Skip to main content
Advertisement

Main menu

  • Home
  • Content
    • Current Issue
    • Accepted Manuscripts
    • Article Preview
    • Past Issue Archive
    • Video Articles
    • AJNR Case Collection
    • Case of the Week Archive
    • Case of the Month Archive
    • Classic Case Archive
  • Special Collections
    • AJNR Awards
    • Low-Field MRI
    • Alzheimer Disease
    • ASNR Foundation Special Collection
    • Photon-Counting CT
    • View All
  • Multimedia
    • AJNR Podcasts
    • AJNR SCANtastic
    • Trainee Corner
    • MRI Safety Corner
    • Imaging Protocols
  • For Authors
    • Submit a Manuscript
    • Submit a Video Article
    • Submit an eLetter to the Editor/Response
    • Manuscript Submission Guidelines
    • Statistical Tips
    • Fast Publishing of Accepted Manuscripts
    • Graphical Abstract Preparation
    • Imaging Protocol Submission
    • Author Policies
  • About Us
    • About AJNR
    • Editorial Board
    • Editorial Board Alumni
  • More
    • Become a Reviewer/Academy of Reviewers
    • Subscribers
    • Permissions
    • Alerts
    • Feedback
    • Advertisers
    • ASNR Home

User menu

  • Alerts
  • Log in

Search

  • Advanced search
American Journal of Neuroradiology
American Journal of Neuroradiology

American Journal of Neuroradiology

ASHNR American Society of Functional Neuroradiology ASHNR American Society of Pediatric Neuroradiology ASSR
  • Alerts
  • Log in

Advanced Search

  • Home
  • Content
    • Current Issue
    • Accepted Manuscripts
    • Article Preview
    • Past Issue Archive
    • Video Articles
    • AJNR Case Collection
    • Case of the Week Archive
    • Case of the Month Archive
    • Classic Case Archive
  • Special Collections
    • AJNR Awards
    • Low-Field MRI
    • Alzheimer Disease
    • ASNR Foundation Special Collection
    • Photon-Counting CT
    • View All
  • Multimedia
    • AJNR Podcasts
    • AJNR SCANtastic
    • Trainee Corner
    • MRI Safety Corner
    • Imaging Protocols
  • For Authors
    • Submit a Manuscript
    • Submit a Video Article
    • Submit an eLetter to the Editor/Response
    • Manuscript Submission Guidelines
    • Statistical Tips
    • Fast Publishing of Accepted Manuscripts
    • Graphical Abstract Preparation
    • Imaging Protocol Submission
    • Author Policies
  • About Us
    • About AJNR
    • Editorial Board
    • Editorial Board Alumni
  • More
    • Become a Reviewer/Academy of Reviewers
    • Subscribers
    • Permissions
    • Alerts
    • Feedback
    • Advertisers
    • ASNR Home
  • Follow AJNR on Twitter
  • Visit AJNR on Facebook
  • Follow AJNR on Instagram
  • Join AJNR on LinkedIn
  • RSS Feeds

AJNR Awards, New Junior Editors, and more. Read the latest AJNR updates

Research ArticleFunctional

Perifocal Edema in Patients with Meningioma is Associated with Impaired Whole-Brain Connectivity as Detected by Resting-State fMRI

V.M. Stoecklein, S. Wunderlich, B. Papazov, N. Thon, M. Schmutzer, R. Schinner, H. Zimmermann, T. Liebig, J. Ricke, H. Liu, J.-C. Tonn, C. Schichor and S. Stoecklein
American Journal of Neuroradiology July 2023, 44 (7) 814-819; DOI: https://doi.org/10.3174/ajnr.A7915
V.M. Stoecklein
aFrom the Department of Neurosurgery (V.M.S., N.T., M.S., J.-C.T., C.S.)
bGerman Cancer Consortium (V.M.S., N.T., J.-C.T., C.S.)
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
  • ORCID record for V.M. Stoecklein
S. Wunderlich
cDepartment of Radiology (S.W., B.P., R.S., J.R., S.S.)
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
B. Papazov
cDepartment of Radiology (S.W., B.P., R.S., J.R., S.S.)
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
N. Thon
aFrom the Department of Neurosurgery (V.M.S., N.T., M.S., J.-C.T., C.S.)
bGerman Cancer Consortium (V.M.S., N.T., J.-C.T., C.S.)
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
  • ORCID record for N. Thon
M. Schmutzer
aFrom the Department of Neurosurgery (V.M.S., N.T., M.S., J.-C.T., C.S.)
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
  • ORCID record for M. Schmutzer
R. Schinner
cDepartment of Radiology (S.W., B.P., R.S., J.R., S.S.)
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
H. Zimmermann
dDepartment of Neuroradiology (H.Z., T.L.), Ludwig-Maximilians-University Munich, Munich, Germany
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
  • ORCID record for H. Zimmermann
T. Liebig
dDepartment of Neuroradiology (H.Z., T.L.), Ludwig-Maximilians-University Munich, Munich, Germany
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
  • ORCID record for T. Liebig
J. Ricke
cDepartment of Radiology (S.W., B.P., R.S., J.R., S.S.)
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
H. Liu
eDepartment of Radiology (H.L.), Athinoula A. Martinos Center for Biomedical Imaging, Massachusetts General Hospital/Haard Medical School, Boston, Massachusetts
fDepartment of Neuroscience (H.L.), Medical University of South Carolina, Charleston, South Carolina
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
  • ORCID record for H. Liu
J.-C. Tonn
aFrom the Department of Neurosurgery (V.M.S., N.T., M.S., J.-C.T., C.S.)
bGerman Cancer Consortium (V.M.S., N.T., J.-C.T., C.S.)
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
  • ORCID record for J.-C. Tonn
C. Schichor
aFrom the Department of Neurosurgery (V.M.S., N.T., M.S., J.-C.T., C.S.)
bGerman Cancer Consortium (V.M.S., N.T., J.-C.T., C.S.)
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
  • ORCID record for C. Schichor
S. Stoecklein
cDepartment of Radiology (S.W., B.P., R.S., J.R., S.S.)
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
  • ORCID record for S. Stoecklein
  • Article
  • Figures & Data
  • Info & Metrics
  • Responses
  • References
  • PDF
Loading

