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AJNR Awards, New Junior Editors, and more. Read the latest AJNR updates

Research ArticleExtracranial Vascular

Carotid Intraplaque Hemorrhage and Stenosis: At What Stage of Plaque Progression Does Intraplaque Hemorrhage Occur, and When is It Most Likely to Be Associated with Symptoms?

A.S. Larson, W. Brinjikji, L. Savastano, A.A. Rabinstein, L. Saba, J. Huston and J.C. Benson
American Journal of Neuroradiology July 2021, 42 (7) 1285-1290; DOI: https://doi.org/10.3174/ajnr.A7133
A.S. Larson
aFrom the Departments of Radiology (A.S.L., W.B., J.H., J.C.B.)
bNeurosurgery (A.S.L., W.B., L. Savastano)
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W. Brinjikji
aFrom the Departments of Radiology (A.S.L., W.B., J.H., J.C.B.)
bNeurosurgery (A.S.L., W.B., L. Savastano)
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L. Savastano
bNeurosurgery (A.S.L., W.B., L. Savastano)
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A.A. Rabinstein
cNeurology (A.A.R.), Mayo Clinic, Rochester, Minnesota
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L. Saba
dDepartment of Radiology (L. Saba), University of Cagliari, Cagliari, Italy
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J. Huston
aFrom the Departments of Radiology (A.S.L., W.B., J.H., J.C.B.)
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J.C. Benson
aFrom the Departments of Radiology (A.S.L., W.B., J.H., J.C.B.)
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Article Information

vol. 42 no. 7 1285-1290
DOI 
https://doi.org/10.3174/ajnr.A7133
PubMed 
33888452

Published By 
American Journal of Neuroradiology
Print ISSN 
0195-6108
Online ISSN 
1936-959X
History 
  • Received June 23, 2020
  • Accepted after revision February 8, 2021
  • Published online July 13, 2021.

Article Versions

  • Latest version (April 22, 2021 - 08:48).
  • You are viewing the most recent version of this article.
Copyright & Usage 
© 2021 by American Journal of Neuroradiology

Author Information

  1. A.S. Larsona,b,
  2. W. Brinjikjia,b,
  3. L. Savastanob,
  4. A.A. Rabinsteinc,
  5. L. Sabad,
  6. J. Hustona and
  7. J.C. Bensona
  1. aFrom the Departments of Radiology (A.S.L., W.B., J.H., J.C.B.)
  2. bNeurosurgery (A.S.L., W.B., L. Savastano)
  3. cNeurology (A.A.R.), Mayo Clinic, Rochester, Minnesota
  4. dDepartment of Radiology (L. Saba), University of Cagliari, Cagliari, Italy
  1. Please address correspondence to Anthony Larson, BS, Mayo Clinic Department of Radiology, 200 First St SW, Rochester, MN 55905; e-mail: lars4689{at}umn.edu; @TonyLarsonBS; @WBrinjikji; @SavastanoPh
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A.S. Larson, W. Brinjikji, L. Savastano, A.A. Rabinstein, L. Saba, J. Huston, J.C. Benson
Carotid Intraplaque Hemorrhage and Stenosis: At What Stage of Plaque Progression Does Intraplaque Hemorrhage Occur, and When is It Most Likely to Be Associated with Symptoms?
American Journal of Neuroradiology Jul 2021, 42 (7) 1285-1290; DOI: 10.3174/ajnr.A7133

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Carotid Intraplaque Hemorrhage and Stenosis: At What Stage of Plaque Progression Does Intraplaque Hemorrhage Occur, and When is It Most Likely to Be Associated with Symptoms?
A.S. Larson, W. Brinjikji, L. Savastano, A.A. Rabinstein, L. Saba, J. Huston, J.C. Benson
American Journal of Neuroradiology Jul 2021, 42 (7) 1285-1290; DOI: 10.3174/ajnr.A7133
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Cited By...

