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Research ArticlePediatrics
Open Access

Association of Isolated Congenital Heart Disease with Fetal Brain Maturation

C. Jaimes, V. Rofeberg, C. Stopp, C.M. Ortinau, A. Gholipour, K.G. Friedman, W. Tworetzky, J. Estroff, J.W. Newburger, D. Wypij, S.K. Warfield, E. Yang and C.K. Rollins
American Journal of Neuroradiology August 2020, 41 (8) 1525-1531; DOI: https://doi.org/10.3174/ajnr.A6635
C. Jaimes
aFrom the Departments of Radiology (C.J., A.G., J.E., S.K.W., E.Y.), Cardiology (V.R., C.S., K.G.F., W.T., J.W.N., D.W.), Neurology (C.K.R.), Fetal-Neonatal Neuroimaging and Developmental Science Center (C.J.), Boston Children’s Hospital, Boston, Massachusetts
bRadiology (C.J., A.G., J.E., S.K.W., E.Y.), Pediatrics (K.G.F., W.T., J.W.N., D.W.), Neurology (C.K.R.), Harvard Medical School, Boston, Massachusetts
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V. Rofeberg
aFrom the Departments of Radiology (C.J., A.G., J.E., S.K.W., E.Y.), Cardiology (V.R., C.S., K.G.F., W.T., J.W.N., D.W.), Neurology (C.K.R.), Fetal-Neonatal Neuroimaging and Developmental Science Center (C.J.), Boston Children’s Hospital, Boston, Massachusetts
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C. Stopp
aFrom the Departments of Radiology (C.J., A.G., J.E., S.K.W., E.Y.), Cardiology (V.R., C.S., K.G.F., W.T., J.W.N., D.W.), Neurology (C.K.R.), Fetal-Neonatal Neuroimaging and Developmental Science Center (C.J.), Boston Children’s Hospital, Boston, Massachusetts
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C.M. Ortinau
cPediatrics (C.M.O.), Washington University in St. Louis, St. Louis, Missouri
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A. Gholipour
aFrom the Departments of Radiology (C.J., A.G., J.E., S.K.W., E.Y.), Cardiology (V.R., C.S., K.G.F., W.T., J.W.N., D.W.), Neurology (C.K.R.), Fetal-Neonatal Neuroimaging and Developmental Science Center (C.J.), Boston Children’s Hospital, Boston, Massachusetts
bRadiology (C.J., A.G., J.E., S.K.W., E.Y.), Pediatrics (K.G.F., W.T., J.W.N., D.W.), Neurology (C.K.R.), Harvard Medical School, Boston, Massachusetts
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K.G. Friedman
aFrom the Departments of Radiology (C.J., A.G., J.E., S.K.W., E.Y.), Cardiology (V.R., C.S., K.G.F., W.T., J.W.N., D.W.), Neurology (C.K.R.), Fetal-Neonatal Neuroimaging and Developmental Science Center (C.J.), Boston Children’s Hospital, Boston, Massachusetts
bRadiology (C.J., A.G., J.E., S.K.W., E.Y.), Pediatrics (K.G.F., W.T., J.W.N., D.W.), Neurology (C.K.R.), Harvard Medical School, Boston, Massachusetts
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W. Tworetzky
aFrom the Departments of Radiology (C.J., A.G., J.E., S.K.W., E.Y.), Cardiology (V.R., C.S., K.G.F., W.T., J.W.N., D.W.), Neurology (C.K.R.), Fetal-Neonatal Neuroimaging and Developmental Science Center (C.J.), Boston Children’s Hospital, Boston, Massachusetts
bRadiology (C.J., A.G., J.E., S.K.W., E.Y.), Pediatrics (K.G.F., W.T., J.W.N., D.W.), Neurology (C.K.R.), Harvard Medical School, Boston, Massachusetts
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J. Estroff
aFrom the Departments of Radiology (C.J., A.G., J.E., S.K.W., E.Y.), Cardiology (V.R., C.S., K.G.F., W.T., J.W.N., D.W.), Neurology (C.K.R.), Fetal-Neonatal Neuroimaging and Developmental Science Center (C.J.), Boston Children’s Hospital, Boston, Massachusetts
bRadiology (C.J., A.G., J.E., S.K.W., E.Y.), Pediatrics (K.G.F., W.T., J.W.N., D.W.), Neurology (C.K.R.), Harvard Medical School, Boston, Massachusetts
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J.W. Newburger
aFrom the Departments of Radiology (C.J., A.G., J.E., S.K.W., E.Y.), Cardiology (V.R., C.S., K.G.F., W.T., J.W.N., D.W.), Neurology (C.K.R.), Fetal-Neonatal Neuroimaging and Developmental Science Center (C.J.), Boston Children’s Hospital, Boston, Massachusetts
bRadiology (C.J., A.G., J.E., S.K.W., E.Y.), Pediatrics (K.G.F., W.T., J.W.N., D.W.), Neurology (C.K.R.), Harvard Medical School, Boston, Massachusetts
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D. Wypij
aFrom the Departments of Radiology (C.J., A.G., J.E., S.K.W., E.Y.), Cardiology (V.R., C.S., K.G.F., W.T., J.W.N., D.W.), Neurology (C.K.R.), Fetal-Neonatal Neuroimaging and Developmental Science Center (C.J.), Boston Children’s Hospital, Boston, Massachusetts
bRadiology (C.J., A.G., J.E., S.K.W., E.Y.), Pediatrics (K.G.F., W.T., J.W.N., D.W.), Neurology (C.K.R.), Harvard Medical School, Boston, Massachusetts
dBiostatistics (D.W.), Harvard T.H. Chan School of Public Health, Boston, Massachusetts.
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S.K. Warfield
aFrom the Departments of Radiology (C.J., A.G., J.E., S.K.W., E.Y.), Cardiology (V.R., C.S., K.G.F., W.T., J.W.N., D.W.), Neurology (C.K.R.), Fetal-Neonatal Neuroimaging and Developmental Science Center (C.J.), Boston Children’s Hospital, Boston, Massachusetts
bRadiology (C.J., A.G., J.E., S.K.W., E.Y.), Pediatrics (K.G.F., W.T., J.W.N., D.W.), Neurology (C.K.R.), Harvard Medical School, Boston, Massachusetts
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E. Yang
aFrom the Departments of Radiology (C.J., A.G., J.E., S.K.W., E.Y.), Cardiology (V.R., C.S., K.G.F., W.T., J.W.N., D.W.), Neurology (C.K.R.), Fetal-Neonatal Neuroimaging and Developmental Science Center (C.J.), Boston Children’s Hospital, Boston, Massachusetts
bRadiology (C.J., A.G., J.E., S.K.W., E.Y.), Pediatrics (K.G.F., W.T., J.W.N., D.W.), Neurology (C.K.R.), Harvard Medical School, Boston, Massachusetts
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C.K. Rollins
aFrom the Departments of Radiology (C.J., A.G., J.E., S.K.W., E.Y.), Cardiology (V.R., C.S., K.G.F., W.T., J.W.N., D.W.), Neurology (C.K.R.), Fetal-Neonatal Neuroimaging and Developmental Science Center (C.J.), Boston Children’s Hospital, Boston, Massachusetts
bRadiology (C.J., A.G., J.E., S.K.W., E.Y.), Pediatrics (K.G.F., W.T., J.W.N., D.W.), Neurology (C.K.R.), Harvard Medical School, Boston, Massachusetts
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Article Information