Article Figures & Data

Figures

  • Tables
  • FIG 1.
    • Download figure
    • Open in new tab
    • Download powerpoint
    FIG 1.

    Comparison of the DCI in patients without and with PTBE. The left column shows the mean (SD) in patients without PTBE (n = 15) compared with the mean (SD) in patients with PTBE (right column, n = 14) (*P = .04, Mann-Whitney test).

  • FIG 2.
    • Download figure
    • Open in new tab
    • Download powerpoint
    FIG 2.

    Individual connectome maps in patients with meningiomas. A, Connectome map of a patient with a large meningioma (contrast-enhanced T1WI, first image from the left) with extensive PTBE (T2WI, second image from the left). Connectome analysis shows extensive impairment of functional connectivity in widespread brain regions in both hemispheres (third and fourth images from the left). B, Connectome map of a patient with a small meningioma (contrast-enhanced T1WI, first image from the left), which still causes extensive PTBE (T1WI, second image from the left). Connectome analysis shows extensively impaired connectivity in the whole brain with a focus on regions with PTBE (third and fourth images from the left). C, Connectome map of a patient with a large meningioma (contrast-enhanced T1WI, first image from the left) without PTBE (T2WI, second image from left). Connectome analysis shows minimal disturbance of functional connectivity adjacent to the tumor (third and fourth images from the left).

Tables

  • Figures
  • Patient characteristics

    ParameterNo PTBEPTBESignificance
    Age (mean ± SEM) (yr)53 ± 2.666 ± 2.9P = .0014
    Sex2 Male, 13 female5 Male, 9 femaleP = .21
    Tumor volume (mean ± SEM) (cm3)15.0 ± 3.735.5± 8.2P = .0124
    Tumor location
     Frontal66P = .97
     Temporal54
     Parietal30
     Occipital11
     Multiple lobes03
    • Note:—SEM indicates standard error of the mean.

PreviousNext
Back to top

In this issue

American Journal of Neuroradiology: 44 (7)
American Journal of Neuroradiology
Vol. 44, Issue 7
1 Jul 2023
  • Table of Contents
  • Index by author
  • Complete Issue (PDF)
Advertisement
Print
Download PDF
Email Article

Thank you for your interest in spreading the word on American Journal of Neuroradiology.

NOTE: We only request your email address so that the person you are recommending the page to knows that you wanted them to see it, and that it is not junk mail. We do not capture any email address.

Enter multiple addresses on separate lines or separate them with commas.
Perifocal Edema in Patients with Meningioma is Associated with Impaired Whole-Brain Connectivity as Detected by Resting-State fMRI
(Your Name) has sent you a message from American Journal of Neuroradiology
(Your Name) thought you would like to see the American Journal of Neuroradiology web site.
CAPTCHA
This question is for testing whether or not you are a human visitor and to prevent automated spam submissions.
Cite this article
V.M. Stoecklein, S. Wunderlich, B. Papazov, N. Thon, M. Schmutzer, R. Schinner, H. Zimmermann, T. Liebig, J. Ricke, H. Liu, J.-C. Tonn, C. Schichor, S. Stoecklein
Perifocal Edema in Patients with Meningioma is Associated with Impaired Whole-Brain Connectivity as Detected by Resting-State fMRI
American Journal of Neuroradiology Jul 2023, 44 (7) 814-819; DOI: 10.3174/ajnr.A7915

