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Research ArticleHead &; Neck

ADC for Differentiation between Posttreatment Changes and Recurrence in Head and Neck Cancer: A Systematic Review and Meta-analysis

A. Baba, R. Kurokawa, M. Kurokawa, O. Hassan, Y. Ota and A. Srinivasan
American Journal of Neuroradiology March 2022, 43 (3) 442-447; DOI: https://doi.org/10.3174/ajnr.A7431
A. Baba
aFrom the Division of Neuroradiology, Department of Radiology, University of Michigan, Ann Arbor, Michigan
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R. Kurokawa
aFrom the Division of Neuroradiology, Department of Radiology, University of Michigan, Ann Arbor, Michigan
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  • ORCID record for R. Kurokawa
M. Kurokawa
aFrom the Division of Neuroradiology, Department of Radiology, University of Michigan, Ann Arbor, Michigan
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O. Hassan
aFrom the Division of Neuroradiology, Department of Radiology, University of Michigan, Ann Arbor, Michigan
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Y. Ota
aFrom the Division of Neuroradiology, Department of Radiology, University of Michigan, Ann Arbor, Michigan
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A. Srinivasan
aFrom the Division of Neuroradiology, Department of Radiology, University of Michigan, Ann Arbor, Michigan
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  • FIG 1.
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    FIG 1.

    The PRISMA 2020 flow chart for the article-selection process. After applying the selection criteria, we identified 6 articles for the systematic review and meta-analysis.

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    FIG 2.

    Forest plot (association of ADC values between recurrence and posttreatment change). The ADC value of recurrence was significantly smaller than that of posttreatment changes in head and neck cancer.

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    FIG 3.

    Funnel plot (association of ADC value between recurrence and posttreatment change). The funnel plot identified 2 studies over the pseudo 95% CI.

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    FIG 4.

    Receiver operating characteristic curve of the cutoff of ADC values between recurrence and posttreatment change.

Tables

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  • Characteristics of 6 studies

    AuthorsYearRegionPeriodTotal No.NOS
    Tshering Vogel et al52013Switzerland2007–2010464
    Razek et al72015EgyptNR414
    Vaid et al112017India8 months804
    Becker et al102018SwitzerlandNR744
    Jajodia et al132019India1 year624
    Huang et al142019China2016–2017625
    • Note:—NR indicates not reported; NOS, Newcastle-Ottawa scale.

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American Journal of Neuroradiology: 43 (3)
American Journal of Neuroradiology
Vol. 43, Issue 3
1 Mar 2022
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A. Baba, R. Kurokawa, M. Kurokawa, O. Hassan, Y. Ota, A. Srinivasan
ADC for Differentiation between Posttreatment Changes and Recurrence in Head and Neck Cancer: A Systematic Review and Meta-analysis
American Journal of Neuroradiology Mar 2022, 43 (3) 442-447; DOI: 10.3174/ajnr.A7431

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ADC for Differentiation between Posttreatment Changes and Recurrence in Head and Neck Cancer: A Systematic Review and Meta-analysis
A. Baba, R. Kurokawa, M. Kurokawa, O. Hassan, Y. Ota, A. Srinivasan
American Journal of Neuroradiology Mar 2022, 43 (3) 442-447; DOI: 10.3174/ajnr.A7431
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