  • High Wall Shear Stress Is Related to Complicated American Heart Association Lesion Type VI Plaques in Mild-to-Moderate ICA Stenosis: A 3D Cardiovascular MRI Study
  • MR Imaging of Carotid Artery Atherosclerosis: Updated Evidence on High-Risk Plaque Features and Emerging Trends
  • Nonstenotic Carotid Plaques and Embolic Stroke of Undetermined Source: A Multimodality Review
  • Another Step toward the Understanding of * Carotid Artery Pathology
  • Crossref (17)
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This article has been cited by the following articles in journals that are participating in Crossref Cited-by Linking.

  • MR Imaging of Carotid Artery Atherosclerosis: Updated Evidence on High-Risk Plaque Features and Emerging Trends
    J.C. Benson, L. Saba, G. Bathla, W. Brinjikji, V. Nardi, G. Lanzino
    American Journal of Neuroradiology 2023 44 8
  • Temporal Trends and Determinants of Stroke Risk in Patients With Medically Treated Asymptomatic Carotid Stenosis
    Michiel H.F. Poorthuis, Yoel Solomon, Reinier A.R. Herings, Frank L.J. Visseren, L. Jaap Kappelle, Michiel L. Bots, Ina Rissanen, Gert J. de Borst
    Stroke 2023 54 7
  • The application of the nnU-Net-based automatic segmentation model in assisting carotid artery stenosis and carotid atherosclerotic plaque evaluation
    Ying Zhu, Liwei Chen, Wenjie Lu, Yongjun Gong, Ximing Wang
    Frontiers in Physiology 2022 13
  • Integrated head and neck imaging of symptomatic patients with stroke using simultaneous non-contrast cardiovascular magnetic resonance angiography and intraplaque hemorrhage imaging as compared with digital subtraction angiography
    Yuxi Jia, Xiaoming Liu, Lan Zhang, Xiangchuang Kong, Shuo Chen, Lei Zhang, Jiazheng Wang, Shenglei Shu, Jia Liu, Xiaona Fu, Dingxi Liu, Jing Wang, Heshui Shi
    Journal of Cardiovascular Magnetic Resonance 2022 24 1
  • Nonstenotic Carotid Plaques and Embolic Stroke of Undetermined Source: A Multimodality Review
    A.S. Larson, W. Brinjikji, A. Lekah, J.P. Klaas, G. Lanzino, J. Huston, L. Saba, J.C. Benson
    American Journal of Neuroradiology 2023 44 2
  • A clinical-radiomics combined model based on carotid atherosclerotic plaque for prediction of ischemic stroke
    Na Han, Wanjun Hu, Yurong Ma, Yu Zheng, Songhong Yue, Laiyang Ma, Jie Li, Jing Zhang
    Frontiers in Neurology 2024 15
  • In vitro analysis of carotid lesions using a preliminary microwave sensor to detect vulnerable plaques: Correlation with histology, Duplex ultrasound examination, and computed tomography scanner: The Imaging and Microwave Phenotyping Assessment of Carotid stenosis Threat (IMPACT) study
    Rania Shahbaz, Etienne Charpentier, Maharajah Ponnaiah, Frédérique Deshours, Hamid Kokabi, Isabelle Brochériou, Gilles Le Naour, Alban Redheuil, Fabien Koskas, Jean-Michel Davaine
    JVS-Vascular Science 2024 5
  • Unfinished debate: Why IPH-based metrics are still needed—An Editorial for “Signal intensity and volume of carotid intraplaque hemorrhage on magnetic resonance imaging and the risk of ipsilateral cerebrovascular events: the Plaque At RISK (PARISK) study”
    Chun Yuan, Gador Canton, Thomas S. Hatsukami
    Journal of Cardiovascular Magnetic Resonance 2024 26 2
  • Another Step toward the Understanding of Carotid Artery Pathology
    A. Podlasek, R.J. Simpson
    American Journal of Neuroradiology 2021 42 7
  • Benefits of prophylactic carotid revascularization in patients with asymptomatic carotid artery stenosis undergoing coronary artery bypass surgery: A narrative review
    Mateja Kaja Jezovnik, Pavel Poredos, Peter Poredos
    Vascular Medicine 2025 30 1

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  • Proximal Vertebral Artery Variants and Embryology
  • High-Risk Plaque Features in Carotid MRI
  • Nonstenotic Carotid Plaques and Stroke Review
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