Citation Manager Formats

  • BibTeX
  • Bookends
  • EasyBib
  • EndNote (tagged)
  • EndNote 8 (xml)
  • Medlars
  • Mendeley
  • Papers
  • RefWorks Tagged
  • Ref Manager
  • RIS
  • Zotero
0 Responses
Respond to this article
Share
Bookmark this article
Perifocal Edema in Meningiomas&Brain Connectivity
V.M. Stoecklein, S. Wunderlich, B. Papazov, N. Thon, M. Schmutzer, R. Schinner, H. Zimmermann, T. Liebig, J. Ricke, H. Liu, J.-C. Tonn, C. Schichor, S. Stoecklein
American Journal of Neuroradiology Jul 2023, 44 (7) 814-819; DOI: 10.3174/ajnr.A7915
del.icio.us logo Twitter logo Facebook logo Mendeley logo
  • Tweet Widget
  • Facebook Like
  • Google Plus One
Purchase

Jump to section

  • Article
    • Abstract
    • ABBREVIATIONS:
    • MATERIALS AND METHODS
    • RESULTS
    • DISCUSSION
    • CONCLUSIONS
    • Footnotes
    • References
  • Figures & Data
  • Info & Metrics
  • Responses
  • References
  • PDF

Related Articles

  • No related articles found.
  • PubMed
  • Google Scholar

Cited By...

  • Denoising Strategies of Functional Connectivity MRI Data in Lesional and Non-Lesional Brain Diseases
  • Quantification of Brain Functional Connectivity Deviations in Individuals: A Scoping Review of Functional MRI Studies
  • Reducing Functional Dysconnectivity in Schizophrenia Spectrum Disorders
  • Crossref (3)
  • Google Scholar

This article has been cited by the following articles in journals that are participating in Crossref Cited-by Linking.

  • Functional connectivity MRI provides an imaging correlate for chimeric antigen receptor T-cell-associated neurotoxicity
    Sophia Stoecklein, Stephan Wunderlich, Boris Papazov, Michael Winkelmann, Wolfgang G Kunz, Katharina Mueller, Katharina Ernst, Veit M Stoecklein, Viktoria Blumenberg, Philipp Karschnia, Veit L Bücklein, Kai Rejeski, Christian Schmidt, Michael von Bergwelt-Baildon, Joerg-Christian Tonn, Jens Ricke, Hesheng Liu, Jan Remi, Marion Subklewe, Louisa von Baumgarten, Florian Schoeberl
    Neuro-Oncology Advances 2023 5 1
  • The unseen impact – a deep dive into neurocognitive impairment among patients with intracranial meningiomas: a comprehensive systematic review of the literature
    Mohammed A. Fouda, Samantha Kallman, Rebecca Boorstin, Amanda Sacks-Zimmerman, Susan C. Pannullo, H. Allison Bender
    Neurosurgical Review 2024 47 1
  • Correlation of Molecular Status with Preoperative Olfactory Function in Olfactory Groove Meningioma
    Dino Podlesek, Friederike Beyer, Majd Alkhatib, Dirk Daubner, Mido Max Hijazi, Jerry Hadi Juratli, Susanne Weise, Ilker Y. Eyüpoglu, Gabriele Schackert, Tareq A. Juratli, Thomas Hummel
    Cancers 2024 16 8

More in this TOC Section

  • Kurtosis and Epileptogenic Tubers: A Pilot Study
  • Glutaric Aciduria Type 1: DK vs. Conventional MRI
  • WM Neuroaxonal Loss in Type 1 Diabetes
Show more FUNCTIONAL

Similar Articles

Advertisement

Indexed Content

  • Current Issue
  • Accepted Manuscripts
  • Article Preview
  • Past Issues
  • Editorials
  • Editor's Choice
  • Fellows' Journal Club
  • Letters to the Editor
  • Video Articles

Cases

  • Case Collection
  • Archive - Case of the Week
  • Archive - Case of the Month
  • Archive - Classic Case

More from AJNR

  • Trainee Corner
  • Imaging Protocols
  • MRI Safety Corner
  • Book Reviews

Multimedia

  • AJNR Podcasts
  • AJNR Scantastics

Resources

  • Turnaround Time
  • Submit a Manuscript
  • Submit a Video Article
  • Submit an eLetter to the Editor/Response
  • Manuscript Submission Guidelines
  • Statistical Tips
  • Fast Publishing of Accepted Manuscripts
  • Graphical Abstract Preparation
  • Imaging Protocol Submission
  • Evidence-Based Medicine Level Guide
  • Publishing Checklists
  • Author Policies
  • Become a Reviewer/Academy of Reviewers
  • News and Updates

About Us

  • About AJNR
  • Editorial Board
  • Editorial Board Alumni
  • Alerts
  • Permissions
  • Not an AJNR Subscriber? Join Now
  • Advertise with Us
  • Librarian Resources
  • Feedback
  • Terms and Conditions
  • AJNR Editorial Board Alumni

American Society of Neuroradiology

  • Not an ASNR Member? Join Now

© 2025 by the American Society of Neuroradiology All rights, including for text and data mining, AI training, and similar technologies, are reserved.
Print ISSN: 0195-6108 Online ISSN: 1936-959X

Powered by HighWire