vol. 41 no. 8 1525-1531
DOI 
https://doi.org/10.3174/ajnr.A6635
PubMed 
32646947

Published By 
American Journal of Neuroradiology
Print ISSN 
0195-6108
Online ISSN 
1936-959X
History 
  • Received December 3, 2019
  • Accepted after revision April 30, 2020
  • Published online August 12, 2020.

Article Versions

  • Latest version (July 9, 2020 - 07:06).
  • You are viewing the most recent version of this article.
Copyright & Usage 
© 2020 by American Journal of Neuroradiology Indicates open access to non-subscribers at www.ajnr.org

Author Information

  1. C. Jaimesa,b,
  2. V. Rofeberga,
  3. C. Stoppa,
  4. C.M. Ortinauc,
  5. A. Gholipoura,b,
  6. K.G. Friedmana,b,
  7. W. Tworetzkya,b,
  8. J. Estroffa,b,
  9. J.W. Newburgera,b,
  10. D. Wypija,b,d,
  11. S.K. Warfielda,b,
  12. E. Yanga,b and
  13. C.K. Rollinsa,b
  1. aFrom the Departments of Radiology (C.J., A.G., J.E., S.K.W., E.Y.), Cardiology (V.R., C.S., K.G.F., W.T., J.W.N., D.W.), Neurology (C.K.R.), Fetal-Neonatal Neuroimaging and Developmental Science Center (C.J.), Boston Children’s Hospital, Boston, Massachusetts
  2. bRadiology (C.J., A.G., J.E., S.K.W., E.Y.), Pediatrics (K.G.F., W.T., J.W.N., D.W.), Neurology (C.K.R.), Harvard Medical School, Boston, Massachusetts
  3. cPediatrics (C.M.O.), Washington University in St. Louis, St. Louis, Missouri
  4. dBiostatistics (D.W.), Harvard T.H. Chan School of Public Health, Boston, Massachusetts.
  1. Please address correspondence to Caitlin K. Rollins, MD, Department of Neurology, Cardiac Neurodevelopmental Program, Boston Children’s Hospital, 300 Longwood Ave, Boston, MA; e-mail: caitlin.rollins{at}childrens.harvard.edu; @camilojaimesc
View Full Text

Funding

  • National Institute of Neurological Disorders and Stroke

    K23NS101120
  • American Academy of Neurology

    Clinical Research Training Fellowship
  • Society for Pediatric Radiology

    Young Investigator Award
  • Boston Children’s Hospital

    Office of Faculty Development, Career Development
  • National Heart, Lung, and Blood Institute

    Pediatric Heart Network Scholar Award
  • National Institute of Biomedical Imaging and Bioengineering

    R01EB013248; R01EB018988
  • Mend a Heart Foundation

  • Brain and Behavior Research Foundation

    Distinguished Investigator; NARSAD Young Investigator
  • Schlaeger Fellowship for Neuroscience Research

    Young Investigator Award
  • McKnight Foundation Technological Innovations in Neuroscience Award

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Cite this article
C. Jaimes, V. Rofeberg, C. Stopp, C.M. Ortinau, A. Gholipour, K.G. Friedman, W. Tworetzky, J. Estroff, J.W. Newburger, D. Wypij, S.K. Warfield, E. Yang, C.K. Rollins
Association of Isolated Congenital Heart Disease with Fetal Brain Maturation
American Journal of Neuroradiology Aug 2020, 41 (8) 1525-1531; DOI: 10.3174/ajnr.A6635

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Association of Isolated Congenital Heart Disease with Fetal Brain Maturation
C. Jaimes, V. Rofeberg, C. Stopp, C.M. Ortinau, A. Gholipour, K.G. Friedman, W. Tworetzky, J. Estroff, J.W. Newburger, D. Wypij, S.K. Warfield, E. Yang, C.K. Rollins
American Journal of Neuroradiology Aug 2020, 41 (8) 1525-1531; DOI: 10.3174/ajnr.A6635
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    Human Brain Mapping 2021 42 17
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