The Safety of Intra-arterial Tirofiban during Endovascular Therapy after Intravenous Thrombolysis

References

1. 1.↵
   1. Berkhemer OA,
   2. Fransen PS,
   3. Beumer D, et al

   . A randomized trial of intraarterial treatment for acute ischemic stroke. N Engl J Med 2015;372:11–20 doi:10.1056/NEJMoa1411587 pmid:25517348

   CrossRefPubMedWeb of Science
2. 2.↵
   1. Campbell BC,
   2. Mitchell PJ,
   3. Kleinig TJ, et al

   . Endovascular therapy for ischemic stroke with perfusion-imaging selection. N Engl J Med 2015;372:1009–18 doi:10.1056/NEJMoa1414792 pmid:25671797

   CrossRefPubMed
3. 3.↵
   1. Goyal M,
   2. Demchuk AM,
   3. Menon BK, et al

   . Randomized assessment of rapid endovascular treatment of ischemic stroke. N Engl J Med 2015;372:1019–30 doi:10.1056/NEJMoa1414905 pmid:25671798

   CrossRefPubMed
4. 4.↵
   1. Saver JL,
   2. Goyal M,
   3. Bonafe A, et al

   . Stent-retriever thrombectomy after intravenous t-PA vs. t-PA alone in stroke. N Engl J Med 2015;372:2285–95 doi:10.1056/NEJMoa1415061 pmid:25882376

   CrossRefPubMed
5. 5.↵
   1. Jovin TG,
   2. Chamorro A,
   3. Cobo E, et al

   . Thrombectomy within 8 hours after symptom onset in ischemic stroke. N Engl J Med 2015;372:2296–2306 doi:10.1056/NEJMoa1503780 pmid:25882510

   CrossRefPubMed
6. 6.↵
   1. Powers WJ,
   2. Rabinstein AA,
   3. Ackerson T, et al

   . Guidelines for the early management of patients with acute ischemic stroke: 2019 update to the 2018 guidelines for the early management of acute ischemic stroke: a guideline for healthcare professionals from the American Heart Association/American Stroke Association. Stroke 2019;50:e344–418 doi:10.1161/STR.0000000000000211 pmid:31662037

   CrossRefPubMed
7. 7.↵
   1. Emberson J,
   2. Lees KR,
   3. Lyden P, et al

   . Effect of treatment delay, age, and stroke severity on the effects of intravenous thrombolysis with alteplase for acute ischaemic stroke: a meta-analysis of individual patient data from randomised trials. Lancet 2014;384:1929–35 doi:10.1016/S0140-6736(14)60584-5 pmid:25106063

   CrossRefPubMedWeb of Science
8. 8.↵
   1. Goyal M,
   2. Menon BK,
   3. van Zwam WH, et al

   . Endovascular thrombectomy after large-vessel ischaemic stroke: a meta-analysis of individual patient data from five randomised trials. Lancet 2016;387:1723–31 doi:10.1016/S0140-6736(16)00163-X pmid:26898852

   CrossRefPubMed
9. 9.↵
   1. Teng D,
   2. Pannell JS,
   3. Rennert RC, et al

   . Endothelial trauma from mechanical thrombectomy in acute stroke: In vitro live-cell platform with animal validation. Stroke 2015;46:1099–1106 doi:10.1161/STROKEAHA.114.007494 pmid:25712942

   Abstract/FREE Full Text
10. 10.↵
    1. Yang M,
    2. Huo X,
    3. Miao Z, et al

    . Platelet glycoprotein IIb/IIIa receptor inhibitor tirofiban in acute ischemic stroke. Drugs 2019;79:515–29 doi:10.1007/s40265-019-01078-0 pmid:30838514

    CrossRefPubMed
11. 11.↵
    1. Luo Y,
    2. Yang Y,
    3. Xie Y, et al

    . Therapeutic effect of pre-operative tirofiban on patients with acute ischemic stroke with mechanical thrombectomy within 6-24 hours. Interv Neuroradiol 2019;25:705–09 doi:10.1177/1591019919851167 pmid:31112428

    CrossRefPubMed
12. 12.↵
    1. Kellert L,
    2. Hametner C,
    3. Rohde S, et al

    . Endovascular stroke therapy: tirofiban is associated with risk of fatal intracerebral hemorrhage and poor outcome. Stroke 2013;44:1453–55 doi:10.1161/STROKEAHA.111.000502 pmid:23463755

