Article Figures & Data
Figures
- FIG 1.
A case of head and neck cancer recurrence. A 72-year-old man after an operation and radiation therapy for squamous cell carcinoma of the floor of the mouth. The left side of the floor of the mouth shows some high signal intensity (arrows) on T2WI (A) and mild enhancement (dotted arrows) on postcontrast fat-suppressed T1WI (B). The ADC map (C) shows low signal (arrowheads), with an nADCmean of 1.38. DCE-MR imaging (D, Vp; E, Ve; F, Ktrans) shows increased parameters (thick arrows), with an nVp of 7.33, nVe of 3.93, and nKtrans of 5.44.
- FIG 2.
Benign posttreatment change of head and neck cancer in a 64-year-old woman after surgery and radiation therapy for mucoepidermoid carcinoma of the left parotid gland. The left parotid surgical bed shows low signal intensity (arrow) on T2WI (A) and mild enhancement (dotted arrow) on postcontrast fat-suppressed T1WI (B). The ADC map (C) shows no prominent low signal (arrowhead), with an nADCmean of 1.75. DCE-MR imaging (D, Vp; E, Ve; F, Ktrans) shows no increased parameters (thick arrows) with an nVp of 0.33, nVe of 0.33, and nKtrans of 0.03.
- FIG 3.
Receiver operating characteristic curves. AUROCCs for nVp (solid line) and nKtrans (dashed line) are 0.74 and 0.79, respectively (A). AUROCCs for nAUC (solid line) and nWI (dashed line) are 0.80 and 0.79, respectively (B). AUROCCs for the combination of normalized DCE-MR imaging parameters (nVp, nKtrans, nAUC, and nWI) (dashed line) and the combination of normalized DCE-MR imaging parameters and nADCmean (solid line) are 0.81 and 0.97, respectively (C).
Tables
DCE-MR imaging and ADC parameters
Recurrence (n = 25)
(Median [Range])Benign Posttreatment Change
(n = 26) (Median [Range])P Value DCE parameters Vp 0.09 (0.02–0.22) 0.05 (0.01–0.14) Reference Vp 0.01 (0.01–0.04) 0.02 (0.01–0.05) nVp 7.00 (0.50–17.33) 2.02 (0.33–14.33) .003a Ve 0.39 (0.07–0.98) 0.28 (0.01–1.08) Reference Ve 0.14 (0.01–0.26) 0.19 (0.07–0.67) nVe 2.55 (0.32–97.66) 1.56 (0.01–6.35) .014 Ktrans 0.25 (0.06–1.02) 0.13 (0.01–0.39) Reference Ktrans 0.08 (0.01–0.15) 0.11 (0.04–0.33) nKtrans 3.87 (0.66–101.00) 1.27 (0.03–8.00) <.001a Kep 0.61 (0.39–2.03) 0.50 (0.16–2.12) Reference Kep 0.48 (0.02–1.36) 0.55 (0.32–1.06) nKep 1.45 (0.47–26.17) 0.96 (0.28–2.69) .009 AUC 28,265 (3523–427,571) 11,887 (537–335,025) Reference AUC 7119 (615–188,345) 7890 (3530–185,938) nAUC 3.34 (1.31–20.81) 1.39 (0.01–9.96) <.001a WI 1.03 (0.29–2102.33) 0.70 (0.06–38.00) Reference WI 0.38 (0.02–696.00) 0.33 (0.07–21.24) nWI 4.13 (0.99–20.17) 1.70 (0.07–32.48) <.001a WO 0.68 (0.01–472.33) 0.57 (0.01–18.99) Reference WO 0.08 (0.01–117.00) 0.43 (0.02–27.28) nWO 3.78 (0.31–292.88) 1.35 (0–109.00) .016 ADC value 1.01 (0.55–1.30) 1.61 (1.02–2.53) Reference ADC 0.79 (0.56–0.94) 0.78 (0.67–0.99) nADCmean 1.31 (0.77–1.65) 2.07 (1.39–3.04) <.001a ↵a Statistically significant.
