Article Figures & Data
Figures
- FIG 1.
The anatomic locations for the 3 brain cortical regions that showed significant differences (FDR-corrected P ≤ .05) in mean cortical thickness between neonates born to normal-weight-versus-obese women: the left pars opercularis (LPO) gyrus (A), the left pars triangularis (LPT) gyrus (B), and the left rostral middle frontal (LFMF) gyrus (C). The comparison of mean cortical thickness for these 3 regions in these groups of neonates is illustrated in D.
- FIG 2.
Partial correlation analysis showed significant negative correlations (P < .05) between maternal body fat mass percentage measured at ∼12 weeks of pregnancy and neonate brain mean cortical thickness measured at ∼2 weeks’ postnatal age in the left pars opercularis (LPO) gyrus, left pars triangularis (LPT) gyrus, and left rostral middle frontal (LRMF) gyrus.
Tables
Demographic information of the study participants
Normal Weight (n = 28) Obese (n = 16) P Value Maternal BMI (kg/m2) 22.2 (SD, 1.9) 33.2 (SD, 1.5) <.001 Maternal fat mass (%) 28.8 (SD, 4.2) 44.0 (SD, 3.9) <.001 Maternal age at pregnancy (yr) 28.7 (SD, 2.9) 30.7 (SD, 5.0) .19 Maternal IQ 107 (SD, 9.2) 106.6 (SD, 8.3) .50 Gestational age (day) 275.1 (SD, 6.7) 274.7 (SD, 6.4) .96 Neonate sex (boy/girl) 15/13 8/8 .83 Birth weight (kg) 3.5 (SD, 0.5) 3.6 (SD, 0.5) .38 Birth length (cm) 50.6 (SD, 2.8) 50.5 (SD, 2.5) .89 Head circumference (cm) 36.2 (SD, 1.1) 36.0 (SD, 0.8) .25 Neonate age at MR imaging (day) 14.3 (SD, 1.6) 14.3 (SD, 1.7) 1 Postmenstrual age at MR imaging (day) 289.4 (SD, 6.4) 289 (SD, 6.3) .93 Neonate race White/African American/American Indian/other) 22/2/1/3 10/5/1/0 .18 Mother’s education No college/some college/graduate degree 3/17/8 0/9/7 .30 Father’s education NA/no college/some college/graduate degree) 1/24/3/0 2/10/4/0 .20 Mother’s income (US dollar) NA/ ≤ 20k/20–50k/>50k) 6/6/12/4 1/3/9/3 .57 Father’s income (US dollar) NA/≤ 20k/20–50k/>50k) 1/0/14/13 3/0/6/7 .23 Note:—NA indicates not applicable.
