Atlas-Based Quantification of DTI Measures in a Typically Developing Pediatric Spinal Cord

Spinal cord WM atlas. A, An atlas of spinal white matter tracts. B, Generated white matter atlas of the pediatric spinal cord overlaid on a b₀ image. The selected tracts are labeled with multiple colors: 1) right lateral corticospinal tract, 2) left lateral corticospinal tract, 3) right fasciculus cuneatus, 4) left fasciculus cuneatus, 5) right fasciculus gracilis, 6) left fasciculus gracilis, yellow: gray matter, light blue; unlabeled white matter. C, The C3 level is marked green on the sagittal T2-weighted scan.

Violin plots of normative FA (A), MD (B), AD (C), and RD (D) indices averaged across 30 healthy pediatric subjects for 34 ROIs. ROIs are subdivided in to 30 WM tracts; 3 combined labels of DF, LF, and VF; and 1 label for the entire WM. IVST indicates lateral vestibulospinal tract; vRST, ventral reticulospinal tract; FC, fasciculus cuneatus; ICST, lateral corticospinal tract; TST, tectospinal tract; SL, spinal lemniscus (spinothalamic and spinoreticular tracts); FG, fasciculus gracilis; SOT, spino-olivary tract; mLF, medial longitudinal tract; vCST, ventral corticospinal tract; vIRST, ventrolateral reticulospinal tract; IRST, lateral reticulospinal tract; RST, rubrospinal tract; vSCT, ventral spinocerebellar tract; mRST, medial reticulospinal tract; WM, white matter; DF, dorsal column; LF, lateral funiculi; VF, ventral funiculi; L, left; R, right.