    Abstract/FREE Full Text
13. 13.↵
    1. Zhao W,
    2. Che R,
    3. Shang S, et al

    . Low-dose tirofiban improves functional outcome in acute ischemic stroke patients treated with endovascular thrombectomy. Stroke 2017;48:3289–94 doi:10.1161/STROKEAHA.117.019193 pmid:29127270

    Abstract/FREE Full Text
14. 14.↵
    1. Pan X,
    2. Zheng D,
    3. Zheng Y, et al

    . Safety and efficacy of tirofiban combined with endovascular treatment in acute ischaemic stroke. Eur J Neurol 2019;26:1105–10 doi:10.1111/ene.13946 pmid:30793464

    CrossRefPubMed
15. 15.↵
    1. Lee JI,
    2. Gliem M,
    3. Gerdes G, et al

    . Safety of bridging antiplatelet therapy with the GPIIb-IIIa inhibitor tirofiban after emergency stenting in stroke. PLoS One 2017;12:e0190218 doi:10.1371/journal.pone.0190218 pmid:29281734

    CrossRefPubMed
16. 16.↵
    1. Zhang S,
    2. Hao Y,
    3. Tian X, et al

    . Safety of intra-arterial tirofiban administration in ischemic stroke patients after unsuccessful mechanical thrombectomy. J Vasc Interv Radiol 2019;30:141 doi:10.1016/j.jvir.2018.08.021 pmid:30611627

    CrossRefPubMed
17. 17.↵
    1. Kang DH,
    2. Yoon W,
    3. Kim SK, et al

    . Endovascular treatment for emergent large vessel occlusion due to severe intracranial atherosclerotic stenosis. J Neurosurg 2018 June 1:1–8 [Epub ahead of print] doi:10.3171/2018.1.JNS172350 pmid:29932374

    CrossRefPubMed
18. 18.↵
    1. Kang DH,
    2. Kim YW,
    3. Hwang YH, et al

    . Instant reocclusion following mechanical thrombectomy of in situ thromboocclusion and the role of low-dose intra-arterial tirofiban. Cerebrovasc Dis 2014;37:350–55 doi:10.1159/000362435 pmid:24941966

    CrossRefPubMed
19. 19.↵
    1. Lee JS,
    2. Lee SJ,
    3. Yoo JS, et al

    . Prognosis of acute intracranial atherosclerosis-related occlusion after endovascular treatment. J Stroke 2018;20:394–403 doi:10.5853/jos.2018.01627 pmid:30309234

    CrossRefPubMed
20. 20.↵
    1. Fiorelli M,
    2. Bastianello S,
    3. von Kummer R, et al

    . Hemorrhagic transformation within 36 hours of a cerebral infarct: relationships with early clinical deterioration and 3-month outcome in the European Cooperative Acute Stroke Study I (Ecass I) cohort. Stroke 1999;30:2280–84 doi:10.1161/01.str.30.11.2280 pmid:10548658

    Abstract/FREE Full Text
21. 21.↵
    1. Evans MR,
    2. White P,
    3. Cowley P, et al

    . Revolution in acute ischaemic stroke care: a practical guide to mechanical thrombectomy. Pract Neurol 2017;17:252–65 doi:10.1136/practneurol-2017-001685 pmid:28647705

    Abstract/FREE Full Text
22. 22.↵
    1. Heck DV,
    2. Brown MD

    . Carotid stenting and intracranial thrombectomy for treatment of acute stroke due to tandem occlusions with aggressive antiplatelet therapy may be associated with a high incidence of intracranial hemorrhage. J Neurointerv Surg 2015;7:170–75 doi:10.1136/neurintsurg-2014-011224 pmid:25387730

    Abstract/FREE Full Text
23. 23.↵
    1. Ernst M,
    2. Butscheid F,
    3. Fiehler J, et al

    . Glycoprotein IIb/IIIa inhibitor bridging and subsequent endovascular therapy in vertebrobasilar occlusion in 120 patients. Clin Neuroradiol 2016;26:169–75 doi:10.1007/s00062-014-0341-3 pmid:25164695

    CrossRefPubMed
24. 24.↵
    1. Kim KS,
    2. Fraser JF,
    3. Grupke S, et al

    . Management of antiplatelet therapy in patients undergoing neuroendovascular procedures. J Neurosurg 2018;129:890–905 doi:10.3171/2017.5.JNS162307 pmid:29192856

