Department of Neuroradiology (A. Balani, J.S., S.S., A. Biswas, K.M.), Great Ormond Street Hospital for Children NHS Foundation Trust, London, UK
bDevelopmental Biology and Cancer Section (J.S., A.J.C., K.M.), University College London Great Ormond Street Institute of Child Health, London, UK
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Sniya Sudhakar
aFrom the Department of Neuroradiology (A. Balani, J.S., S.S., A. Biswas, K.M.), Great Ormond Street Hospital for Children NHS Foundation Trust, London, UK
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Asthik Biswas
aFrom the Department of Neuroradiology (A. Balani, J.S., S.S., A. Biswas, K.M.), Great Ormond Street Hospital for Children NHS Foundation Trust, London, UK
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Özgür Öztekin
cDepartment of Neuroradiology (Ö.Ö.), Izmir Bakircay University, Izmir, Turkey
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Valeria Capra
dMedical Genetics Unit (V.C.), IRCCS Istituto Giannina Gaslini, Genoa, Italy
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Martin Catala
eLaboratoire de Biologie du Développement (M.C.), UMR 7622 de Sorbonne Université et du CNRS, ERL 1156 de l’INSERM et Institut de Biologie Paris Seine, Paris, France
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Andrew J. Copp
bDevelopmental Biology and Cancer Section (J.S., A.J.C., K.M.), University College London Great Ormond Street Institute of Child Health, London, UK
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Neetu Kumar
fDepartment of Urology (N.K., N.J.), Great Ormond Street Hospital for Children NHS Foundation Trust, London, UK
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Navroop Johal
fDepartment of Urology (N.K., N.J.), Great Ormond Street Hospital for Children NHS Foundation Trust, London, UK
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M. Zubair Tahir
gDepartment of Neurosurgery (M.Z.T., D.T., D.P.), Great Ormond Street Hospital for Children NHS Foundation Trust, London, UK
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Dominic Thompson
gDepartment of Neurosurgery (M.Z.T., D.T., D.P.), Great Ormond Street Hospital for Children NHS Foundation Trust, London, UK
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Dachling Pang
gDepartment of Neurosurgery (M.Z.T., D.T., D.P.), Great Ormond Street Hospital for Children NHS Foundation Trust, London, UK
hDepartment of Paediatric Neurosurgery (D.P.), University of California, Davis, Davis, California
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David M. Mirsky
iDepartment of Radiology (D.M.M.), Children’s Hospital Colorado, University of Colorado School of Medicine, Aurora, Colorado
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Mai-Lan Ho
jDepartment of Radiology (M.-L.H.), Nationwide Children’s Hospital, Ohio State University, Columbus, Ohio
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Thierry A.G.M. Huisman
kEdward B. Singleton Department of Radiology (T.A.G.M.H.), Texas Children’s Hospital and Baylor College of Medicine, Houston, Texas
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Andrea Rossi
lNeuroradiology Unit (A.R.), IRCCS Istituto Giannina Gaslini, Genoa, Italy
mDepartment of Health Sciences (A.R.), University of Genoa, Genoa, Italy
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Kshitij Mankad
aFrom the Department of Neuroradiology (A. Balani, J.S., S.S., A. Biswas, K.M.), Great Ormond Street Hospital for Children NHS Foundation Trust, London, UK
bDevelopmental Biology and Cancer Section (J.S., A.J.C., K.M.), University College London Great Ormond Street Institute of Child Health, London, UK
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Abstract

SUMMARY: Dysraphic malformations of the spine and spinal cord (DMSSC) represent a spectrum of common congenital anomalies typically (though not exclusively) affecting the lower spinal segments. These may be responsible for varying degrees of neurologic, orthopedic, and urologic morbidity. With advances in neuroimaging, it is now possible to better diagnose and evaluate these disorders both prenatally and postnatally. Neuroimaging, performed at the right time and with technique optimization, is integral in guiding clinical management. However, the terminology used to describe these lesions has become increasingly confusing, and there is a lack of consensus regarding the essential radiologic features and their clinical weighting. This variability in radiologic practice risks unstructured decision making and increases the likelihood of suboptimal, less informed clinical management. In this manuscript, the first of a series of consensus statements, we outline a standardized international consensus statement for the radiologic evaluation of children with suspected DMSSC derived from a critical review of the literature, and the collective clinical experience of a multinational group of experts. We provide recommendations for plain radiography, sonography, CT, and MR imaging in the evaluation of DMSSC with an emphasis on technique of imaging and imaging protocols.

ABBREVIATIONS:

DMSSC
dysraphic malformations of the spine and spinal cord
FS
fat suppression
GRE
gradient-echo
SSFSE
single-shot fast spin-echo
US
ultrasound
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American Journal of Neuroradiology: 45 (6)
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Cite this article
Ankit Balani, Jai Sidpra, Sniya Sudhakar, Asthik Biswas, Özgür Öztekin, Valeria Capra, Martin Catala, Andrew J. Copp, Neetu Kumar, Navroop Johal, M. Zubair Tahir, Dominic Thompson, Dachling Pang, David M. Mirsky, Mai-Lan Ho, Thierry A.G.M. Huisman, Andrea Rossi, Kshitij Mankad
International Consensus Statement on the Radiologic Evaluation of Dysraphic Malformations of the Spine and Spinal Cord
American Journal of Neuroradiology Jun 2024, 45 (6) 673-680; DOI: 10.3174/ajnr.A8117

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International Consensus on Dysraphic Malformations
Ankit Balani, Jai Sidpra, Sniya Sudhakar, Asthik Biswas, Özgür Öztekin, Valeria Capra, Martin Catala, Andrew J. Copp, Neetu Kumar, Navroop Johal, M. Zubair Tahir, Dominic Thompson, Dachling Pang, David M. Mirsky, Mai-Lan Ho, Thierry A.G.M. Huisman, Andrea Rossi, Kshitij Mankad
American Journal of Neuroradiology Jun 2024, 45 (6) 673-680; DOI: 10.3174/ajnr.A8117
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