    CrossRefPubMed
25. 25.↵
    1. Harder S,
    2. Klinkhardt U,
    3. Alvarez JM

    . Avoidance of bleeding during surgery in patients receiving anticoagulant and/or antiplatelet therapy: pharmacokinetic and pharmacodynamic considerations. Clin Pharmacokinet 2004;43:963–81 doi:10.2165/00003088-200443140-00002 pmid:15530128

    CrossRefPubMedWeb of Science
26. 26.↵
    1. McClellan KJ,
    2. Goa KL

    . Tirofiban: a review of its use in acute coronary syndromes. Drugs 1998;56:1067–80 doi:10.2165/00003495-199856060-00017 pmid:9878994

    CrossRefPubMedWeb of Science
27. 27.↵
    1. Kwon JH,
    2. Shin SH,
    3. Weon YC, et al

    . Intra-arterial adjuvant tirofiban after unsuccessful intra-arterial thrombolysis of acute ischemic stroke: preliminary experience in 16 patients. Neuroradiology 2011;53:779–85 doi:10.1007/s00234-011-0939-y pmid:21808986

    CrossRefPubMed
28. 28.↵
    1. Goh DH,
    2. Jin SC,
    3. Jeong HW, et al

    . Mechanical Solitaire thrombectomy with low-dose booster tirofiban injection. Neurointervention 2016;11:114–19 doi:10.5469/neuroint.2016.11.2.114 pmid:27621948

    CrossRefPubMed
29. 29.↵
    1. Kim YW,
    2. Sohn SI,
    3. Yoo J, et al

    . Local tirofiban infusion for remnant stenosis in large vessel occlusion: tirofiban assist study. BMC Neurol 2020;20:284 doi:10.1186/s12883-020-01864-4 pmid:32689957

    CrossRefPubMed
30. 30.↵
    1. Baek JH,
    2. Kim BM,
    3. Kim DJ, et al

    . Importance of truncal-type occlusion in stentriever-based thrombectomy for acute stroke. Neurology 2016;87:1542–50 doi:10.1212/WNL.0000000000003202 pmid:27629085

    CrossRefPubMed
31. 31.
    1. Chang Y,
    2. Kim BM,
    3. Bang OY, et al

    . Rescue stenting for failed mechanical thrombectomy in acute ischemic stroke: a multicenter experience. Stroke 2018;49:958–64 doi:10.1161/STROKEAHA.117.020072 pmid:29581342

    Abstract/FREE Full Text
32. 32.↵
    1. Lee JS,
    2. Hong JM,
    3. Lee KS, et al

    . Primary stent retrieval for acute intracranial large artery occlusion due to atherosclerotic disease. J Stroke 2016;18:96–101 doi:10.5853/jos.2015.01347 pmid:26467196

    CrossRefPubMed
33. 33.↵
    1. Yoon W,
    2. Kim SK,
    3. Park MS, et al

    . Endovascular treatment and the outcomes of atherosclerotic intracranial stenosis in patients with hyperacute stroke. Neurosurgery 2015;76:680–86; Discussion 686 doi:10.1227/NEU.0000000000000694 pmid:25988927

    CrossRefPubMed
34. 34.↵
    1. Liebeskind DS,
    2. Cotsonis GA,
    3. Saver JL, et al

    . for the Warfarin-Aspirin Symptomatic Intracranial Disease (WASID) Investigators. Collaterals dramatically alter stroke risk in intracranial atherosclerosis. Ann Neurol 2011;69:963–74 doi:10.1002/ana.22354 pmid:21437932

    CrossRefPubMed
35. 35.↵
    1. Li W,
    2. Lin L,
    3. Zhang M, et al

    . Safety and preliminary efficacy of early tirofiban treatment after alteplase in acute ischemic stroke patients. Stroke 2016;47:2649–51 doi:10.1161/STROKEAHA.116.014413 pmid:27608821

    Abstract/FREE Full Text
36. 36.↵
    1. Yang J,
    2. Wu Y,
    3. Gao X, et al

    . Intraarterial versus intravenous tirofiban as an adjunct to endovascular thrombectomy for acute ischemic stroke. Stroke 2020;51:2925–33 doi:10.1161/STROKEAHA.120.029994

    CrossRefPubMed